Multispectral imaging of tissue absorption and scattering using spatial frequency domain imaging and a computed-tomography imaging spectrometer

Journal of Biomedical Optics

Volumn 16, Issue 1, 2011, Pages

  Weber, Jessie R ^a   Cuccia, David J ^b   Johnson, William R ^c   Bearman, Gregory H ^d   Durkin, Anthony J ^a   Hsu, Mike ^e   Lin, Alexander ^e   Binder, Devin K ^e   Wilson, Dan ^c   Tromberg, Bruce J ^a,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Modulated Imaging Inc   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^d Snapshot Spectra Inc   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

spectrometry; brain imaging; absorption; scattering; optical properties; intrinsic signal

Indexed keywords

ABSORPTION COEFFICIENTS; BRAIN IMAGING; BRAIN INJURY; CCD CHIP; COMBINED SYSTEM; DATA SETS; IMAGING SPECTROMETERS; LIQUID CRYSTAL TUNABLE FILTER; MOUSE MODELS; MULTI FREQUENCY; MULTISPECTRAL IMAGING; NON-CONTACT; NONCONTACT IMAGING; REDUCED SCATTERING COEFFICIENTS; SCATTERING PROPERTY; SCATTERING SPECTRA; SPATIAL FREQUENCY DOMAINS; SPECTRAL IMAGES; SPECTRAL INFORMATION; STRUCTURED ILLUMINATION; TISSUE ABSORPTION; TISSUE OPTICAL PROPERTIES; WAVELENGTH SCANNING; WIDE-FIELD;

ABSORPTION; FREQUENCY DOMAIN ANALYSIS; LIQUID CRYSTALS; OPTICAL PROPERTIES; SCATTERING; SPECTROMETERS; SPECTROMETRY; TISSUE; TOMOGRAPHY;

ABSORPTION SPECTROSCOPY;

OXYGEN;

ANIMAL; ARTICLE; BRAIN INJURY; BRAIN LEVEL; COMPUTER ASSISTED TOMOGRAPHY; EQUIPMENT; EQUIPMENT DESIGN; IMAGE QUALITY; INSTRUMENTATION; MOUSE; PHOTOMETRY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPECTROSCOPY; SYSTEM ANALYSIS;

ANIMALS; BRAIN CHEMISTRY; BRAIN INJURIES; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; MICE; NEPHELOMETRY AND TURBIDIMETRY; OXYGEN; PHANTOMS, IMAGING; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTRUM ANALYSIS; SYSTEMS INTEGRATION; TOMOGRAPHY, X-RAY COMPUTED;

EID: 79955965470     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3528628     Document Type: Article

References (16)

1. K. Yoo and R. Alfano, Determination of the scattering and absorption lengths from the temporal profile of a backscattered pulse., Opt. Lett. 15 (5), 276-278 (1990). 10.1364/OL.15.000276
2. T. J. Farrell, M. S. Patterson, and B. Wilson, A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the noninvasive determination of tissue optical properties in vivo., Med. Phys. 19 (4), 879-88 (1992). 10.1118/1.596777
3. D. J. Cuccia, Bevilacqua, F., Durkin, A. J., and B. J. Tromberg, Modulated imaging: quantitative analysis and tomography of turbid media in the spatial-frequency domain., Opt. Lett. 30 (11), 1354-6 (2005). 10.1364/OL.30.001354 (Pubitemid 40818563)
4. J. R. Weber, D. J. Cuccia, A. J. Durkin, and B. J. Tromberg, Noncontact imaging of absorption and scattering in layered tissue using spatially modulated structured light., J. Appl. Phys. 105, 102028 (2009). 10.1063/1.3116135
5. D. J. Cuccia, F. Bevilacqua, A. J. Durkin, F. R. Ayers, and B. J. Tromberg, Quantitation and mapping of tissue optical properties using modulated imaging., J. Biomed. Opt. 14, 024012 (2009). 10.1117/1.3088140
6. D. Abookasis, C. C. Lay, M. S. Mathews, M. E. Linskey, R. D. Frostig, and B. J. Tromberg, Imaging cortical absorption, scattering, and hemodynamic response during ischemic stroke using spatially modulated near-infrared illumination., J. Biomed. Opt. 14, 024033 (2009). 10.1117/1.3116709
7. A. Moy, J. G. Kim, E. Y. H. P. Lee, B. J. Tromberg, A. Cerussi, and B. Choi, Brca1p53 Deficient Mouse Breast Tumor Hemodynamics During Hyperoxic Respiratory Challenge Monitored by A Novel Wide-field Functional Imaging (WiFI) System., Proc. SPIE, 7174, 71742L (2009). 10.1117/12.823745
8. M. R. Descour, C. E. Volin, E. L. Dereniak, K. J. Thome, A. B. Schumacher, D. W. Wilson, and P. D. Maker, Demonstration of a high-speed nonscanning imaging spectrometer., Opt. Lett. 22, 271-1273 (1997). 10.1364/OL.22.001271
9. W. R. Johnson, D. W. Wilson, W. Fink, M. Humayun, and G. Bearman, Snapshot hyperspectral imaging in ophthalmology., J. Biomed. Opt. 12 (1), 014036 (2007). 10.1117/1.2434950 (Pubitemid 46681987)
10. C. E. Volin, M. R. Descour, and E. L. Dereniak, Signal-to-noise ratio analysis of the computed-tomography imaging spectrometer., Proc. SPIE 3438, 107 (1998). 10.1117/12.328093 (Pubitemid 35005782)
11. W. R. Johnson, D. W. Wilson, and G. Bearman, Spatial-Spectral Modulating Snapshot Hyperspectral Imager., Appl. Opt. 45, 1898-1908 (2006). 10.1364/AO.45.001898
12. H. van Staveren, C. J. M. Moes, J. van Marie, S. A. Prahl, and M. J. C. van Gemert, Light scattering in Intralipid-10 in the wavelength range of 400-1100 nm., Appl. Opt. 30, 4507-4514 (1991). 10.1364/AO.30.004507
13. A. Ishimaru, Wave Propagation and Scattering in Random Media, IEEE Press, New York (1978).
14. B. J. Tromberg, N. Shah, R. Lanning, A. Cerussi, J. Espinoza, T. Pham, L. Svaasand, and J. Butler, Non-invasive in vivo characterization of breast tumors using photon migration spectroscopy., Neoplasia 2 (1), 26-40 (2000). 10.1038/sj.neo.7900082 (Pubitemid 30123178)
15. J. G. Fox, The Mouse in Biomedical Research, Edition 2, Elsevier, Amsterdam (2007).
16. T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, Diffuse optical measurement of blood flow, blood oxygenation and metabolism in a human brain during sensorimotor cortex activation., Opt. Lett. 29, 1766-1768 (2004). 10.1364/OL.29.001766