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Volumn 51, Issue 6, 2011, Pages 842-856
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Population pharmacokinetics of eltrombopag in healthy subjects and patients with chronic idiopathic thrombocytopenic purpura
a,c
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Author keywords
clinical; Clinical pharmacology; clinical trials; hematology; pharmacokinetics and drug metabolism; research
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Indexed keywords
CORTICOSTEROID;
CREATININE;
ELTROMBOPAG;
ADULT;
AFRICAN AMERICAN;
AGE;
AREA UNDER THE CURVE;
ARTICLE;
ASIAN;
BODY MASS;
BODY WEIGHT;
CAUCASIAN;
COMPARTMENT MODEL;
CONTROLLED STUDY;
CORTICOSTEROID THERAPY;
CREATININE CLEARANCE;
DOSE RESPONSE;
DRUG ABSORPTION;
DRUG BLOOD LEVEL;
DRUG CAPSULE;
DRUG CLEARANCE;
DRUG DISTRIBUTION;
DRUG DOSE ESCALATION;
DRUG EXPOSURE;
FEMALE;
HUMAN;
IDIOPATHIC THROMBOCYTOPENIC PURPURA;
JAPANESE;
MAJOR CLINICAL STUDY;
MALE;
MAXIMUM PLASMA CONCENTRATION;
NORMAL HUMAN;
POPULATION RESEARCH;
RACE;
REPEATED DRUG DOSE;
SEX DIFFERENCE;
SINGLE DRUG DOSE;
STEADY STATE;
TABLET;
WEIGHT GAIN;
ADOLESCENT;
ADULT;
AGED;
AGED, 80 AND OVER;
ASIAN CONTINENTAL ANCESTRY GROUP;
BENZOIC ACIDS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
EUROPEAN CONTINENTAL ANCESTRY GROUP;
FEMALE;
HUMANS;
HYDRAZINES;
MALE;
MIDDLE AGED;
MODELS, STATISTICAL;
PURPURA, THROMBOCYTOPENIC, IDIOPATHIC;
PYRAZOLES;
RECEPTORS, THROMBOPOIETIN;
SEX CHARACTERISTICS;
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EID: 79955820299
PISSN: 00912700
EISSN: 15524604
Source Type: Journal
DOI: 10.1177/0091270010375427 Document Type: Article |
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Times cited : (72)
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References (11)
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