메뉴 건너뛰기




Volumn 9, Issue , 2011, Pages

Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274

Author keywords

[No Author keywords available]

Indexed keywords

N (3 CHLOROPHENYL) 3 [3,5 DIMETHYL 4 (4 METHYL 1 PIPERAZINYLCARBONYL) 1H PYRROL 2 YLMETHYLENE] 2,3 DIHYDRO N METHYL 2 OXO 1H INDOLE 5 SULFONAMIDE; PROTEIN TYROSINE KINASE; SCATTER FACTOR RECEPTOR; ((3Z) N (3 CHLOROPHENYL) 3 ((3,5 DIMETHYL 4 ((4 METHYLPIPERAZIN 1 YL)CARBONYL) 1H PYRROL 2 YL)METHYLENE) N METHYL 2 OXO 2,3 DIHYDRO 1H INDOLE 5 SULFONAMIDE); ((3Z)-N-(3-CHLOROPHENYL)-3-((3,5-DIMETHYL-4-((4-METHYLPIPERAZIN-1-YL)CARBONYL)-1H-PYRROL-2-YL)METHYLENE)-N-METHYL-2-OXO-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE); INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PROTEIN KINASE INHIBITOR; SULFONAMIDE;

EID: 79955897803     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-9-64     Document Type: Article
Times cited : (24)

References (37)
  • 4
    • 0036169277 scopus 로고    scopus 로고
    • High-dose chemotherapy in soft tissue sarcoma in children
    • 10.1016/S1040-8428(01)00155-X, 11856594
    • Atra A, Pinkerton R. High-dose chemotherapy in soft tissue sarcoma in children. Crit Rev Oncol Hematol 2002, 41:191-196. 10.1016/S1040-8428(01)00155-X, 11856594.
    • (2002) Crit Rev Oncol Hematol , vol.41 , pp. 191-196
    • Atra, A.1    Pinkerton, R.2
  • 5
    • 24644440084 scopus 로고    scopus 로고
    • Rhabdomyosarcoma: new windows of opportunity
    • 10.1634/theoncologist.10-7-518, 16079319
    • Breitfeld PP, Meyer WH. Rhabdomyosarcoma: new windows of opportunity. Oncologist 2005, 10:518-527. 10.1634/theoncologist.10-7-518, 16079319.
    • (2005) Oncologist , vol.10 , pp. 518-527
    • Breitfeld, P.P.1    Meyer, W.H.2
  • 6
    • 14644406812 scopus 로고    scopus 로고
    • Ifosfamide, carboplatin, and etoposide (ICE) reinduction chemotherapy in a large cohort of children and adolescents with recurrent/refractory sarcoma: the Children's Cancer Group (CCG) experience
    • 10.1002/pbc.20227, 15503297
    • Van Winkle P, Angiolillo A, Krailo M, Cheung YK, Anderson B, Davenport V, Reaman G, Cairo MS. Ifosfamide, carboplatin, and etoposide (ICE) reinduction chemotherapy in a large cohort of children and adolescents with recurrent/refractory sarcoma: the Children's Cancer Group (CCG) experience. Pediatr Blood Cancer 2005, 44:338-347. 10.1002/pbc.20227, 15503297.
    • (2005) Pediatr Blood Cancer , vol.44 , pp. 338-347
    • Van Winkle, P.1    Angiolillo, A.2    Krailo, M.3    Cheung, Y.K.4    Anderson, B.5    Davenport, V.6    Reaman, G.7    Cairo, M.S.8
  • 7
    • 33748474046 scopus 로고    scopus 로고
    • Analysis of prognostic factors in patients with nonmetastatic rhabdomyosarcoma treated on intergroup rhabdomyosarcoma studies III and IV: the Children's Oncology Group
    • 10.1200/JCO.2005.05.3801, 16921036
    • Meza JL, Anderson J, Pappo AS, Meyer WH. Analysis of prognostic factors in patients with nonmetastatic rhabdomyosarcoma treated on intergroup rhabdomyosarcoma studies III and IV: the Children's Oncology Group. J Clin Oncol 2006, 24:3844-3851. 10.1200/JCO.2005.05.3801, 16921036.
