Metastable atom-activated dissociation mass spectrometry of phosphorylated and sulfonated peptides in negative ion mode

Journal of the American Society for Mass Spectrometry

Volumn 22, Issue 6, 2011, Pages 1088-1099

  Cook, Shannon L ^a   Jackson, Glen P ^a  

^a OHIO UNIVERSITY   (United States)

Author keywords

Angiotensin II; Calcitonin; Cholecystokinin; Metastable atom activated dissociation; MS MS; Negative ion mode; Peptide anions; Peptide fragmentation; Phosphorylation; Post translational modification; Sulfonation; Tandem mass spectrometry

Indexed keywords

ANGIOTENSIN II; CALCITONIN; CHOLECYSTOKININ; METASTABLE ATOMS; MS/MS; PEPTIDE ANIONS; PEPTIDE FRAGMENTATION; POST-TRANSLATIONAL MODIFICATIONS; TANDEM MASS SPECTROMETRY;

AMINO ACIDS; ATOMS; CARBON DIOXIDE; HELIUM; MASS SPECTROMETRY; NEGATIVE IONS; PEPTIDES; PHOSPHORYLATION;

DISSOCIATION;

ANGIOTENSIN II; CALCITONIN; CHOLECYSTOKININ; HELIUM; HIRUDIN; LEUCINE ENKEPHALIN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; FRAGMENTATION REACTION; MASS SPECTROMETRY; METASTABLE ATOM ACTIVATED DISSOCIATION MASS SPECTROMETRY; NEGATIVE ION ELECTROSPRAY; PEPTIDE ANALYSIS; PROTEIN CLEAVAGE; PROTEIN ISOLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SENSITIVITY ANALYSIS; SULFONATION; SURFACE CHARGE;

AMINO ACID SEQUENCE; IONS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOPEPTIDES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SULFONIC ACIDS; TANDEM MASS SPECTROMETRY;

EID: 79955823384     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0123-y     Document Type: Article

References (42)

