Rhabdomyolysis in MDMA intoxication: A rapid and underestimated killer. "clean" Ecstasy, a safe party drug?

Journal of Emergency Medicine

Volumn 42, Issue 6, 2012, Pages 655-658

  Eede, Herve Vanden ^a   Montenij, Leon J ^a   Touw, Daan J ^a   Norris, Elizabeth M ^b  

^a HAGA HOSPITAL   (Netherlands)

^b Princess Elizabeth Hospital   (United Kingdom)

Author keywords

asystole; Ecstasy; hyperkalemia; intoxication; MDMA; methylenedioxymethamphetamine; rhabdomyolysis

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE;

ADULT; ARTICLE; ASYSTOLE; CASE REPORT; CAUSE OF DEATH; COMA; DRUG BLOOD LEVEL; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPERKALEMIA; HYPERTHERMIA; INTOXICATION; MALE; MASS SPECTROMETRY; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; RHABDOMYOLYSIS; SEIZURE;

FATAL OUTCOME; HALLUCINOGENS; HUMANS; HYPERKALEMIA; MALE; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; RHABDOMYOLYSIS; YOUNG ADULT;

EID: 79955827841     PISSN: 07364679     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jemermed.2009.04.057     Document Type: Article

References (15)

1. N.G. Hunfeld, E.M. Westerman, D.J. Boswijk, J.A.M. De Haas, M.J.A.M. Van Putten, and D.J. Touw Quetiapine in overdosage: a clinical and pharmacokinetic analysis of 14 cases Ther Drug Monit 28 2006 185 189 (Pubitemid 44314947)
2. A. Jimmink, K. Caminada, N.G. Hunfeld, and D.J. Touw Clinical toxicology of citalopram after acute intoxication with the sole drug or in combination with other drugs: overview of 26 cases Ther Drug Monit 30 2008 365 371
3. K. Monshouwer, S.van Dorsselar, A. Gorter, J. Verdurmen, and W. Vollenbergh Jeugd en riskant gedrag Kerngegevens uit het peilsationsonderzoek 2003 2004 Trimbos Instituut Utrecht, Netherlands
4. L.H. Ling, C. Marchant, N.A. Buckley, M. Prior, and R.J. Irvine Poisoning with the recreational drug paramethoxyamphetamine ("death") Med J Aust 174 2001 453 455 (Pubitemid 32466069)
5. S.L. Greene, P.I. Dargan, N. O'Connor, A.L. Jones, and M. Kerins Multiple toxicity from 3,4-methylenedioxymethamphetamine ("ecstasy") Am J Emerg Med 21 2003 121 124
6. R. Regenthal, M. Krüger, K. Rudolph, H. Trauer, and R. Preiss Survival after massive "ecstasy" (MDMA) ingestion Intensive Care Med 25 1999 640 641 (Pubitemid 29312605)
7. C. Singarajah, and N.G. Lavies An overdose of ecstasy A role for dantrolene Anaesthesia 47 1992 686 687
8. G.P. Dowling Human deaths and toxic reactions attributed to MDMA and MDEA S.J. Peroutka, The clinical, pharmacological and neurotoxicological effects of the drug MDMA 1990 Kluwer New York 15 32
9. J.A. Henry, K.J. Jeffreys, and S. Dawling Toxicity and deaths from 3,4-methylenedioxymethamphetamine Lancet 340 1992 384 387
10. P. Raviña, J.M. Quiroga, and T. Raviña Hyperkalemia in fatal MDMA ('ecstasy') toxicity Int J Cardiol 93 2004 307 308 (Pubitemid 38229605)
11. L. Strobbe, C.P. de Jaer, E.S. Louwerse, and F.W. Rozendaal Fatal ecstasy intoxication in a 22-year-old man [Dutch] Ned Tijdschr Geneeskd 151 2007 1690 1694 (Pubitemid 47216864)
12. I.H. Fahal, D.F. Sallomi, M. Yaqoob, and G.M. Bell Acute renal failure after ecstasy BMJ 305 1992 29
13. N.T. Campkin, and U.M. Davies Another death from Ecstasy J R Soc Med 85 1992 61
14. S. Refstad Paramethoxyamphetamine (PMA) poisoning; a 'party drug' with lethal effects Acta Anaesthesiol Scand 47 2003 1298 1299 (Pubitemid 37452609)
15. P. Verslaggever Number of children under 16 years admitted in hospital raised with 80% Het Parool May 28, 2008 3