Tiliroside-derivatives enhance GLUT4 translocation via AMPK in muscle cells

Diabetes Research and Clinical Practice

Volumn 92, Issue 2, 2011, Pages

  Shi, Lihuan ^a   Qin, Nan ^a   Hu, Lijuan ^a   Liu, Linjuan ^a   Duan, Hongquan ^a   Niu, Wenyan ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Derivative; Glucose transporter 4; Skeletal muscle cell; Tiliroside; Translocation

Indexed keywords

ADENYLATE KINASE; ANTIDIABETIC AGENT; GLUCOSE TRANSPORTER 4; TILIROSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LEVEL; CELL TRANSPORT; CONTROLLED STUDY; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME ACTIVITY; MYOBLAST; NONHUMAN; PROTEIN TRANSPORT;

ANIMALS; CELL LINE; CELL SURVIVAL; FLAVONOIDS; GLUCOSE TRANSPORTER TYPE 4; HYPOGLYCEMIC AGENTS; MICE; MUSCLE CELLS; PROTEIN TRANSPORT; RATS;

EID: 79955851016     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2011.02.009     Document Type: Article

References (14)

1. Winder W.W., Hardie D.G. AMP-activated protein kinase, a metabolic master switch: possible roles in Type 2 diabetes. Am J Physiol 1999, 277(1 Pt 1):E1-E10.
2. DeFronzo R.A., Jacot E., Jequier E., Maeder E., Wahren J., Felber J.P. The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous characterization. Diabetes 1981, 30(12):1000-1007.
3. Bouzakri K., Koistinen H.A., Zierath J.R. Molecular mechanisms of skeletal muscle insulin resistance in type 2 diabetes. Curr Diabetes Rev 2005, 1(2):167-174.
4. Dohm G.L., Tapscott E.B., Pories W.J., Dabbs D.J., Flickinger E.G., Meelheim D. An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects. J Clin Invest 1988, 82(2):486-494.
5. DeFronzo R.A., Bonadononna R.C., Ferrannini E. Pathogenesis of NIDDM. A balanced overview. Diab Care 1992, 15(3):318-368.
6. Zhao C., Qiao W., Zhang Y., Lu B., Duan H. Study on anti-diabetes active fraction and constituents from Potentilla chinesis. Zhongguo Zhong Yao Za Zhi 2008, 33(6):680-682.
7. Ninomiya K., Matsuda H., Kubo M., Morikawa T., Nishida N., Yoshikawa M. Potent anti-obese principle from Rosa canina: structural requirements and mode of action of trans-tiliroside. Bioorg Med Chem Lett 2007, 17(11):3059-3064.
8. Niu W., Bilan P.J., Ishikura S., et al. Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4myc skeletal muscle cells. Am J Physiol Endcrinol Metab 2010, 298(5):E1058-E1071.
9. Tatsuzaki J., Bastow K.F., Nakagawa-Goto K., Nakamura S., Itokawa H., Lee K.H. Dehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents. J Nat Prod 2006, 69(10):1445-1449.
10. Babu K.S., Li X.C., Jacob M.R., Zhang Q., Khan S.I., Ferreira D., Clark A.M. Synthesis, antifungal activity, and structure-activity relationships of coruscanone A analogues. J Med Chem 2006, 49(26):7877-7886.
11. Niu W., Bilan P.J., Hayashi M., Da Y., Yao Z. Insulin sensitivity and inhibition by forskolin, dipyrodamole and pentobarbital of glucose transport in three L6 muscle cell lines. Sci China C-Life Sci 2007, 50(6):739-747.
12. Niu W., Bilan P.J., Yu J., et al. PKCe{open} regulates contraction-stimulated GLUT4 traffic in skeletal muscle cells. J Cell Physiol 2011, 226(1):173-180.
13. Somwar R., Niu W., Kim D.Y., et al. Differential effects of phosphatidylinositol-3 kinase inhibition on intracellular signals regulating GLUT4 translocation and glucose transport. J Biol Chem 2001, 276(49):46079-46087.
14. Flavonoid derivatives, synthesis and their medicinal purpose, patent PCT- CN2010-001818.