-
1
-
-
60649090430
-
Sustained-release oral dalfampridine in multiple sclerosis: A randomised, double-blind, controlled trial
-
Goodman, A.D., Brown, T.R., Krupp, L.B. et al. Sustained-release oral dalfampridine in multiple sclerosis: A randomised, double-blind, controlled trial. Lancet 2009, 373(9665): 732-8.
-
(2009)
Lancet
, vol.373
, Issue.9665
, pp. 732-738
-
-
Goodman, A.D.1
Brown, T.R.2
Krupp, L.B.3
-
2
-
-
84878741581
-
-
http://www.nationalmssociety.org/about-multiple-sclerosis.
-
-
-
-
3
-
-
12344297545
-
The use of 4-aminopyridine (dalfampridine) in demyelinating disorders
-
Hayes, K.C. The use of 4-aminopyridine (dalfampridine) in demyelinating disorders. CNS Drug Rev 2004, 10(4): 295-316.
-
(2004)
CNS Drug Rev
, vol.10
, Issue.4
, pp. 295-316
-
-
Hayes, K.C.1
-
4
-
-
33646776060
-
v channels and effects of symptomatic treatment
-
DOI 10.1016/j.pharmthera.2005.10.006, PII S0163725805002287
-
Judge, S.I., Bever, C.T. Jr. Potassium channel blockers in multiple sclerosis: Neuronal Kv channels and effects of symptomatic treatment. Pharmacol Ther 2006, 111(1): 224-59. (Pubitemid 43765538)
-
(2006)
Pharmacology and Therapeutics
, vol.111
, Issue.1
, pp. 224-259
-
-
Judge, S.I.V.1
Bever Jr., C.T.2
-
5
-
-
0037380712
-
Pharmacokinetics of an immediate-release oral formulation of fampridine (4-aminopyridine) in normal subjects and patients with spinal cord injury
-
DOI 10.1177/0091270003251388
-
Hayes, K.C., Katz, M.A., Devane, J.G., Hsieh, J.T., Wolfe, D.L., Potter, P.J., Blight, A.R. Pharmacokinetcis of an immediate-release oral formulation of fampridine (4-aminopyridine) in normal subjects and patients with spinal cord injury. J Clin Pharmacol 2003, 43(4): 379-85. (Pubitemid 36368779)
-
(2003)
Journal of Clinical Pharmacology
, vol.43
, Issue.4
, pp. 379-385
-
-
Hayes, K.C.1
Katz, M.A.2
Devane, J.G.3
Hsieh, J.T.C.4
Wolfe, D.L.5
Potter, P.J.6
Blight, A.R.7
-
6
-
-
52949119587
-
Sustained-release dalfampridine for symptomatic treatment of multiple sclerosis
-
Korenke, A., Rivey, M., Allington, D. Sustained-release dalfampridine for symptomatic treatment of multiple sclerosis. Ann Pharmacother 2008, 42(10): 1458-65.
-
(2008)
Ann Pharmacother
, vol.42
, Issue.10
, pp. 1458-1465
-
-
Korenke, A.1
Rivey, M.2
Allington, D.3
-
7
-
-
75749141726
-
Single-dose pharmacokinetics of sustained-release fampridine (fampridine-SR) in healthy volunteers and adults with renal impairment
-
Smith, W., Swan, S., Marbury, T., Henney, H. 3rd. Single-dose pharmacokinetics of sustained-release fampridine (fampridine-SR) in healthy volunteers and adults with renal impairment. J Clin Pharmacol 2010, 50(2): 151-9.
-
(2010)
J Clin Pharmacol
, vol.50
, Issue.2
, pp. 151-159
-
-
Smith, W.1
Swan, S.2
Marbury, T.3
Henney III, H.4
-
8
-
-
8944224632
-
The pharmacokinetics and tolerability of a slow-release formulation of 4-aminopyridine in multiple sclerosis patients
-
Bever, C.T. Jr., Young, D., Tierney, D. et al. The pharmacokinetics and tolerability of a slow-release formulation of 4-aminopyridine in multiple sclerosis patients. Neurology 1995, 45(Suppl. 4): A35-42.
-
(1995)
Neurology
, vol.45
, Issue.SUPPL. 4
-
-
Bever Jr., C.T.1
Young, D.2
Tierney, D.3
-
9
-
-
0020508919
-
Effects of 4-aminopyridine in patients with multiple sclerosis
-
DOI 10.1016/0022-510X(83)90145-4
-
Jones, R.E., Heron, J.R., Foster, D.H., Snelgar, R.S., Mason, R.J. Effects of 4-aminopyridine in patients with multiple sclerosis. J Neurol Sci 1983, 60(3): 353-62. (Pubitemid 13051185)
-
(1983)
Journal of the Neurological Sciences
, vol.60
, Issue.3
, pp. 353-362
-
-
Jones, R.E.1
Heron, J.R.2
Foster, D.H.3
-
10
-
-
0025253455
-
Orally administered 4-aminopyridine improves clinical signs in multiple sclerosis
-
Davis, F.A., Stefoski, D., Rush, J. Orally administered 4-aminopyridine improves clinical signs in multiple sclerosis. Ann Neurol 1990, 27(2): 186-92. (Pubitemid 20086640)
-
(1990)
Annals of Neurology
, vol.27
, Issue.2
, pp. 186-192
-
-
Davis, F.A.1
Stefoski, D.2
Rush, J.3
-
11
-
-
0023134727
-
4-Aminopyridine improves clinical signs in multiple sclerosis
-
Stefoski, D., Davis, F.A., Faut, M., Schauf, C.L. 4-Aminopyridine improves clinical signs in multiple sclerosis. Ann Neurol 1987, 21(1): 71-7.