1. BA Garcia J Shabanowitz DF Hunt 2005 Analysis of Protein Phosphorylation by Mass Spectrometry Methods 35 256 264 10.1016/j.ymeth.2004.08.017 1:CAS:528:DC%2BD2MXhslWlsr4%3D (Pubitemid 40255591)
2. E Salih 2005 Phosphoproteomics by Mass Spectrometry and Classical Protein Chemistry Approaches Mass Spectrom. Rev. 24 828 846 10.1002/mas.20042 1:CAS:528:DC%2BD2MXht1WjsbzP (Pubitemid 41641700)
3. YH Yu AJ Hoffhines KL Moore JA Leary 2007 Determination of the Sites of Tyrosine O-Sulfation in Peptides and Proteins Nat. Methods 4 583 588 10.1038/nmeth1056 1:CAS:528:DC%2BD2sXntVCitL0%3D (Pubitemid 47214778)
4. 3 Anal. Chem. 80 9735 9747 10.1021/ac801768s 1:CAS:528:DC%2BD1cXhtlyisbnK
5. M Edelson-Averbukh R Pipkorn WD Lehmann 2006 Phosphate Group-Driven Fragmentation of Multiply Charged Phosphopeptide Anions. Improved Recognition of Peptides Phosphorylated at Serine, Threonine, or Tyrosine by Negative Ion Electrospray Tandem Mass Spectrometry Anal. Chem. 78 1249 1256 10.1021/ac051649v 1:CAS:528:DC%2BD28XjvV2htg%3D%3D (Pubitemid 43271858)
6. K Janek H Wenschuh M Bienert E Krause 2001 Phosphopeptide Analysis by Positive and Negative Ion Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Rapid Commun. Mass Spectrom. 15 1593 1599 10.1002/rcm.417 1:CAS:528:DC%2BD3MXntFWntrY%3D (Pubitemid 32834983)
7. HP Gunawardena JF Emory SA McLuckey 2006 Phosphopeptide Anion Characterization Via Sequential Charge Inversion and Electron-Transfer Dissociation Anal. Chem. 78 3788 3793 10.1021/ac060164j 1:CAS:528: DC%2BD28XjslKgs7w%3D (Pubitemid 43848973)
8. M Salek S Costagliola WD Lehmann 2004 Protein Tyrosine-O-Sulfation Analysis by Exhaustive Product Ion Scanning with Minimum Collision Offset in a NanoESI Q-TOF Tandem Mass Spectrometer Anal. Chem. 76 5136 5142 10.1021/ac0400414 1:CAS:528:DC%2BD2cXmt1Gntrc%3D (Pubitemid 39180344)
9. RL Kelleher RA Zubarev K Bush B Furie BC Furie FW McLafferty CT Walsh 1999 Localization of Labile Posttranslational Modifications by Electron Capture Dissociation: The Case of Gamma-Carboxyglutamic Acid Anal. Chem. 71 4250 4253 10.1021/ac990684x 1:CAS:528:DyaK1MXlt12ksLs%3D (Pubitemid 29466405)
10. LM Mikesh B Ueberheide A Chi JJ Coon JEP Syka J Shabanowitz DF Hunt 2006 The Utility of ETD Mass Spectrometry in Proteomic Analysis Biochem. Biophys. Acta 1764 1811 1822 1:CAS:528:DC%2BD28XhtlaltLzN (Pubitemid 44895029)
11. JEP Syka JJ Coon MJ Schroeder J Shabanowitz DF Hunt 2004 Peptide and Protein Sequence Analysis by Electron Transfer Dissociation Mass Spectrometry Proc. Natl. Acad. Sci. U.S.A. 101 9528 9533 10.1073/pnas.0402700101 1:CAS:528:DC%2BD2cXlvVahs70%3D (Pubitemid 38869270)
12. RA Zubarev NL Kelleher FW McLafferty 1998 Electron Capture Dissociation of Multiply Charged Protein Cations. A Nonergodic Process J. Am. Chem. Soc. 120 3265 3266 10.1021/ja973478k 1:CAS:528:DyaK1cXhslyqt7o%3D
13. A Chi C Huttenhower LY Geer JJ Coon JEP Syka DL Bai J Shabanowitz DJ Burke OG Troyanskaya DF Hunt 2007 Analysis of Phosphorylation Sites on Proteins from Saccharomyces Cerevisiae by Electron Transfer Dissociation (ETD) Mass Spectrometry Proc. Nat. Acad. Sci. U.S.A. 104 2193 2198 10.1073/pnas.0607084104 1:CAS:528:DC%2BD2sXisVWrsLg%3D (Pubitemid 46391374)
14. A Stensballe ON Jensen JV Olsen KF Haselmann RA Zubarev 2000 Electron Capture Dissociation of Singly and Multiply Phosphorylated Peptides Rapid Commun. Mass Spectrom. 14 1793 1800 10.1002/1097-0231(20001015)14:19<1793:: AID-RCM95>3.0.CO;2-Q 1:CAS:528:DC%2BD3cXntVOrtLs%3D
