Aggressive approach to acinar cell carcinoma of the pancreas: A single-institution experience and a literature review

Langenbeck's Archives of Surgery

Volumn 396, Issue 3, 2011, Pages 363-369

  Butturini, Giovanni ^a   Pisano, Michele ^a   Scarpa, Aldo ^b   D'Onofrio, Mirko ^b   Auriemma, Alessandra ^b   Bassi, Claudio ^a  

^a UNIVERSITY HOSPITAL OF VERONA   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

Acinar cell carcinoma; Chemotherapy; Multimodality treatment; Pancreas; Surgical treatment

Indexed keywords

CAPECITABINE; CISPLATIN; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; GEMCITABINE; OXALIPLATIN;

ACINAR CELL CARCINOMA; ADULT; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CARCINOMATOSIS; CHEMOEMBOLIZATION; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PANCREAS CARCINOMA; PANCREAS FISTULA; PANCREAS RESECTION; PANCREATICODUODENECTOMY; PATIENT IDENTIFICATION; PNEUMONIA; PRIORITY JOURNAL; PROGNOSIS; RADIOFREQUENCY ABLATION; RETROSPECTIVE STUDY; SMALL INTESTINE OBSTRUCTION; SURVIVAL TIME;

ADULT; AGED; BIOPSY, NEEDLE; CARCINOMA, ACINAR CELL; CHEMOTHERAPY, ADJUVANT; COHORT STUDIES; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; EARLY DETECTION OF CANCER; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEOPLASM STAGING; PANCREATECTOMY; PANCREATIC NEOPLASMS; RADIOTHERAPY, ADJUVANT; RARE DISEASES; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 79955929876     PISSN: 14352443     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00423-010-0706-2     Document Type: Article

References (24)

1. Chen J, Baithum SI (1985) Morphological study of 391 cases of exocrine pancreatic tumours with special reference to the classification of exocrine pancreatic carcinoma. J Pathol 146:17-29 (Pubitemid 15041572)
2. Cubilla AL, Fitzgerald PJ (1975) Morphological patterns of primary nonendocrine human pancreas. Cancer Res 35:2234-2238
3. Cubilla AL, Fitzgerald PJ (1979) Cancer of the pancreas (nonendocrine): a suggested morphological classification. Semin Oncol 6:285-297 (Pubitemid 10199699)
4. Morohoshi T, Held G, Kloppel G (1983) Exocrine pancreatic tumours and their histological classification: a study based on 167 autopsy and 97 surgical cases. Histopathology 7(5):645-661 (Pubitemid 13048181)
5. Ordonez NG (2001) Pancreatic acinar cell carcinoma. Adv Anat Pathol 8(3):144-159
6. Basturk O, Zamboni G, Klimstra DS et al (2007) Intraductal and papillary variants of acinar cell carcinomas. Am J Surg Pathol 31:363-370
7. Holen KD, Klimstra DS, Hummer A et al (2002) Clinical characteristic and outcomes from an institutional series of acinar cell carcinoma of the pancreas and related tumours. J Clin Oncol 20:4673-4678 (Pubitemid 36025284)
8. Seth AK, Argani P, Campbell KA et al (2008) Acinar cell carcinoma of the pancreas: an institutional series of resected patients and review of the current literature. J Gastrointestinal Surg 12(6):1061-1067
9. Kitagami H, Kondo S, Hirano S et al (2007) Acinar cell carcinoma of the pancreas. Clinical analysis of 115 patients from Pancreatic Cancer Registry of Japan Pancreas Society. Pancreas 35:42-46
10. Klimstra DS, Heffess CS, Oertel JE, Rosai J (1992) Acinar cell carcinoma of the pancreas. A clinicopathologic study of 28 cases. Am J Surg Pathol 16:815-837
11. Cingolani N, Shaco-Levy R, Farruggio A et al (2000) Alpha-fetoprotein production by pancreatic tumours exhibiting acinar cell differentiation: study of five cases, one arising in a mediastinal teratoma. Hum Pathol 31(8):938-944
12. Eriguchi N, Aoyagi S, Hara M et al (2000) Large acinar cell carcinoma of the pancreas in a patient with elevated serum AFP level. L Hepatobiliary Pancreatic Surg 7(2):222-225
13. Chen CP, Chao Y, Li CP et al (2001) Concurrent chemoradiation is effective in the treatment of alpha-fetoprotein-producing acinar cell carcinoma of the pancreas: report of a case. Pancreas 22:326-329 (Pubitemid 32242501)
14. Solcia E, Capella C, Kloppel G (1997) Tumours of the exocrine pancreas. In: Rosai J, Sorbin L (eds) Atlas of tumour pathology. Armed Forces Institute of Pathology (3rd series, fasc. 20), Washington, DC, pp 31-144
15. Tatli S, Mortele KJ, Levy AD et al (2005) CT and MRI features of pure acinar cell carcinoma. Am J Roentgenol 184(2):511-519
16. Chiou YY, Chiang Jh, Hwang JI et al (2004) Acinar cell carcinoma of the pancreas: clinical and computer tomography manifestation. J Comput Assist Tomogr 28(2):180-186
17. D'Onofrio M, Mansueto G, Falconi M et al (2004) Neuroendocrine pancreatic tumour: value of contrast enhanced ultrasonography. Abdom Imaging 29(2):246-258 (Pubitemid 38365018)
18. Schmidt CM, Matos JM, Bentrem DJ et al (2008) Acinar cell carcinoma of the pancreas in the United States: prognostic factors and comparison to ductal adenocarcinoma. J Gastrointest Surg 12:2078-2086
19. Matos JM, Schmidt CM, Turrini O et al (2009) Pancreatic acinar cell carcinoma: a multi-institutional study. J Gastrointest Surg 13 (8):1495-1502
20. Wisnoski NC, Townsend CM Jr, Nealon WH et al (2008) 672 patients with acinar cell carcinoma of the pancreas: a population-based comparison to pancreatic adenocarcinoma. Surgery 144:141-148
21. Lee JL, Kim TW, Chang HMet al (2003) Locally advanced acinar cell carcinoma of the pancreas successfully treated by capecitabine and concurrent radiotherapy: report of two cases. Pancreas 27:e18-e22
22. Kobayashi S, Ishikawa O, Ohigashi H et al (2001) Acinar cell carcinoma of the pancreas treated by en bloc resection and intraperitoneal chemotherapy for peritoneal relapse: a case report of a 15-year survivor. Pancreas 23:109-112 (Pubitemid 32592084)
23. Antoine M, Khitrik-Palchuk M, Saif MW (2007) Long-term survival in a patient with acinar cell carcinoma of the pancreas. A case report and review of literature. J Pancreas 8(6):783-789 (Pubitemid 350200197)
24. Abraham SC, Wu TT, Hruban RH et al (2002) Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: frequent allelic loss of chromosome 11p and alterations in APC/betasecretion pathway. Am J Pathol 160(3):953-962 (Pubitemid 34224584)