High-throughput determination of linezolid in human plasma by liquid chromatography-tandem mass spectrometry

Journal of Liquid Chromatography and Related Technologies

Volumn 34, Issue 8, 2011, Pages 591-600

  Vlase, Laurian ^a   Muntean, Dana ^a   Cuciureanu, Magdalena ^b   Cuciureanu, Rodica ^b   Gocan, Simion ^c  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^c BABE BOLYAI UNIVERSITY   (Romania)

Author keywords

Human plasma; Linezolid; Liquid chromatography; Mass spectrometry

Indexed keywords

AMMONIUM FORMATE; BIOAVAILABILITY STUDY; CLINICAL PHARMACOKINETICS; CONCENTRATION RANGES; ELECTROSPRAY ION SOURCES; FREEZE-THAW; HIGH-THROUGHPUT; HUMAN PLASMAS; ION TRANSITION; ISOCRATIC ELUTION; LC/MS/MS; LEAST SQUARES REGRESSION; LINEZOLID; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MASS SPECTROMETRIC DETECTION; MOBILE PHASE; MULTIPLE-REACTION MONITORING MODES; RETENTION TIME; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RUNTIMES; SAMPLE PREPARATION; THERAPEUTIC DRUG MONITORING;

ACETONITRILE; AMMONIUM COMPOUNDS; BIOCHEMISTRY; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION SOURCES; IONS; LIQUIDS; MASS SPECTROMETRY; PATIENT MONITORING; PLASMA (HUMAN); PLASMAS;

CHROMATOGRAPHY;

ACETONITRILE; AMMONIUM FORMATE; LINEZOLID;

ARTICLE; CALIBRATION; DIAGNOSTIC ACCURACY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; DRUG STABILITY; DRUG STRUCTURE; ELECTROSPRAY; ELUTION; HIGH THROUGHPUT SCREENING; HUMAN; IONIZATION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; RELIABILITY; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

EID: 79955991109     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2010.535480     Document Type: Article

References (18)

1. Perry, C. M.; Jarvis, B. Linezolid: A Review of Its Use in the Management of Serious Gram-Positive Infections. Drugs 2001, 61(4), 525-551. (Pubitemid 32368068)
2. Diekema, D. I.; Jones, R. N. Oxazolidinones: A Review. Drugs 2000, 59(1), 7-16. (Pubitemid 30150569)
3. Swaney, S. M.; Aoki, H.; Ganoza, M. C.; Sinaberger, D. L. The Oxazolidinone Linezolid Inhibits Initiation of Protein Synthesis in Bacteria. Antimicrob. Agents Chemother. 1998, 42, 3251-3255. (Pubitemid 28553749)
4. Borner, K.; Borner, E.; Lode H. Determination of Linezolid in Human Serum and Urine by High-Performance Liquid Chromatography. Internat. J. Antimicrob. Agents 2001, 18, 253-258. (Pubitemid 32979198)
5. Boak, L.; Li, J.; Nation, R.; Rayner, C. High-Performance Liquid Chromatographic Method for Simple and Rapid Determination of Linezolid in Human Plasma. Biomed. Chromatogr. 2006, 20, 782-786. (Pubitemid 44203174)
6. Kitahashi, T.; Furuta, I. Method Development for Determining the Antibacterial Linezolid in Human Serum by Micellar Electrokinetic Capillary Chromatography. J. Pharm. Biomed. Anal. 2002, 30, 1411-1416. (Pubitemid 35284351)
7. Toutain, J.; Boselli, E.; Djabarouti, S.; Allaouchiche, B.; Xuereb, F.; Bernadou, J. M.; Ba, B.; Saux, M. C.; Breilh, D. Determination of Linezolid in Plasma and Bronchoalveolar Lavage High-Performance Liquid Chromatography with Ultraviolet Detection Using a Fully Automated Extraction Method. J. Chromatogr. B 2004, 813, 145-150. (Pubitemid 39535440)
8. Buerger, C.; Joukhadar, C.; Muller, M.; Kloft, C. Development of a Liquid Chromatography Method for the Determination of Linezolid and Its Application to In Vitro and Human Microdialysis Samples. J. Chromatogr. B 2003, 796, 155-164. (Pubitemid 38352719)
9. Phillips, O. A.; Abdel-Hamid, M. E.; Al-Hassawi, N. A. Determination of Linezolid in Human Plasma by LC-MS-MS. Analyst 2001, 126, 609-614. (Pubitemid 32453036)
10. Li, J.; Rayner, C.; Dixon, R.; Nation, S. Simple Method for the Assay of Linezolid in Brain Heart Infusion Broth by High-Performance Liquid Chromatography. Biomed Chromatogr. 2004, 18, 1-5. (Pubitemid 38208256)
11. Tobin, C. M.; Sunderland, J.; Lovering, A. M.; MacGowan, A. P. A High Performance Liquid Chromatography (HPLC) Assay for Linezolid in Continuous Ambulatory Peritoneal Dialysis Fluid (CAPDF). J. Antimicrob. Chemotherapy 2003, 51, 1041-1042. (Pubitemid 36503445)
12. Peng, G. W.; Stryd, R.; Murata, S.; Igrashi, M.; Chiba, K.; Aoyama, H.; Aoyama, M.; Zenki, T.; Ozawa, N. Determination of Linezolid in Plasma by Reversed-Phase High-Performance Liquid Chromatography. J. Pharm. Biomed. Anal. 1999, 20, 65-73. (Pubitemid 29206584)
13. Ba, B. B.; Nso, B. B.; Quentin, C.; Saux, M. C. Determination of Linezolid in Growth Media by High-Performance Liquid Chromatography with On-Line Extraction. J. Chromatogr. B 2007, 854, 104-108. (Pubitemid 46962374)
14. Annesley, T. M. Ion Suppression in Mass Spectrometry. Clin. Chem. 2003, 49(7), 1041-1044. (Pubitemid 36751088)
15. Birmingham, M. C.; Rayner, C. R.; Meagher, A. K.; Flavin, S. M., Batts, D. H.; Schentag, J. J. Linezolid for the Treatment of Multidrug-Resistant, Gram-Positive Infections: Experience from a Compassionate-Use Program. Clin. Infect. Dis. 2003, 36, 159-168. (Pubitemid 36143412)
16. The European Agency for the Evaluation of Medicinal Products. Note for Guidance on the Investigation of Bioavailability and Bioequivalence, European Medicines Agency: London, UK, 2001; (CPMP/WP/QWP/401/8).
17. U. S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research. Guidance for Industry. Bioavailability and Bioequivalence Studies for Orally Administrated Drug Products - General Considerations, Rockville, USA, 2003; http://www.fda.gov/ cder/guidance/index.htm.
18. U. S. Department of Health and Human Services, Food and Drug Administration. Guidance for Industry - Bioanalytical Method Validation, Rockville, USA, 2001.