15. K Håkansson HJ Cooper MR Emmett CE Costello AG Marshall CL Nilsson 2001 Electron Capture Dissociation and Infrared Multiphoton Dissociation MS/MS of an N-Glycosylated Tryptic Peptide to Yield Complementary Sequence Information Anal. Chem. 73 4530 4536 10.1021/ac0103470 (Pubitemid 32868256)
16. E Mirgorodskaya P Roepstorff RA Zubarev 1999 Localization of O-Glycosylation Sites in Peptides by Electron Capture Dissociation in a Fourier Transform Mass Spectrometer Anal. Chem. 71 4431 4436 10.1021/ac990578v 1:CAS:528:DyaK1MXlvVSisr8%3D (Pubitemid 29498266)
17. QB Zhang A Frolov N Tang R Hoffmann T van de Goor TO Metz RD Smith 2007 Application of Electron Transfer Dissociation Mass Spectrometry in Analyses of Non-Enzymatically Glycated Peptides Rapid Commun. Mass Spectrom. 21 661 666 10.1002/rcm.2884 1:CAS:528:DC%2BD2sXis12hsrY%3D (Pubitemid 46340309)
18. AJ Creese HJ Cooper 2008 The Effect of Phosphorylation on the Electron Capture Dissociation of Peptide Ions J. Am. Soc. Mass Spectrom. 19 1263 1274 10.1016/j.jasms.2008.05.015 1:CAS:528:DC%2BD1cXhtVyisb7I
19. AW Jones VA Mikhailov J Iniesta HJ Cooper 2010 Electron Capture Dissociation Mass Spectrometry of Tyrosine Nitrated Peptides J. Am. Soc. Mass Spectrom. 21 268 277 10.1016/j.jasms.2009.10.011 1:CAS:528:DC%2BC3cXhtVaktrw%3D
20. CH Sohn CK Chung S Yin P Ramachandran JA Loo JL Beauchamp 2009 Probing the Mechanism of Electron Capture and Electron Transfer Dissociation Using Tags with Variable Electron Affinity J. Am. Chem. Soc. 131 5444 5459 10.1021/ja806534r 1:CAS:528:DC%2BD1MXktVSltr8%3D
21. F Tureček 2010 Electron Predators are Hydrogen Atom Traps. Effects of Aryl Groups on the N-Cα Bond Dissociations of Peptide Radicals J. Mass Spectrom. 45 1280 1290 10.1002/jms.1807
22. H Liu K Håkansson 2006 Electron Capture Dissociation of Tyrosine O-Sulfated Peptides Complexed with Divalent Metal Cations Anal. Chem. 78 7570 7576 10.1021/ac061352c 1:CAS:528:DC%2BD28XpvFKis7s%3D (Pubitemid 44707667)
23. KF Medzihradszky S Guan DA Maltby AL Burlingame 2007 Sulfopeptide Fragmentation in Electron-Capture and Electron-Transfer Dissociation J. Am. Soc. Mass Spectrom. 18 1617 1624 10.1016/j.jasms.2007.06.002 1:CAS:528: DC%2BD2sXps1Glu7Y%3D (Pubitemid 47302322)
24. BA Budnik KF Haselmann RA Zubarev 2001 Electron Detachment Dissociation of Peptide Di-Anions: An Electron-Hole Recombination Phenomenon Chem. Phys. Lett. 342 299 302 10.1016/S0009-2614(01)00501-2 1:CAS:528:DC%2BD3MXltVaitbs%3D (Pubitemid 33628294)
25. HK Kweon K Håkansson 2008 Metal Oxide-Based Enrichment Combined with Gas-Phase Ion-Electron Reactions for Improved Mass Spectrometric Characterization of Protein Phosphorylation J. Proteome Res. 7 749 755 10.1021/pr070386d 1:CAS:528:DC%2BD1cXitlWqug%3D%3D (Pubitemid 351294037)
26. JJ Wolff IJ Amster LL Chi RJ Linhardt 2007 Electron Detachment Dissociation of Glycosaminoglycan Tetrasaccharides J. Am. Soc. Mass Spectrom. 18 234 244 10.1016/j.jasms.2006.09.020 1:CAS:528:DC%2BD2sXht1Wgs70%3D (Pubitemid 46150099)
27. JJ Coon J Shabanowitz DF Hunt JEP Syka 2005 Electron Transfer Dissociation of Peptide Anions J. Am. Soc. Mass Spectrom. 16 880 882 10.1016/j.jasms.2005.01.015 1:CAS:528:DC%2BD2MXktlChtbc%3D (Pubitemid 40725163)