-
(1987)
Ann Neurol
, vol.21
, Issue.1
, pp. 71-77
-
-
Stefoski, D.1
Davis, F.A.2
Faut, M.3
Schauf, C.L.4
-
12
-
-
0028245456
-
The effects of 4-aminopyridine in multiple sclerosis patients: Results of a randomized, placebo-controlled, double-blind, concentration-controlled, crossover trial
-
Bever, C.T., Young, D., Anderson, P.A. et al. The effects of 4-aminopyridine in multiple sclerosis patients: Results of a randomized, placebo-controlled, crossover trial. Neurology 1994, 44(6): 1054-9. (Pubitemid 24188176)
-
(1994)
Neurology
, vol.44
, Issue.6
, pp. 1054-1059
-
-
Bever Jr., C.T.1
Young, D.2
Anderson, P.A.3
Krumholz, A.4
Conway, K.5
Leslie, J.6
Eddington, N.7
Plaisance, K.I.8
Panitch, H.S.9
Dhib-Jalbut, S.10
Fossler, M.J.11
Devane, J.12
Johnson, K.P.13
-
13
-
-
0030989459
-
Quantitative assessment of extended-release 4-aminopyridine for symptomatic treatment of multiple sclerosis
-
Schwid, S.R., Petrie, M.D., McDermott, M.P., Tierney, D.S., Mason, D.H., Goodman, A.D. Quantitative assessment of extended-release 4-aminopyridine for symptomatic treatment of multiple sclerosis. Neurology 1997, 48(4): 817-21.
-
(1997)
Neurology
, vol.48
, Issue.4
, pp. 817-821
-
-
Schwid, S.R.1
Petrie, M.D.2
McDermott, M.P.3
Tierney, D.S.4
Mason, D.H.5
Goodman, A.D.6
-
14
-
-
0037435521
-
Measuring the impact of MS on walking ability: The 12-item MS Walking Scale (MSWS-12)
-
Hobart, J.C., Riazi, A., Lamping, D.L., Fitzpatrick, R., Thompson, A.J. Measuring the Impact of MS on walking ability: The 12-Item MS Walking Scale (MSWS-12). Neurology 2003, 60(1): 31-6. (Pubitemid 36070640)
-
(2003)
Neurology
, vol.60
, Issue.1
, pp. 31-36
-
-
Hobart, J.C.1
Riazi, A.2
Lamping, D.L.3
Fitzpatrick, R.4
Thompson, A.J.5
-
15
-
-
79955899375
-
Sustained-release fampridine consistently improves walking speed and leg strength in multiple sclerosis: A phase 3 trial
-
Goodman, A.D., Schwid, S.R., Brown, T.R. et al. Sustained-release fampridine consistently improves walking speed and leg strength in multiple sclerosis: A phase 3 trial. Mult Scler 2008, 14(Suppl. 1): S298.
-
(2008)
Mult Scler
, vol.14
, Issue.SUPPL. 1
-
-
Goodman, A.D.1
Schwid, S.R.2
Brown, T.R.3
-
16
-
-
84878680241
-
-
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm198463.htm
-
-
-
-
17
-
-
78651366173
-
Interim analysis of open-label extension studies of dalfampridine extended release tablets in patients with multiple sclerosis
-
Goodman, A.D., Brown, T.R., Edwards, K.R. et al. Interim analysis of open-label extension studies of dalfampridine extended release tablets in patients with multiple sclerosis. Neurology 2010, 74(Suppl. 2): A101.
-
(2010)
Neurology
, vol.74
, Issue.SUPPL. 2
-
-
Goodman, A.D.1
Brown, T.R.2
Edwards, K.R.3
-
18
-
-
84878742012
-
Characteristics of walking speed improvement observed in three well controlled studies of dalfampridine extended release tablets 10 mg bid in patients with multiple sclerosis
-
Goodman, A.D., Brown, T.R., Edwards, K. et al. Characteristics of walking speed improvement observed in three well controlled studies of dalfampridine extended release tablets 10 mg bid in patients with multiple sclerosis. Neurology 2010, 74(Suppl. 2): A99.
-
(2010)
Neurology
, vol.74
, Issue.SUPPL. 2
-
-
Goodman, A.D.1
Brown, T.R.2
Edwards, K.3
-
19
-
-
84878706725
-
Response to treatment with dalfampridine extended release tablets in patients with multiple sclerosis is independent of baseline
-
on behalf of the MS-F202, MS-F203, and MS-F204 Study Groups.
-
Brown, T., Edwards, K., Goodman, A. et al., on behalf of the MS-F202, MS-F203, and MS-F204 Study Groups. Response to treatment with dalfampridine extended release tablets in patients with multiple sclerosis is independent of baseline. Neurology 2010, 74(Suppl. 2): A543.
-
(2010)
Neurology
, vol.74
, Issue.SUPPL. 2
-
-
Brown, T.1
Edwards, K.2
Goodman, A.3
|