CD70 is selectively expressed on Th1 but not on Th2 cells and is required for Th1-type immune responses

Journal of Investigative Dermatology

Volumn 131, Issue 6, 2011, Pages 1252-1261

  Kawamura, Tatsuyoshi ^a   Ogawa, Youichi ^a   Shimozato, Osamu ^b,c   Ando, Takashi ^a   Nakao, Atsuhito ^a   Kobata, Tetsuji ^b,d   Okumura, Ko ^b   Yagita, Hideo ^b   Shimada, Shinji ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c CHIBA CANCER CENTER   (Japan)

^d DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CD27 ANTIGEN; CD70 ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; INTERLEUKIN 4; INTERLEUKIN 5; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD70; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; ASTHMA; CD4+ T LYMPHOCYTE; CELL EXPANSION; CELL INFILTRATION; CELL ISOLATION; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTACT ALLERGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DENDRITIC CELL; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATORY CELL; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; TH1 CELL; TH2 CELL;

EID: 79955990545     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.36     Document Type: Article

References (43)

1. Abbas AK, Murphy KM, Sher A (1996) Functional diversity of helper T lymphocytes. Nature 383:787-93 (Pubitemid 26372655)
2. Agematsu K, Kobata T, Sugita K et al. (1995) Direct cellular communications between CD45R0 and CD45RA T cell subsets via CD27/CD70. J Immunol 154:3627-35
3. Arens R, Tesselaar K, Baars PA et al. (2001) Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion. Immunity 15:801-12 (Pubitemid 34008507)
4. Beishuizen CR, Kragten NA, Boon L et al. (2009) Chronic CD70-driven costimulation impairs IgG responses by instructing T cells to inhibit germinal center B cell formation through FasL-Fas interactions. J Immunol 183:6442-51
5. Borst J, Hendriks J, Xiao Y (2005) CD27 and CD70 in T cell and B cell activation. Curr Opin Immunol 17:275-81 (Pubitemid 40692662)
6. Bullock TN, Yagita H (2005) Induction of CD70 on dendritic cells through CD40 or TLR stimulation contributes to the development of CD8+ T cell responses in the absence of CD4+ T cells. J Immunol 174:710-7 (Pubitemid 40094264)
7. D'Ambrosio D, Iellem A, Bonecchi R et al. (1998) Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 Th cells. J Immunol 161:5111-5 (Pubitemid 28519063)
8. French RR, Taraban VY, Crowther GR et al. (2007) Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation. Blood 109:4810-5 (Pubitemid 46827776)
9. Hashimoto-Okada M, Kitawaki T, Kadowaki N et al. (2009) The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4(+) T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans. Int Immunol 21:891-904
10. Hendriks J, Gravestein LA, Tesselaar K et al. (2000) CD27 is required for generation and long-term maintenance of T cell immunity. Nat Immunol 1:433-40
11. Hendriks J, Xiao Y, Borst J (2003) CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool. J Exp Med 198:1369-80 (Pubitemid 37392482)
12. Ho IC, Glimcher LH (2002) Transcription: tantalizing times for T cells. Cell 109(Suppl):S109-20 (Pubitemid 34457856)
13. Hoshino A, Tanaka Y, Akiba H et al. (2003) Critical role for OX40 ligand in the development of pathogenic Th2 cells in a murine model of asthma. Eur J Immunol 33:861-9 (Pubitemid 36546673)
14. Ingulli E, Mondino A, Khoruts A et al. (1997) In vivo detection of dendritic cell antigen presentation to CD4(+) T cells. J Exp Med 185:2133-41 (Pubitemid 27265997)
15. Iwamoto S, Ishida M, Takahashi K et al. (2005) Lipopolysaccharide stimulation converts vigorously washed dendritic cells (DCs) to nonexhausted DCs expressing CD70 and evoking long-lasting type 1 T cell responses. J Leukoc Biol 78:383-92 (Pubitemid 41061310)
16. Kawamura T, Azuma M, Kayagaki N et al. (1999) Fas/Fas ligand-mediated elimination of antigen-bearing Langerhans cells in draining lymph nodes. Br J Dermatol 141:201-5 (Pubitemid 29397984)
17. Kearney ER, Pape KA, Loh DY et al. (1994) Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1:327-39
