Design, synthesis, antibacterial and invitro antioxidant activity of substituted 2hbenzopyran-2-one derivatives

International Journal of ChemTech Research

Volumn 3, Issue 2, 2011, Pages 555-559

  Rajasekaran, S ^a   Rao, Gopal Krishna ^a   Sanjay Pai, P N ^a   Ranjan, Amit ^a  

^a AL AMEEN COLLEGE OF PHARMACY   (India)

Author keywords

Antibacterial; Antioxidant; Coumarin

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2 [2 (2H CHROMEN 3 YL) 2 OXOETHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2H BENZOPYRAN 2 ONE DERIVATIVE; ANTIINFECTIVE AGENT; ANTIOXIDANT; BENZOPYRAN DERIVATIVE; CHROMEN SULFANYL DERIVATIVE; COUMARIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONFORMATIONAL TRANSITION; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; INFRARED SPECTROSCOPY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TECHNIQUE;

EID: 79955854671     PISSN: None     EISSN: 09744290     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Brahnbhatt D.I, Gajera J.M, Pandya V.P, Patel M.A. Synthesis of 3-(6-aryl-pyridin-2-yl)-and 8- (6-aryl-pyridin-2-yl)coumarins. Ind J Chem 2007; 46(B): 869-871.
2. Murrey R.D.H, Medez D, Brown S.A. The Natural coumarins occurences. Chemistry and Biochemistry John Wiley Interscience New York 1982.
3. Bourinbaiar A.S, Tan X, Nagomy R. Acta Virol. A facile synthesis of fluorinated 4- hydroxycoumarins 1993; 37: 241-250
4. Tummino PJ, Ferguson D, Hupe D. Biochem Biophys Res Commerce 1994; 201: 290-294.
5. Venugopala K.N, Jayashree B.S. Synthesis and characterization of Schiff bases of aminothiazolyl bromocoumarin for their analgesic and anti-inflammatory activity. Asian J Chem 2004; 16(1): 407-411.
6. Kokotos G, Tzougraki C. Synthesis and study of substituted coumarins. A facile preparation of D, L-o-Tyrosine. J Hetero Chem 1986; 23: 87.
7. Ghantwal S.R, Samant S.D. Claisen rearrangement of 3-bromo-, 3,6-dibromo-,3,8- dibromo-and 8-iodo/aminomethyl/acetyl-7- allyloxy-4-methylcoumarins. Ind J Chem 1999; 38(B): 1242-1247.
8. Majumder P.L, Majumder S. Further evidence for the mechanism of formation of coumarin by perkin reaction from salicylaldehyde and a novel synthesis of 1,1-diphenyl-2(2'- hydroxyphenyl)ethene from O-α,α- diphenylacetylsalicylaldehyde with Et3N. Eur J Med Chem 1993; 28: 572-578
9. Upadhyay K.K, Mishra R.K, Kumar A. A convenient synthesis of some couamrin derivatives using SNCl2.2H2O as catalyst. Catal Lett; 2008; 121: 118-120.
10. Harayama T, Nakatsuka K, Nishioka H, Murakami K, Hayashida N, Ishii H. Convenient synthesis of a simple couamrin from salicylaldehyde and wittig reagent.II: synthesis of bromo-and methoxycarbonylcoumarins. Chem Pharm Bull 1994; 42(10): 2170-2173.
11. Shaabani A, Ghadari R, Rahmati A, Rezayan AH. Coumarin synthesis via Knoevenagel condensation reaction in 1,1,3,3-N,N,N',N'- tetramethylguanidinium trifluoroacetate ionic liquid. J Iran Chem Soc 2009; vol.6(4): 710-14.
12. Patel K.H, Mehta A.G. Synthesis of novel azetidinone and thiazolidinones derivatives and evaluation of their antimicrobial efficacy. J Chem 2006; vol 3(11): 103-109.
13. Mogilaiah K, Sakram B. Microwave assisted synthesis of N-(3-aryl-1,8-naphthyridin-2- yl)phthalimides under solvent-free conditions. Ind J Chem 2007; 46(B): 207-209
14. Lipinski C.A, Lombardo F, Dominy B.W, Feeney P.J, Adv. Drug Deliv. Rev., 1997, 23, 3-25.
15. Barry A.L, The Antimicrobial Susceptibility Test, Principle and Practices, 1999, 4th Edition, ELBS: London, 180.
16. Mensor L.L, Menzes F.S, Leitao G.G, Reis A.S, Dosantos T.C, Coube C.S Phytother. Res., 2001, 15, 127-130.