Determination of puerarin in rat plasma by rapid resolution liquid chromatography tandem mass spectrometry in positive ionization mode

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 19, 2011, Pages 1497-1501

  Luo, Cheng Feng ^a   Yuan, Mu ^a   Chen, Min Sheng ^a   Liu, Shi Ming ^a   Huang, Bi Yun ^a   Liu, Xia Wen ^a   Zhu, Liu ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Electrospray ionization; Mass spectrometry; Pharmacokinetics; Puerarin; Rapid resolution liquid chromatography; Rats

Indexed keywords

DETECTION LIMITS; HIGHLY SENSITIVE; INTERNAL STANDARDS; INTRAVENOUS ADMINISTRATION; IONIZATION MODES; LINEAR RESPONSE; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MOBILE PHASE; MULTIPLE REACTION MONITORING; PHARMACOKINETIC PARAMETERS; PHARMACOKINETIC STUDIES; PUERARIN; RAPID RESOLUTION; RAT PLASMA; REVERSED-PHASE COLUMNS; TECTORIDIN; VALIDATED METHODS;

ACETIC ACID; COLUMN CHROMATOGRAPHY; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION; MASS SPECTROMETRY; METHANOL; PHARMACOKINETICS; PLASMA (HUMAN); PLASMAS;

LIQUIDS;

ACETIC ACID; METHANOL; PUERARIN; TECTORIGENIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; FEMALE; IONIZATION; MALE; MASS SPECTROMETER; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSED PHASE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION PROCESS;

ANIMALS; CHROMATOGRAPHY, LIQUID; FEMALE; ISOFLAVONES; LEAST-SQUARES ANALYSIS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; VASODILATOR AGENTS;

RATTUS;

EID: 79955891454     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.03.035     Document Type: Article

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