First-trimester markers of aneuploidy in women positive for HIV

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 118, Issue 7, 2011, Pages 844-848

  Savvidou, M D ^a   Samuel, I ^b   Syngelaki, A ^c   Poulton, M ^b   Nicolaides, K H ^c  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b Department of Sexual Health and HIV ^*  (United Kingdom)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Chromosomal abnormalities; first trimester; free human chorionic gonadotrophin; HIV; pregnancy; pregnancy associated plasma protein A

Indexed keywords

BIOLOGICAL MARKER; CHORIONIC GONADOTROPIN BETA SUBUNIT; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; PREGNANCY ASSOCIATED PLASMA PROTEIN A; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ADULT; ANEUPLOIDY; ANTIVIRAL THERAPY; ARTICLE; CHROMOSOME ABERRATION; CONTROLLED STUDY; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; NUCHAL TRANSLUCENCY MEASUREMENT; PRENATAL SCREENING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK FACTOR;

ADULT; ANEUPLOIDY; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; FEMALE; HIV SEROPOSITIVITY; HOSPITALS, TEACHING; HUMANS; NUCHAL TRANSLUCENCY MEASUREMENT; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREGNANCY TRIMESTER, FIRST; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; REPRODUCTIVE CONTROL AGENTS; SENSITIVITY AND SPECIFICITY; TRISOMY; ULTRASONOGRAPHY, PRENATAL;

EID: 79955974858     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/j.1471-0528.2010.02767.x     Document Type: Article

References (19)

1. UNAIDS. 2008 Report on the global AIDS epidemic. Status of the global HIV epidemic. [].
2. Health Protection Agency. HIV in the United Kingdom. 2009 Report. [].
3. Townsend CL, Cortina-Borja M, Peckham CS, de Ruiter A, Lyall H, Tookey PA,. Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006. AIDS 2008; 22: 973-81. (Pubitemid 351652248)
4. Nicolaides KH, Spencer K, Avgidou K, Faiola S, Falcon O,. Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening. Ultrasound Obstet Gynecol 2005; 25: 221-6. (Pubitemid 40432687)
5. National Collaborating Centre for Women's and Children's Health. Antenatal Care: Routine Care for the Healthy Pregnant Woman. London: National Institute for Clinical Excellence, 2008.
6. Kagan KO, Wright D, Spencer K, Molina FS, Nicolaides KH,. First-trimester screening for trisomy 21 by free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A: impact of maternal and pregnancy characteristics. Ultrasound Obstet Gynecol 2008; 31: 493-502.
7. Spencer K, Bindra R, Nicolaides KH,. Maternal weight correction of maternal serum PAPP-A and free beta-hCG MoM when screening for trisomy 21 in the first trimester of pregnancy. Prenat Diagn 2003; 23: 851-5. (Pubitemid 37279873)
8. Yudin MH, Prosen TL, Landers DV,. Multiple-marker screening in human immunodeficiency virus-positive pregnant women: screen positivity rates with the triple and quad screens. Am J Obstet Gynecol 2003; 189: 973-6. (Pubitemid 37373880)
9. Einstein FH, Wright RL, Trentacoste S, Gross S, Merkatz IR, Bernstein PS,. The impact of protease inhibitors on maternal serum screening analyte levels in pregnant women who are HIV positive. Am J Obstet Gynecol 2004; 191: 1004-8. (Pubitemid 39298149)
10. Gross S, Castillo W, Crane M, Espinosa B, Carter S, DeVeaux R, et al. Maternal serum alpha-fetoprotein and human chorionic gonadotropin levels in women with human immunodeficiency virus. Am J Obstet Gynecol 2003; 188: 1052-6. (Pubitemid 36530062)
11. Le Meaux JP, Tsatsaris V, Schmitz T, Fulla Y, Launay O, Goffinet F, et al. Maternal biochemical serum screening for Down syndrome in pregnancy with human immunodeficiency virus infection. Obstet Gynecol 2008; 112: 223-30.
12. Brossard P, Boulvain M, Coll O, Barlow P, Aebi-Popp K, Bischof P, et al. Swiss HIV Cohort Study. Swiss HIV Mother and Child Cohort Study; Is screening for fetal anomalies reliable in HIV-infected pregnant women? A multicentre study. AIDS 2008; 22: 2013-7.
13. Wright D, Kagan KO, Molina FS, Gazzoni A, Nicolaides KH,. A mixture model of nuchal translucency thickness in screening for chromosomal defects. Ultrasound Obstet Gynecol 2008; 31: 376-83.
14. Cruz J, Cruz G, Minekawa R, Maiz N, Nicolaides KH,. Effect of temperature on the measurement of free β-hCG and PAPP-A concentration. Ultrasound Obstet Gynecol 2010; 36: 141-6.
15. Polliotti BM, Gnall-Sazenski S, Laughlin TS, Miller RK,. Inhibitory effects of human chorionic gonadotropin (hCG) preparations on HIV infection of human placenta in vitro. Placenta 2002; 23: S102-6. (Pubitemid 40003788)
16. Lin J, Lojun S, Lei ZM, Wu WX, Peiner SC, Rao CV,. Lymphocytes from pregnant women express human chorionic gonadotropin/luteinizing hormone receptor gene. Mol Cell Endocrinol 1995; 111: R13-7.
17. Kagan KO, Wright D, Valencia C, Maiz N, Nicolaides KH,. Screening for trisomies 21, 18 and 13 by maternal age, fetal nuchal translucency, fetal heart rate, free beta-hCG and pregnancy-associated plasma protein-A. Hum Reprod 2008; 23: 1968-75.
18. Somigliana E, Bucceri AM, Tibaldi C, Alberico S, Ravizza M, Savasi V, et al. Italian Collaborative Study on HIV Infection in Pregnancy; Early invasive diagnostic techniques in pregnant women who are infected with the HIV: a multicenter case series. Am J Obstet Gynecol 2005; 193: 437-42. (Pubitemid 41159539)
19. Mandelbrot L, Jasseron C, Ekoukou D, Batallan A, Bongain A, Pannier E, et al. ANRS French Perinatal Cohort; Amniocentesis and mother-to-child human immunodeficiency virus transmission in the Agence Nationale de Recherches sur le SIDA et les Hépatites Virales French Perinatal Cohort. Am J Obstet Gynecol 2009; 200: 160.