Volatile biomarkers of Pseudomonas aeruginosa in cystic fibrosis and noncystic fibrosis bronchiectasis

Letters in Applied Microbiology

Volumn 52, Issue 6, 2011, Pages 610-613

  Savelev, S U ^a   Perry, J D ^b   Bourke, S J ^c   Jary, H ^a   Taylor, R ^a   Fisher, A J ^a   Corris, P A ^a   Petrie, M ^a   De Soyza, A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b FREEMAN HOSPITAL   (United Kingdom)

^c ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

2 nonanone; Analyzerpro; Nonintrusive diagnostic; Pseudomonas aeruginosa; Solid phase micro extraction

Indexed keywords

BACTERIA; DIAGNOSIS; EXTRACTION; GAS CHROMATOGRAPHY; MASS SPECTROMETRY;

2-NONANONE; ANALYZERPRO; CYSTIC FIBROSIS; GOLD STANDARDS; HEADSPACE GAS; HEADSPACES; NON-INTRUSIVE DIAGNOSTICS; PS. AERUGINOSA; PSEUDOMONAS AERUGINOSA; SOLID-PHASE MICROEXTRACTION;

VOLATILE ORGANIC COMPOUNDS;

1 HEPTENE; 2 NONANONE; 2,4 DIMETHYL 1 HEPTENE; ISOPENTYL ALCOHOL; LIMONENE; UNCLASSIFIED DRUG; VOLATILE ORGANIC COMPOUND;

BACTERIUM; BIOCHEMICAL COMPOSITION; MASS SPECTROMETRY; SAMPLING; VOLATILE ORGANIC COMPOUND;

ACHROMOBACTER XYLOSOXIDANS; ARTICLE; BACTERIUM DETECTION; BRONCHIECTASIS; CYSTIC FIBROSIS; ESCHERICHIA COLI; HAEMOPHILUS INFLUENZAE; HUMAN; MAJOR CLINICAL STUDY; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; MORAXELLA CATARRHALIS; MORGANELLA MORGANII; NONCYSTIC FIBROSIS BRONCHIECTASIS; NONHUMAN; PROTEUS MIRABILIS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; SENSITIVITY AND SPECIFICITY; SOLID PHASE MICROEXTRACTION; SPUTUM CULTURE; STAPHYLOCOCCUS AUREUS; STENOTROPHOMONAS MALTOPHILIA; STREPTOCOCCUS PNEUMONIAE;

PSEUDOMONAS AERUGINOSA;

EID: 79955946752     PISSN: 02668254     EISSN: 1472765X     Source Type: Journal    
DOI: 10.1111/j.1472-765X.2011.03049.x     Document Type: Article

References (9)

1. Enderby, B., Smith, D., Carroll, W. and Lenney, W. (2009) Hydrogen cyanide as a biomarker for Pseudomonas aeruginosa in the breath of children with cystic fibrosis. Pediatr Pulmonol 44, 142-147.
2. Health Protection Agency (2009). Investigation of bronchoalveolar lavage, sputum and associated specimens. National Standard Method BSOP 57 Issue 2.3. Available at: .
3. Labows, J.N., McGinley, K.J., Webster, G.F. and Leyden, J.J. (1980) Headspace analysis of volatile metabolites of Pseudomonas aeruginosa and related species by gas chromatography-mass spectrometry. J Clin Microbiol 12, 521-526.
4. Phillips, M., Cataneo, R.N., Condos, R., Ring Erickson, G.A., Greenberg, J., La Bombardi, V., Munawar, M.I. and Tietje, O. (2007) Volatile biomarkers of pulmonary tuberculosis in the breath. Tuberculosis 87, 44-52.
5. Ratjen, F. (2006) Treatment of early Pseudomonas aeruginosa infection in patients with cystic fibrosis. Curr Opin Pulm Med 12, 428-432.
6. Robroeks, C.M., van Berkel, J.J., Dallinga, J.W., Jöbsis, Q., Zimmermann, L.J., Hendriks, H.J., Wouters, M.F., van der Grinten, C.P. et al. (2010) Metabolomics of volatile organic compounds in cystic fibrosis patients and controls. Pediatr Res 68, 75-80.
7. Vogelberg, C., Hirsch, T., Rosen-Wolff, A., Kerkmann, M.L. and Leupold, W. (2003) Pseudomonas aeruginosa and Burkholderia cepacia cannot be detected by PCR in the breath condensate of patients with cystic fibrosis. Pediatr Pulmonol 36, 348-352.
8. Zechman, J.M. and Labows, J.N. Jr (1985) Volatiles of Pseudomonas aeruginosa and related species by automated headspace concentration-gas chromatography. Can J Microbiol 31, 232-237.
9. Zimmermann, D., Hartmann, M., Moyer, M.P., Nolte, J. and Baumbachv, J.I. (2007) Determination of volatile products of human colon cell line metabolism by GC/MS analysis. Metabolomics 3, 13-17.