    • (2006) J Clin Oncol , vol.24 , pp. 3844-3851
    • Meza, J.L.1    Anderson, J.2    Pappo, A.S.3    Meyer, W.H.4
  • 8
    • 65249122512 scopus 로고    scopus 로고
    • Novel therapeutic inhibitors of the c-Met signaling pathway in cancer
    • 10.1158/1078-0432.CCR-08-1306, 19318488
    • Eder JP, Vande Woude GF, Boerner SA, LoRusso PM. Novel therapeutic inhibitors of the c-Met signaling pathway in cancer. Clin Cancer Res 2009, 15:2207-2214. 10.1158/1078-0432.CCR-08-1306, 19318488.
    • (2009) Clin Cancer Res , vol.15 , pp. 2207-2214
    • Eder, J.P.1    Vande Woude, G.F.2    Boerner, S.A.3    LoRusso, P.M.4
  • 9
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    • 10.1038/nm0596-561, 8616716
    • Druker BJ, Tamura S, Buchdunger E, Ohno S, Segal GM, Fanning S, Zimmermann J, Lydon NB. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996, 2:561-566. 10.1038/nm0596-561, 8616716.
    • (1996) Nat Med , vol.2 , pp. 561-566
    • Druker, B.J.1    Tamura, S.2    Buchdunger, E.3    Ohno, S.4    Segal, G.M.5    Fanning, S.6    Zimmermann, J.7    Lydon, N.B.8
  • 10
    • 38949178846 scopus 로고    scopus 로고
    • Favorable long-term follow-up results over 6 years for response, survival, and safety with imatinib mesylate therapy in chronic-phase chronic myeloid leukemia after failure of interferon-alpha treatment
    • 10.1182/blood-2007-07-103523, 17932248
    • Hochhaus A, Druker B, Sawyers C, Guilhot F, Schiffer CA, Cortes J, Niederwieser DW, Gambacorti-Passerini C, Stone RM, Goldman J, et al. Favorable long-term follow-up results over 6 years for response, survival, and safety with imatinib mesylate therapy in chronic-phase chronic myeloid leukemia after failure of interferon-alpha treatment. Blood 2008, 111:1039-1043. 10.1182/blood-2007-07-103523, 17932248.
    • (2008) Blood , vol.111 , pp. 1039-1043
    • Hochhaus, A.1    Druker, B.2    Sawyers, C.3    Guilhot, F.4    Schiffer, C.A.5    Cortes, J.6    Niederwieser, D.W.7    Gambacorti-Passerini, C.8    Stone, R.M.9    Goldman, J.10
  • 12
    • 33745006872 scopus 로고    scopus 로고
    • Predictive factors for interstitial lung disease, antitumor response, and survival in non-small-cell lung cancer patients treated with gefitinib
    • 10.1200/JCO.2005.04.9866, 16735708
    • Ando M, Okamoto I, Yamamoto N, Takeda K, Tamura K, Seto T, Ariyoshi Y, Fukuoka M. Predictive factors for interstitial lung disease, antitumor response, and survival in non-small-cell lung cancer patients treated with gefitinib. J Clin Oncol 2006, 24:2549-2556. 10.1200/JCO.2005.04.9866, 16735708.
    • (2006) J Clin Oncol , vol.24 , pp. 2549-2556
    • Ando, M.1    Okamoto, I.2    Yamamoto, N.3    Takeda, K.4    Tamura, K.5    Seto, T.6    Ariyoshi, Y.7    Fukuoka, M.8
  • 14
    • 19644395911 scopus 로고    scopus 로고
    • HGF/SF-Met signaling in tumor progression
    • 10.1038/sj.cr.7290264, 15686627
    • Gao CF, Vande Woude GF. HGF/SF-Met signaling in tumor progression. Cell Res 2005, 15:49-51. 10.1038/sj.cr.7290264, 15686627.
