Population pharmacokinetic investigation of digoxin in Japanese infants and young children

Journal of Clinical Pharmacology

Volumn 51, Issue 6, 2011, Pages 857-863

  Yukawa, Miho ^a   Yukawa, Eiji ^b   Suematsu, Fumihiro ^c   Takiguchi, Takako ^b   Ikeda, Hirohito ^a   Aki, Hatsumi ^a   Mimemoto, Masao ^d  

^a FUKUOKA UNIVERSITY   (Japan)

^b DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^c Yufuin Kosei Nenkin Hospital   (Japan)

^d KYUSHU KOSEI NENKIN HOSPITAL   (Japan)

Author keywords

digoxin; infants and young children; nonlinear mixed effects modeling; population pharmacokinetics

Indexed keywords

DIGOXIN; SPIRONOLACTONE;

ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CHILD; COMPUTER PROGRAM; CONGESTIVE HEART FAILURE; DEMOGRAPHY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFICACY; DRUG ELIMINATION; DRUG MONITORING; ELIXIR; FEMALE; HOSPITALIZED CHILD; HOSPITALIZED INFANT; HUMAN; INFANT; JAPANESE; MAJOR CLINICAL STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MORNING DOSAGE; PHYSICIAN; POWDER; PRESCHOOL CHILD; STEADY STATE;

ASIAN CONTINENTAL ANCESTRY GROUP; CARDIOTONIC AGENTS; CHILD, PRESCHOOL; DIGOXIN; DRUG MONITORING; FEMALE; HEART FAILURE; HUMANS; INFANT; MALE; MODELS, STATISTICAL; NONLINEAR DYNAMICS; PHARMACEUTICAL SOLUTIONS; POWDERS; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES;

EID: 79955852732     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270010374475     Document Type: Article

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