First total synthesis of 5-hydroxy-3-methyl-4-propylsulfanyl-5 h -furan-2-one: A cancer chemopreventive agent

Synthesis

Volumn , Issue 10, 2011, Pages 1595-1598

  Borikar, Sanjay P ^a   Paul, Vincent ^a   Puranik, Vedavati G ^a   Sathe, Vilas T ^a   Lagunas Rivera, Selene ^b   Ordónez, Mario ^b  

^a NATIONAL CHEMICAL LABORATORY   (India)

^b CENTRO DE INVESTIGACIONES QUÍMICAS   (Mexico)

Author keywords

Allium cepa; chemopreventive; Gilman reagent; selective; synthesis

Indexed keywords

ALLIUM CEPA; CHEMOPREVENTIVE; GILMAN REAGENT; SELECTIVE; SYNTHESIS;

FUNCTIONAL GROUPS; ORGANIC POLLUTANTS;

AROMATIC COMPOUNDS;

1 BENZYL 3 (PROPYLTHIO) 1H PYRROLE 2,5 DIONE; 1 BENZYL 3 BROMO 4 (PROPYLTHIO) 1H PYRROLE 2,5 DIONE; 1 BENZYL 3 METHYL 4 (PROPYLTHIO) 1H PYRROLE 2,5 DIONE; 1 BENZYL 3 METHYL 4 BROMO 1H PYRROLE 2,5 DIONE; 1 METHYL 4 (PROPYLTHIO)FURAN 2,5 DIONE; 3 BROMO 1 BENZYL 1H PYRROLE 2,5 DIONE; 5 HYDROXY 3 METHYL 4 PROPYLSULFANYL 5H FURAN 2 ONE; ACID ANHYDRIDE; ANTINEOPLASTIC AGENT; CYCLIC ANHYDRIDE; GILMAN REAGENT; NATURAL PRODUCT; REAGENT; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CRYSTAL STRUCTURE; DRUG DETERMINATION; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 79955833990     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1260004     Document Type: Article

References (13)

1. Sporn M B., Newton D L., Fed. Proc. 1979 38 528
2. Hong W K., Sporn M B., Science 1997 278 1073
3. Wattenberg L W., Cancer Res. 1985 45 1
4. Begleiter A, Leith M K., Curphey T J., Doherty G P., Oncol. Res. 1997 9 371
5. Song L L., Kosmeder J W. II., Lee S K., Gerhäuser C, Lantvit D, Moon R C., Moriarty R M., Pezzuto J M., Cancer Res. 1999 59 578
6. Boone C W., Steele V E., Kelloff G J., Mutat. Res. 1992 267 251
7. Gills J J., Jeffery E H., Matusheski N V., Moon R C., Lantvit D D., Pezzuto J M., Cancer Lett. 2006 236 72
8. Xiao H, Parkin K L., Phytochemistry 2007 68 1059
9. Gomez-Paloma L, Monti M C., Terracciano S, Casapullo A, Riccio R, Curr. Org. Chem. 2005 9 1419
10. Dubernet M, Caubert V, Guillard J, Viaud-Massuard M C., Tetrahedron 2005 61 4585
11. Corey E J., Katzenellenbogen J A., J. Am. Chem. Soc. 1969 91 1851
12. Xie G, Lown J W., Tetrahedron Lett. 1994 35 5555
13. Sheldrick G M., SHELX-97 Program for Crystal Structure Solution and Refinement University of Gottingen Germany 1997