28. M Huzarska I Ugalde DA Kaplan R Hartmer ML Easterling NC Polfer 2010 Negative Electron Transfer Dissociation of Deprotonated Phosphopeptide Anions: Choice of Radical Cation Reagent and Competition between Electron and Proton Transfer Anal. Chem. 82 2873 2878 10.1021/ac9028592 1:CAS:528: DC%2BC3cXivV2mt7c%3D
29. Hersberger, K.E.; Brant, A.; Wang, N.; Håkansson, K.: Proceedings of the 58th ASMS Conference on Mass Spectormetry and Allied Topics. Salt Lake City, UT (May, 2010)
30. Yoo, H.J.; Zhuang, S.; Wang, N.; Håkansson, K.: Proceedings of the 58th ASMS Conference on Mass Spectormetry and Allied Topics. Salt Lake City, UT (May, 2010)
31. SL Cook OL Collin GP Jackson 2009 Metastable Atom-Activated Dissociation Mass Spectrometry: Leucine/Isoleucine Differentiation and Ring Cleavage of Proline Residues J. Mass Spectrom. 44 1211 1223 10.1002/jms.1598 1:CAS:528:DC%2BD1MXhtVCgu7nL
32. SL Cook GP Jackson 2011 Characterization of Tyrosine Nitration and Cysteine Nitrosylation Modifications by Metastable Atom-Activation Dissociation Mass Spectrometry J Am. Soc. Mass Spectrom. 22 221 232 10.1007/s13361-010-0041-4
33. PE Siska 1993 Molecular-Beam Studies of Penning Ionization Rev. Mod. Phys. 65 337 412 10.1103/RevModPhys.65.337 1:CAS:528:DyaK3sXmvVaqsrY%3D
34. VD Berkout 2006 Fragmentation of Protonated Peptide Ions Via Interaction with Metastable Atoms Anal. Chem. 78 3055 3061 10.1021/ac060069a 1:CAS:528:DC%2BD28XjtFWjur8%3D (Pubitemid 43726125)
35. VD Berkout 2009 Fragmentation of Singly Protonated Peptides Via Interaction with Metastable Rare Gas Atoms Anal. Chem. 81 725 731 10.1021/ac802214e 1:CAS:528:DC%2BD1cXhsFantbjF
36. VD Berkout VM Doroshenko 2008 Fragmentation of Phosphorylated and Singly Charged Peptide Ions Via Interaction with Metastable Atoms Int. J. Mass Spectrom. 278 150 157 10.1016/j.ijms.2008.04.019 1:CAS:528:DC%2BD1cXht1Knt7fK
37. AS Misharin OA Silivra F Kjeldsen RA Zubarev 2005 Dissociation of Peptide Ions by Fast Atom Bombardment in a Quadrupole Ion Trap Rapid Commun. Mass Spectrom. 19 2163 2171 10.1002/rcm.2038 1:CAS:528:DC%2BD2MXntVSltLg%3D (Pubitemid 41059874)
38. Cook, S.L.; Jackson, G.P.: Proceedings of the 58th ASMS Conference on Mass Spectormetry and Allied Topics. Salt Lake City, UT (May, 2010)
39. F Kjeldsen OA Silivra IA Ivonin KF Haselmann M Gorshkov RA Zubarev 2005 Cα-C Backbone Fragmentation Dominates in Electron Detachment Dissociation of Gas-Phase Polypeptide Polyanions Chem. Eur. J. 11 1803 1812 10.1002/chem.200400806 1:CAS:528:DC%2BD2MXisVWjurY%3D (Pubitemid 40379844)
40. HJ Cooper RR Hudgins K Håkansson AG Marshall 2002 Characterization of Amino Acid Side Chain Losses in Electron Capture Dissociation J. Am. Soc. Mass Spectrom. 13 241 249 10.1016/S1044-0305(01)00357-9 1:CAS:528: DC%2BD38XhsleqsL4%3D (Pubitemid 34552604)
41. MM Savitski ML Nielsen RA Zubarev 2007 Side-Chain Losses in Electron Capture Dissociation to Improve Peptide Identification Anal. Chem. 79 2296 2302 10.1021/ac0619332 1:CAS:528:DC%2BD2sXht1WqsbY%3D (Pubitemid 46449008)
42. F Kjeldsen KF Haselmann ES Sorensen RA Zubarev 2003 Distinguishing of Ile/Leu Amino Acid Residues in the PP3 Protein by (Hot) Electron Capture Dissociation in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Anal. Chem. 75 1267 1274 10.1021/ac020422m 1:CAS:528:DC%2BD3sXhs1agug%3D%3D (Pubitemid 36397157)