Spectral Doppler optical coherence tomography imaging of localized ischemic stroke in a mouse model

Journal of Biomedical Optics

Volumn 15, Issue 6, 2010, Pages

  Yu, Lingfeng ^a,b   Nguyen, Elaine ^a   Liu, Gangjun ^a   Choi, Bernard ^a   Chen, Zhongping ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CARL ZEISS SMT AG   (Germany)

Author keywords

biomedical optics; Doppler; laser Doppler velocimetry; laser speckle imaging; tomography

Indexed keywords

BIOMEDICAL OPTICS; BLOOD CIRCULATION; BLOOD VOLUMES; DOPPLER; DOPPLER OPTICAL COHERENCE TOMOGRAPHY; FLOW DYNAMICS; FLOW INDICES; FLOW INFORMATIONS; HIGH TEMPORAL RESOLUTION; IN-VIVO EXPERIMENTS; ISCHEMIC STROKES; LASER DOPPLER VELOCIMETRY; LASER SPECKLE; LASER SPECKLE IMAGING; MICRO-VASCULATURE; MOUSE MODELS; QUANTITATIVE EVALUATION; RESISTANCE STATE; RESISTIVE INDEX; ROSE BENGAL; SMALL ANIMAL STUDY;

BLOOD; DOPPLER EFFECT; MAPS; PHOTODYNAMIC THERAPY; SPECKLE;

TOMOGRAPHY;

ANIMALIA;

ANIMAL; ARTICLE; BLOOD FLOW VELOCITY; BRAIN ISCHEMIA; C3H MOUSE; DISEASE MODEL; EQUIPMENT; EQUIPMENT DESIGN; HUMAN; INSTRUMENTATION; LASER DOPPLER FLOWMETRY; MOUSE; OPTICAL COHERENCE TOMOGRAPHY; OXIMETRY; PATHOLOGY; PATHOPHYSIOLOGY; SPECTROSCOPY; STROKE;

ANIMALS; BLOOD FLOW VELOCITY; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HUMANS; LASER-DOPPLER FLOWMETRY; MICE; MICE, INBRED C3H; OXIMETRY; SPECTRUM ANALYSIS; STROKE; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 79955958474     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3505016     Document Type: Conference Paper

References (21)