    • (2005) Cell Res , vol.15 , pp. 49-51
    • Gao, C.F.1    Vande Woude, G.F.2
  • 15
    • 67649393456 scopus 로고    scopus 로고
    • MET pathway as a therapeutic target
    • 10.1097/JTO.0b013e31819d6f91, 2664527, 19333071
    • Kim ES, Salgia R. MET pathway as a therapeutic target. J Thorac Oncol 2009, 4:444-447. 10.1097/JTO.0b013e31819d6f91, 2664527, 19333071.
    • (2009) J Thorac Oncol , vol.4 , pp. 444-447
    • Kim, E.S.1    Salgia, R.2
  • 16
    • 43749091506 scopus 로고    scopus 로고
    • Showering c-MET-dependent cancers with drugs
    • 10.1016/j.gde.2008.02.001, 18406132
    • Knudsen BS, Vande Woude G. Showering c-MET-dependent cancers with drugs. Curr Opin Genet Dev 2008, 18:87-96. 10.1016/j.gde.2008.02.001, 18406132.
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 87-96
    • Knudsen, B.S.1    Vande Woude, G.2
  • 17
    • 13944276728 scopus 로고    scopus 로고
    • Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer
    • 10.1158/0008-5472.CAN-04-2650, 15735036
    • Ma PC, Jagadeeswaran R, Jagadeesh S, Tretiakova MS, Nallasura V, Fox EA, Hansen M, Schaefer E, Naoki K, Lader A, et al. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res 2005, 65:1479-1488. 10.1158/0008-5472.CAN-04-2650, 15735036.
    • (2005) Cancer Res , vol.65 , pp. 1479-1488
    • Ma, P.C.1    Jagadeeswaran, R.2    Jagadeesh, S.3    Tretiakova, M.S.4    Nallasura, V.5    Fox, E.A.6    Hansen, M.7    Schaefer, E.8    Naoki, K.9    Lader, A.10
  • 18
    • 51749095291 scopus 로고    scopus 로고
    • Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion
    • 10.1111/j.1525-1438.2007.01135.x, 18021219
    • Koon EC, Ma PC, Salgia R, Welch WR, Christensen JG, Berkowitz RS, Mok SC. Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion. Int J Gynecol Cancer 2008, 18:976-984. 10.1111/j.1525-1438.2007.01135.x, 18021219.
    • (2008) Int J Gynecol Cancer , vol.18 , pp. 976-984
    • Koon, E.C.1    Ma, P.C.2    Salgia, R.3    Welch, W.R.4    Christensen, J.G.5    Berkowitz, R.S.6    Mok, S.C.7
  • 19
    • 54249157471 scopus 로고    scopus 로고
    • Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody
    • 10.1158/0008-5472.CAN-08-1712, 2671680, 18829562
    • Cao L, Yu Y, Darko I, Currier D, Mayeenuddin LH, Wan X, Khanna C, Helman LJ. Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody. Cancer Res 2008, 68:8039-8048. 10.1158/0008-5472.CAN-08-1712, 2671680, 18829562.
    • (2008) Cancer Res , vol.68 , pp. 8039-8048
    • Cao, L.1    Yu, Y.2    Darko, I.3    Currier, D.4    Mayeenuddin, L.H.5    Wan, X.6    Khanna, C.7    Helman, L.J.8
  • 20
    • 66949167418 scopus 로고    scopus 로고
    • Immunohistochemical detection of EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics
    • 10.1111/j.1365-2559.2009.03303.x, 19469909
    • Grass B, Wachtel M, Behnke S, Leuschner I, Niggli FK, Schafer BW. Immunohistochemical detection of EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics. Histopathology 2009, 54:873-879. 10.1111/j.1365-2559.2009.03303.x, 19469909.
