Mechanisms of the apoptosis induced by CD176 antibody in human leukemic cells

International Journal of Oncology

Volumn 38, Issue 6, 2011, Pages 1565-1573

  Yi, Bin ^a,b   Zhang, Min ^a,b   Schwartz Albiez, Reinhard ^c   Cao, Yi ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Apoptosis; CD176; Leukemia; Signaling pathway; Thomsen Friedenreich antigen

Indexed keywords

CARBOHYDRATE; CASPASE 3; CD176 ANTIBODY; CD45 ANTIGEN; CELL ANTIBODY; DEATH RECEPTOR 4; FAS ANTIGEN; LEUKOSIALIN; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL SURFACE; CHROMATIN IMMUNOPRECIPITATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG TARGETING; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANTIBODIES; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; APOPTOSIS; CELL LINE, TUMOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; HL-60 CELLS; HUMANS; K562 CELLS; LEUKEMIA; MODELS, BIOLOGICAL; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; U937 CELLS;

EID: 79955822124     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.992     Document Type: Article

References (36)

1. Clausen H and Hakomori S: ABH and related histo-blood group antigens; immunochemical differences in carrier isotypes and their distribution. Vox Sang 56: 1-20, 1989. (Pubitemid 19023824)
2. Kim Z and Uhlenbruck G: Untersuchungen über T-Antigen und T-Agglutinin. Z Immunol Forsch 130: 88-99, 1966.
3. Cao Y, Karsten U and Schwartz-Albiez R: Expression of Thomsen-Friedenreich-related carbohydrate antigens on human leukemia cells. In: Leucocyte Typing VII. Mason D, et al (eds). Oxford University Press, Oxford, pp204-205, 2002.
4. Cao Y, Stosiek P, Springer GF and Karsten U: Thomsen-Friedenreich-related carbohydrate antigens in normal adult human tissues: a systematic and comparative study. Histochem cell Biol 106: 197-207, 1996. (Pubitemid 26281400)
5. Springer GF: T and Tn, general carcinoma autoantigens. Science 224: 1198-1206, 1984.
6. Springer GF: Immunoreactive T and Tn epitopes in cancer diagnosis, prognsis and immunotherapy. J Mol Med 75: 594-602, 1997.
7. + cells. Blood 83: 84-91, 1994.
8. Aller CT, Kucuk O, Springer GF and Gilman-Sachs A: Flow cytometric analysis of T and Tn epitopes on chronic lymphocytic leukemia cells. Am J Hematol 52: 29-38, 1996. (Pubitemid 26140039)
9. Inoue M, Nakada H, Tanaka N and Yamashina I: Tn antigen is expressed on leukosialin from T-lymphoid cells. Cancer Res 54: 85-88, 1994. (Pubitemid 24042092)
10. Kaspers GJ, Veerman AJ, Van Wering ER, et al: Prognostic significance of peanut agglutinin binding in childhood acute lymphoblastic leukemia. Leukemia 10: 675-681, 1996. (Pubitemid 26144449)
11. Veerman AJ, Hogeman PH, Huismans DR, Van Zantwijk CH and Bezemer PD: Peanut agglutinin, a marker for T-cell acute lymphoblastic leukemia with a good prognosis. Cancer Res 45: 1890-1893, 1985.
12. Cao Y, Merling A, Karsten U, et al: Expression of CD175 (Tn), CD175s (sialosyl-Tn) and CD176 (Thomsen-Friedenreich antigen) on malignant human hematopoietic cells. Int J Cancer 123: 89-99, 2008. (Pubitemid 351705196)
13. Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462, 1995.
14. Fesik SW: Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer 5: 876-885, 2005.
15. Ravindranath NM, Nishimoto K, Chu K and Shuler C: Cell-surface expression of complement restriction factors and sialyl Lewis antigens in oral carcinoma: relevance to chemo-immunotherapy. Anticancer Res 20: 21-26, 2000. (Pubitemid 30189729)
16. Peter ME, Hellbardt S, Schwartz-Albibez R, et al: Cell surface sialylation plays a role in modulating sensitivity towards APO-1-mediated apoptotic cell death. Cell Death Differ 2: 163-171, 1995.
