Comparison of intracellular accumulation and cytotoxicity of free mTHPC and mTHPC-loaded PLGA nanoparticles in human colon carcinoma cells

Nanotechnology

Volumn 22, Issue 24, 2011, Pages

  Löw, Karin ^a   Knobloch, Thomas ^b   Wagner, Sylvia ^a   Wiehe, Arno ^c   Engel, Andrea ^d   Langer, Klaus ^d   Briesen, Hagen Von ^a  

^a FRAUNHOFER INSTITUTE FOR BIOMEDICAL ENGINEERING   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c Biolitec AG   (Germany)

^d UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE EFFECT; COLON CARCINOMA CELLS; CONCENTRATION-DEPENDENT; CYTOTOXICITY ASSAYS; DELIVERY SYSTEMS; DRUG CARRIER SYSTEMS; DRUG RELEASE; EUROPEAN MEDICINES AGENCIES; HEAD-AND-NECK CANCER; HUMAN CANCER CELLS; HUMAN COLON; IN-VITRO; INTRACELLULAR ACCUMULATION; PHOTO-TOXICITY; PLGA NANOPARTICLES; POLY(LACTIC-CO-GLYCOLIC ACID); SECOND-GENERATION PHOTOSENSITIZER; TOXIC EFFECT; TUMOURS; WATER SOLUBILITIES;

BIOCOMPATIBILITY; BIODEGRADATION; CELL PROLIFERATION; CYTOTOXICITY; DISEASES; DRUG PRODUCTS; HYDROPHOBICITY; PHOTOSENSITIZERS; TOXICITY;

NANOPARTICLES;

BROXURIDINE; LACTIC ACID; MESOPORPHYRIN; NANOPARTICLE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; TEMOPORFIN;

ARTICLE; CELL DEATH; CELL MEMBRANE; CELL PROLIFERATION; CELL STRAIN HT29; CELL SURVIVAL; COLON TUMOR; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; INTRACELLULAR SPACE; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; PHYSICAL CHEMISTRY; ULTRASTRUCTURE;

BROMODEOXYURIDINE; CELL DEATH; CELL MEMBRANE; CELL PROLIFERATION; CELL SURVIVAL; COLONIC NEOPLASMS; FLOW CYTOMETRY; HT29 CELLS; HUMANS; INTRACELLULAR SPACE; LACTIC ACID; MESOPORPHYRINS; MICROSCOPY, CONFOCAL; NANOPARTICLES; PHYSICOCHEMICAL PHENOMENA; POLYGLYCOLIC ACID; SPHEROIDS, CELLULAR;

EID: 79955832587     PISSN: 09574484     EISSN: 13616528     Source Type: Journal    
DOI: 10.1088/0957-4484/22/24/245102     Document Type: Article

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