    • (2009) Histopathology , vol.54 , pp. 873-879
    • Grass, B.1    Wachtel, M.2    Behnke, S.3    Leuschner, I.4    Niggli, F.K.5    Schafer, B.W.6
  • 23
    • 77955592758 scopus 로고    scopus 로고
    • Rhabdomyosarcoma of the head and neck: a clinicopathological and immunohistochemical analysis of 29 cases
    • 10.1590/S0103-64402010000100011, 20464324
    • Andrade CR, Takahama Junior A, Nishimoto IN, Kowalski LP, Lopes MA. Rhabdomyosarcoma of the head and neck: a clinicopathological and immunohistochemical analysis of 29 cases. Braz Dent J 2010, 21:68-73. 10.1590/S0103-64402010000100011, 20464324.
    • (2010) Braz Dent J , vol.21 , pp. 68-73
    • Andrade, C.R.1    Takahama Junior, A.2    Nishimoto, I.N.3    Kowalski, L.P.4    Lopes, M.A.5
  • 24
    • 0034045165 scopus 로고    scopus 로고
    • Expression of HER/erbB family of receptor tyrosine kinases and induction of differentiation by glial growth factor 2 in human rhabdomyosarcoma cells
    • 10.1002/1097-0215(20000701)87:1<29::AID-IJC5>3.0.CO;2-J, 10861449
    • Ricci C, Landuzzi L, Rossi I, De Giovanni C, Nicoletti G, Astolfi A, Pupa S, Menard S, Scotlandi K, Nanni P, Lollini PL. Expression of HER/erbB family of receptor tyrosine kinases and induction of differentiation by glial growth factor 2 in human rhabdomyosarcoma cells. Int J Cancer 2000, 87:29-36. 10.1002/1097-0215(20000701)87:1<29::AID-IJC5>3.0.CO;2-J, 10861449.
    • (2000) Int J Cancer , vol.87 , pp. 29-36
    • Ricci, C.1    Landuzzi, L.2    Rossi, I.3    De Giovanni, C.4    Nicoletti, G.5    Astolfi, A.6    Pupa, S.7    Menard, S.8    Scotlandi, K.9    Nanni, P.10    Lollini, P.L.11
  • 26
    • 0032529257 scopus 로고    scopus 로고
    • Up-regulation of MET but not neural cell adhesion molecule expression by the PAX3-FKHR fusion protein in alveolar rhabdomyosarcoma
    • Ginsberg JP, Davis RJ, Bennicelli JL, Nauta LE, Barr FG. Up-regulation of MET but not neural cell adhesion molecule expression by the PAX3-FKHR fusion protein in alveolar rhabdomyosarcoma. Cancer Res 1998, 58:3542-3546.
    • (1998) Cancer Res , vol.58 , pp. 3542-3546
    • Ginsberg, J.P.1    Davis, R.J.2    Bennicelli, J.L.3    Nauta, L.E.4    Barr, F.G.5
  • 27
    • 33746504571 scopus 로고    scopus 로고
    • Invasive growth: a MET-driven genetic programme for cancer and stem cells
    • 10.1038/nrc1912, 16862193
    • Boccaccio C, Comoglio PM. Invasive growth: a MET-driven genetic programme for cancer and stem cells. Nat Rev Cancer 2006, 6:637-645. 10.1038/nrc1912, 16862193.
    • (2006) Nat Rev Cancer , vol.6 , pp. 637-645
    • Boccaccio, C.1    Comoglio, P.M.2
  • 29
    • 48249133585 scopus 로고    scopus 로고
    • Targeting the c-MET signaling pathway for cancer therapy
    • 10.1517/13543784.17.7.997, 18549337
    • Liu X, Yao W, Newton RC, Scherle PA. Targeting the c-MET signaling pathway for cancer therapy. Expert Opin Investig Drugs 2008, 17:997-1011. 10.1517/13543784.17.7.997, 18549337.