17. Park WS, Chae JS, Jung KC, Choi WJ, Kook MC and Bae Y: Production and the characterization of monoclonal antibody against CD43, K06. Tissue Antigens 63: 46-53, 2004. (Pubitemid 38130442)
18. Blaylock MG, Sexton DW and Walsh GM: Ligation of CD45 and the isoforms CD45RA and CD45RB accelerates the rate of constitutive apoptosis in human eosinophils. J Allergy Clin Immunol 104: 1244-1250, 1999. (Pubitemid 30004987)
19. Karsten U, Butschak G, Cao Y, Goletz S and Hanisch FG: A new monoclonal antibody (A78-G/A7) to the Thomsen-Friedenreich pan-tumor antigen. Hybridoma 14: 37-44, 1995.
20. Lin WM, Karsten U, Goletz S, Cheng RC and Cao Y: Expression of CD176 (Thomsen-Friedenreich antigen) on lung, breast and liver cancer-initiating cells. Int J Exp Pathol 92: 97-105, 2011.
21. Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C (T)) method. Methods 25: 402-408, 2001. (Pubitemid 34164012)
22. Chang HR: Trastuzumab-based neoadjuvant therapy in patients with HER2-positive breast cancer. Cancer 116: 2856-2867, 2010.
23. Brändlein S, Pohle T, Ruoff N, Wozniak K, Müller-Hermelink HK and Vollmers HP: Natural IgM antibodies and immunosurveillance mechanisms against epithelial cancer cells in humans. Cancer Res 63: 7995-8005, 2003.
24. Axelsson B, Hammarstrom S, Finne J and Perlmann P: The large sialoglycoprotein of human lymphocytes. II. Biochemical features. Eur J Immunol 15: 427-433, 1985. (Pubitemid 15071571)
25. Cermak L, Simova S, Pintzas A, Horejsi V and Andera L: Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules. J Biol Chem 277: 7955-7961, 2002. (Pubitemid 34968246)
26. Nguyen JT, Evans DP, Galvan M, Pace KE, Leitenberg D, Bui TN and Baum LG: CD45 modulates galectin-1-induced T cell death: regulation by expression of core 2 O-glycans. J Immunol 167: 5697-5707, 2001. (Pubitemid 33062760)
27. Hernandez JD, Nguyen JT, He J, et al: Galectin-1 binds different CD43 glycoforms to cluster CD43 and regulate T cell death. J Immunol 177: 5328-5336, 2006. (Pubitemid 44527605)
28. Ma BY, Yoshida K, Baba M, et al: The lectin Jacalin induces human B-lymphocyte apoptosis through glycosylation-dependent interaction with CD45. Immunology 127: 447-488, 2009.
29. Marsters SA, Sheridan JP, Pitti RM, et al: A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr Biol 7: 1003-1006, 1997. (Pubitemid 28017080)
30. Varambally S, Bar-Dayan Y, Bayry J, et al: Natural human polyreactive IgM induce apoptosis of lymphoid cell lines and human peripheral blood mononuclear cells. Int Immunol 16: 517-524, 2004. (Pubitemid 38313160)
31. Kim HJ, Park HJ, Park WS and Bae Y: CD43 cross-linking increases the Fas-induced apoptosis through induction of Fas aggregation in Jurkat T-cells. Exp Mol Med 38: 357-363, 2006. (Pubitemid 44390513)
32. Kovacs-Solyom F, Blasko A, Fajka-Boja R, et al: Mechanism of tumor cell-induced T-cell apoptosis mediated by galectin-1. Immunol Lett 127: 108-118, 2010.
33. Algeciras-Schimnich A, Shen L, Barnhart BC, Murmann AE, Burkhardt JK and Peter ME: Molecular ordering of the initial signaling events of CD95. Mol Cell Biol 22: 207-220, 2002. (Pubitemid 33144269)
34. Brändlein S, Rauschert N, Rasche L, et al: The human IgM antibody SAM-6 induces tumor-specific apoptosis with oxidized low-density lipoprotein. Mol Cancer Ther 6: 326-333, 2007. (Pubitemid 46206697)
35. Rauschert N, Brändlein S, Holzinger E, Hensel F, Müller-Hermelink HK and Vollmers HP: A new tumor-specific variant of GRP78 as target for antibody-based therapy. Lab Invest 88: 375-386, 2008. (Pubitemid 351432774)
36. Wagner, KW, Punnoose EA, Januario T, et al: Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Nat Med 13: 1070-1077, 2007. (Pubitemid 47517508)