Modeling of the structure and interactions of the B. anthracis antitoxin, MoxX: Deletion mutant studies highlight its modular structure and repressor function

Journal of Computer-Aided Molecular Design

Volumn 25, Issue 3, 2011, Pages 275-291

  Chopra, Nikita ^a   Agarwal, Shivangi ^b,c   Verma, Shashikala ^b   Bhatnagar, Sonika ^a   Bhatnagar, Rakesh ^b  

^a NETAJI SUBHAS INSTITUTE OF TECHNOLOGY   (India)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Antitoxin DNA complex; Deletion mutants; Docking; Molecular dynamics; Molecular modeling; MoxXT; Peptide design; Repressor; RHH motif; Toxin antitoxin complex

Indexed keywords

BACTERIA; BACTERIOLOGY; BINDING ENERGY; BIOINFORMATICS; DIMERS; DNA; MOLECULAR MODELING; PEPTIDES; STRUCTURAL DESIGN; TOXIC MATERIALS;

ANTITOXIN-DNA COMPLEX; AUTOREGULATIONS; DELETION MUTANTS; DNA COMPLEX; DOCKING; MOXXT; PEPTIDE DESIGN; REPRESSOR; RIBBON-HELIX-HELIX MOTIF; TOXIN-ANTITOXIN COMPLEX;

MOLECULAR DYNAMICS;

ANTITOXIN; BACTERIAL TOXIN; HELIX LOOP HELIX PROTEIN; LABILE ANTITOXIN; PEMK LIKE TOXIN; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS ANTHRACIS; BACILLUS SUBTILIS; CONTROLLED STUDY; DELETION MUTANT; DNA FRAGMENTATION; GENE INSERTION; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REPRESSOR GENE; STRUCTURAL HOMOLOGY; TOXIN ANALYSIS; TOXIN STRUCTURE; TRANSCRIPTION REGULATION;

EID: 79955989586     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-011-9419-z     Document Type: Article

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