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 997-1011
    • Liu, X.1    Yao, W.2    Newton, R.C.3    Scherle, P.A.4
  • 30
    • 34848855124 scopus 로고    scopus 로고
    • The MET receptor tyrosine kinase in invasion and metastasis
    • 10.1002/jcp.21183, 17607709
    • Benvenuti S, Comoglio PM. The MET receptor tyrosine kinase in invasion and metastasis. J Cell Physiol 2007, 213:316-325. 10.1002/jcp.21183, 17607709.
    • (2007) J Cell Physiol , vol.213 , pp. 316-325
    • Benvenuti, S.1    Comoglio, P.M.2
  • 31
    • 38549115197 scopus 로고    scopus 로고
    • The Met tyrosine kinase receptor in development and cancer
    • 10.1007/s10555-007-9107-6, 18175071
    • Gentile A, Trusolino L, Comoglio PM. The Met tyrosine kinase receptor in development and cancer. Cancer Metastasis Rev 2008, 27:85-94. 10.1007/s10555-007-9107-6, 18175071.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 85-94
    • Gentile, A.1    Trusolino, L.2    Comoglio, P.M.3
  • 32
    • 17344381429 scopus 로고    scopus 로고
    • Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
    • 10.1038/ng0597-68, 9140397
    • Schmidt L, Duh FM, Chen F, Kishida T, Glenn G, Choyke P, Scherer SW, Zhuang Z, Lubensky I, Dean M, et al. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet 1997, 16:68-73. 10.1038/ng0597-68, 9140397.
    • (1997) Nat Genet , vol.16 , pp. 68-73
    • Schmidt, L.1    Duh, F.M.2    Chen, F.3    Kishida, T.4    Glenn, G.5    Choyke, P.6    Scherer, S.W.7    Zhuang, Z.8    Lubensky, I.9    Dean, M.10
  • 33
    • 0033118781 scopus 로고    scopus 로고
    • The role of chimeric paired box transcription factors in the pathogenesis of pediatric rhabdomysarcoma
    • Barr FG. The role of chimeric paired box transcription factors in the pathogenesis of pediatric rhabdomysarcoma. Cancer Res 1999, 59:1711s-1715s.
    • (1999) Cancer Res , vol.59
    • Barr, F.G.1
  • 34
    • 77149136087 scopus 로고    scopus 로고
    • Inhibition of rhabdomyosarcoma's metastatic behavior through downregulation of MET receptor signaling
    • 10.2478/v10042-009-0108-x, 20164036
    • Lukasiewicz E, Miekus K, Kijowski J, Drabik G, Wilusz M, Bobis-Wozowicz S, Majka M. Inhibition of rhabdomyosarcoma's metastatic behavior through downregulation of MET receptor signaling. Folia Histochem Cytobiol 2009, 47:485-489. 10.2478/v10042-009-0108-x, 20164036.
    • (2009) Folia Histochem Cytobiol , vol.47 , pp. 485-489
    • Lukasiewicz, E.1    Miekus, K.2    Kijowski, J.3    Drabik, G.4    Wilusz, M.5    Bobis-Wozowicz, S.6    Majka, M.7
  • 37
    • 66149135285 scopus 로고    scopus 로고
    • The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma
    • 10.1158/0008-5472.CAN-08-2881, 2871252, 19318576
    • Seiwert TY, Jagadeeswaran R, Faoro L, Janamanchi V, Nallasura V, El Dinali M, Yala S, Kanteti R, Cohen EE, Lingen MW, et al. The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma. Cancer Res 2009, 69:3021-3031. 10.1158/0008-5472.CAN-08-2881, 2871252, 19318576.
    • (2009) Cancer Res , vol.69 , pp. 3021-3031
    • Seiwert, T.Y.1    Jagadeeswaran, R.2    Faoro, L.3    Janamanchi, V.4    Nallasura, V.5    El Dinali, M.6    Yala, S.7    Kanteti, R.8    Cohen, E.E.9    Lingen, M.W.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.