The risk for myocarditis of clozapine and other atypical antipsychotics: Case report and study of the literature;Das myokarditisrisiko einer clozapin-therapie und bei anderen atypischen antipsychotika

Psychiatrische Praxis

Volumn 38, Issue 4, 2011, Pages 201-203

  Adamaszek, Michael ^a   Olbrich, Sebastian ^a   Hegerl, Ulrich ^a   Schönknecht, Peter ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

clozapine; myocarditis; schizoaffective disorder

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; C REACTIVE PROTEIN; CLOZAPINE; CREATINE KINASE; INTERLEUKIN 6; TROPONIN I; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CASE REPORT; DRUG SAFETY; DYSKINESIA; ELECTROCARDIOGRAPHY; EOSINOPHILIA; HUMAN; MYOCARDITIS; NUCLEAR MAGNETIC RESONANCE IMAGING; SCHIZOAFFECTIVE PSYCHOSIS; TREATMENT OUTCOME;

ADULT; ANTIPSYCHOTIC AGENTS; CLOZAPINE; CRISIS INTERVENTION; DANGEROUS BEHAVIOR; DELUSIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALE; MYOCARDITIS; PATIENT ADMISSION; PSYCHOTIC DISORDERS; VENTRICULAR DYSFUNCTION, LEFT;

EID: 79955860752     PISSN: 03034259     EISSN: 14390876     Source Type: Journal    
DOI: 10.1055/s-0030-1266074     Document Type: Article

References (18)

1. Davis J M., Chen N, Glick I D. A meta-analysis of the efficacy of second-generation antipsychotics. Arch Gen Psychiatry 2003 60 553-564 (Pubitemid 36682312)
2. De Hert M, Correll C U., Cohen D. Do antipsychotic medications reduce or increase mortality in schizophrenia? A critical appraisal of the Fin-11 study. Schizophr Res 2010 117 68-74
3. Green A I., Tohen M, Patel J K. et al. Clozapine in the treatment of refractory psychotic mania. Am J Psychiatr 2000 157 982-986 (Pubitemid 30412351)
4. Tiihonen J, Lönnquist J, Wahlbeck K et al. 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet 2009 374 620-627
5. Haas S J., Hill R, Krum H et al. Clozapine-associated myocarditis: a review of 116 cases of suspected myocarditis associated with the use of clozapine in Australia during 19932003. Drug Saf 2007 30 47-57 (Pubitemid 46072357)
6. Hagg S, Spigset O, Bate A et al. Myocarditis related to clozapine treatment. J Clin Psychopharmacol 2001 21 382-388 (Pubitemid 32673027)
7. Kelly D L., McMahon R P., Liu F et al. Cardiovascular disease mortality in patients with chronic schizophrenia treated with clozapine: a retrospective cohort study. J Clin Psychiatry 2010 71 304-311
8. Kilian J G., Kerr K, Lawrence C et al. Myocarditis and cardiomyopathy associated with clozapine. Lancet 1999 354 1841-1845
9. Komossa K, Rummel-Kluge C, Hunger H et al. Zotepine versus other atypical antipsychotics for schizophrenia. Cochr Datab Syst Rev 2010 Art-No: CD006628
10. La Grenade L, Graham D, Trontell A. Myocarditis and cardiomyopathy associated with clozapine use in the United States. N Engl J Med 2001 345 224-225 (Pubitemid 32662140)
11. Merrill D B., William Dec G, Goff D C. Adverse cardiac effects associated with Clozapine. J Clin Psychopharmac 2005 25 32-41 (Pubitemid 40129380)
12. Ray W A., Chung C P., Murray K T. et al. Atypical antipsychotic drugs and the risk of sudden cardiac death. N Engl J Med 2009 360 225-235
13. Coulter D M., Bate A, Meyboom R H. et al. Antipsychotic drugs and heart muscle disorder in international pharmacovigilance: data mining study. BMJ 2001 322 1207-1209 (Pubitemid 32453065)
14. Weinmann S, Read J, Aderhold V. Influence of antipsychotics on mortality in schizophrenia: a systematic review. Schizophr Res 2009 113 1-11
15. Asenjo Lobos C, Komossa K et al. Clozapine versus other atypical antipsychotics for schizophrenia. Cochr Datab Syst Rev 2010 Art-No: CD006633
16. Falkai P, Gaebel W, Weinmann S et al. Behandlungsleitlinie Schizophrenie. Deutsche Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN), Interdisziplinäre S3-Praxisleitlinien 2006 1 1-288
17. NICE Clinical Guideline 82: Schizophrenia. Core interventions in the treatment and management of schizophrenia in adults in primary and secondary care. London National Institute for Health and Clinical Excellence 2009 http://www.nice.org.uk/nicemedia/pdf/CG82QuickRefGuide.pdf
18. Schneeweiss S, Avorn J. Antipsychotic Agents and Sudden Cardia Death How should we manage the risk? N Engl J Med 2009 360 294-296