18. Lohning M, Stroehmann A, Coyle AJ et al. (1998) T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Natl Acad Sci USA 95:6930-5 (Pubitemid 28278084)
19. Manocha M, Rietdijk S, Laouar A et al. (2009) Blocking CD27-CD70 costimu-latory pathway suppresses experimental colitis. J Immunol 183:270-6
20. Matter M, Odermatt B, Yagita H et al. (2006) Elimination of chronic viral infection by blocking CD27 signaling. J Exp Med 203:2145-55 (Pubitemid 44352235)
21. McAdam AJ, Chang TT, Lumelsky AE et al. (2000) Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells. J Immunol 165:5035-40
22. Meyers JH, Ryu A, Monney L et al. (2002) Cutting edge: CD94/NKG2 is expressed on Th1 but not Th2 cells and costimulates Th1 effector functions. J Immunol 169:5382-6 (Pubitemid 35291631)
23. Monney L, Sabatos CA, Gaglia JL et al. (2002) Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 415:536-41 (Pubitemid 34130609)
24. Nolte MA, Van Olffen RW, Van Gisbergen KP et al. (2009) Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology. Immunol Rev 229:216-31
25. Nuriya S, Enomoto S, Azuma M (2001) The role of CTLA-4 in murine contact hypersensitivity. J Invest Dermatol 116:764-8 (Pubitemid 32467657)
26. Oshima H, Nakano H, Nohara C et al. (1998) Characterization of murine CD70 by molecular cloning and mAb. Int Immunol 10:517-26 (Pubitemid 28182109)
27. Peperzak V, Xiao Y, Veraar EA et al. (2010) CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production. J Clin Invest 120:168-78
28. Rowley TF, Al-Shamkhani A (2004) Stimulation by soluble CD70 promotes strong primary and secondary CD8+ cytotoxic T cell responses in vivo. J Immunol 172:6039-46 (Pubitemid 38621205)
29. Sallusto F, Lenig D, Mackay CR et al. (1998) Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 187:875-83 (Pubitemid 28141661)
30. Sanchez PJ, McWilliams JA, Haluszczak C et al. (2007) Combined TLR/CD40 stimulation mediates potent cellular immunity by regulating dendritic cell expression of CD70 in vivo. J Immunol 178:1564-72 (Pubitemid 46154627)
31. Soares H, Waechter H, Glaichenhaus N et al. (2007) A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo. J Exp Med 204:1095-106 (Pubitemid 46798153)
32. Sumi T, Ishida W, Ojima A et al. (2008) CD27 and CD70 do not play a critical role in the development of experimental allergic conjunctivitis in mice. Immunol Lett 119:91-6
33. Szabo SJ, Dighe AS, Gubler U et al. (1997) Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med 185:817-24 (Pubitemid 27119865)
34. Taraban VY, Rowley TF, Al-Shamkhani A (2004) Cutting edge: a critical role for CD70 in CD8 T cell priming by CD40-licensed APCs. J Immunol 173:6542-6 (Pubitemid 39541037)
35. Tesselaar K, Xiao Y, Arens R et al. (2003) Expression of the murine CD27 ligand CD70 in vitro and in vivo. J Immunol 170:33-40 (Pubitemid 36026120)
36. Van Gisbergen KP, Van Olffen RW, Van Beek J et al. (2009) Protective CD8 T cell memory is impaired during chronic CD70-driven costimulation. J Immunol 182:5352-62
37. Van Oosterwijk MF, Juwana H, Arens R et al. (2007) CD27-CD70 interactions sensitise naive CD4+ T cells for IL-12-induced Th1 cell development. Int Immunol 19:713-8 (Pubitemid 47078715)
38. Wang B, Fujisawa H, Zhuang L et al. (2000) CD4+ Th1 and CD8+ type 1 cytotoxic T cells both play a crucial role in the full development of contact hypersensitivity. J Immunol 165:6783-90 (Pubitemid 32001144)
39. Watanabe N, Arase H, Kurasawa K et al. (1997) Th1 and Th2 subsets equally undergo Fas-dependent and -independent activation-induced cell death. Eur J Immunol 27:1858-64 (Pubitemid 27345998)
40. Watts TH (2005) TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 23:23-68 (Pubitemid 40563164)
41. Wills-Karp M (1999) Immunologic basis of antigen-induced airway hyperre-sponsiveness. Annu Rev Immunol 17:255-81 (Pubitemid 29241125)
42. Xiao Y, Peperzak V, Keller AM et al. (2008) CD27 instructs CD4+ T cells to provide help for the memory CD8+ T cell response after protein immunization. J Immunol 181:1071-82
43. Xu D, Chan WL, Leung BP et al. (1998) Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. J Exp Med 188:1485-92 (Pubitemid 28489585)