1. B. Ovbiagele, C. S. Kidwell, S. Starkman, and J. L. Saver, Neuroprotective agents for the treatment of acute ischemic stroke., Curr. Neurol. Neurosci. Rep. 3, 9-20 (2003). 10.1007/s11910-003-0031-z (Pubitemid 38898978)
2. Meeting Note: Cerebrovascular Biology and Disease, NHLBI Working Group, National Institutes of Health. (2005).
3. R. D. Frostig, E. E. Lieke, D. Y. Ts'o, and A. Grinvald, Cortical functional architechture and local coupling between neuronal activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signals., Proc. Natl. Acad. Sci. U.S.A. 87, 6082-6086 (1990). 10.1073/pnas.87.16.6082 (Pubitemid 20258960)
4. D. Kleinfeld, P. P. Mitra, F. Helmchen, and W. Denk, Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex., Proc. Nat. Acad. Sci. U.S.A. 95, 15741-15746 (1998). 10.1073/pnas.95.26.15741 (Pubitemid 29018770)
5. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Optical coherence tomography., Science 254, 1178-1181 (1991). 10.1126/science.1957169 (Pubitemid 21917444)
6. Z. Chen, T. E. Milner, D. Dave, and J. S. Nelson, Optical Doppler tomographic imaging of fluid flow velocity in highly scattering media., Opt. Lett. 22, 64-66 (1997). 10.1364/OL.22.000064 (Pubitemid 127593231)
7. Y. Zhao, Z. Chen, C. Saxer, S. Xiang, J. de Boer, and J. Nelson, Phase resolved optical coherence tomography and optical doppler tomography for imaging blood flow in human skin with fast scanning speed and high velocity sensitivity., Opt. Lett. 25, 114-116 (2000). 10.1364/OL.25.000114
8. S. Makita, Y. Hong, M. Yamanari, T. Yatagai, and Y. Yasuno, Optical coherence angiography., Opt. Express 14 (17), 7821-7840 (2006). 10.1364/OE.14.007821 (Pubitemid 44277517)
9. R. K. Wang and L. An, Doppler optical micro-angiography for volumetric imaging of vascular perfusion in vivo., Opt. Express 17, 8926-8940 (2009). 10.1364/OE.17.008926
10. L. Yu and Z. Chen, Doppler variance imaging for three-dimensional retina and choroid angiography., J. Biomed. Opt. 15, 016029 (2010). 10.1117/1.3302806
11. S. M. Narayan, E. M. Santori, and A. W. Toga, Mapping functional activity in rodent cortex using optical intrinsic signals., Cereb. Cortex. 4, 195-204 (1994). 10.1093/cercor/4.2.195 (Pubitemid 24127827)
12. S. M. Narayan, E. M. Santori, A. J. Blood, J. S. Burton, and A. W. Toga, Imaging optical reflectance in rodent barrel and forelimb sensory cortex., Neuroimage 1, 181-90 (1994). 10.1006/nimg.1994.1003 (Pubitemid 24253433)
13. B. Rao, L. Yu, H. K. Chiang, L. C. Zacharias, R. M. Kurtz, B. D. Kuppermann, and Z. Chen, Imaging pulsatile retinal blood flow in human eye., J. Biomed. Opt. 13, 040505 (2008). 10.1117/1.2967986
14. M. Schroeter, S. Jander, and G. Stoll, Non-invasive induction of focal cerebral ischemia in mice by photothrombosis of cortical microvessels: characterization of inflammatory responses., J. Neurosci. Meth. 117, 43-49 (2002). 10.1016/S0165-0270(02)00072-9 (Pubitemid 34663898)
15. J. Lee, M. Park, Y. Kim, K. Moon, S. Joo, T. Kim, J. Kim, and S. Kim, Photochemically induced cerebral ischemia in a mouse model., Surg. Neurol. 67, 620-625 (2007). 10.1016/j.surneu.2006.08.077 (Pubitemid 46734150)
16. P. H. Pevsner, J. W. Eichenbaum, D. C. Miller, G. Pivawer, K. D. Eichenbaum, A. Stern, K. L. Zakian, and J. A. Koutcher, A photothrombotic model of small early ischemic infarcts in the rat brain with histologic and MRI correlation., J. Pharmacol. Toxicol. 45, 227-233 (2001). 10.1016/S1056-8719(01) 00153-8 (Pubitemid 34033693)
17. S. T. Carmichael, Rodent models of focal stroke: size, mechanism, and purpose., NeuroRx 2, 396-409 (2005). 10.1602/neurorx.2.3.396 (Pubitemid 41444874)
18. A. K. Dunn, H. Bolay, M. A. Moskowitz, and D. A. Boas, Dynamic imaging of cerebral blood flow using laser speckle., J. Cerebr. Blood Flow Meth. 21, 195-201 (2001). 10.1097/00004647-200103000-00002 (Pubitemid 32207418)
19. B. Choi, J. C. Ramirez-San-Juan, and J. Lotfi, Linear response range characterization and in vivo application of laser speckle imaging of blood flow dynamics., J. Biomed. Opt. 11, 041129-1-7 (2006). 10.1117/1.2341196 (Pubitemid 44803749)
20. R. O. Bude and J. M. Rubin, Relationship between the resistive index and vascular compliance and resistance., Radiology 211, 411-417 (1999). (Pubitemid 29206809)
21. B. Rao, W. Jia, L. Yu, B. Choi, R. M. Kurtz, J. S. Nelson, and Z. Chen, Spectral Doppler imaging of micro-vasculature response to laser irradiation., Proc. SPIE 7168, 71681T (2009).