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Volumn 25, Issue 5, 2011, Pages 874-877

The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: A study in 39 cases of MDS or AML

Author keywords

[No Author keywords available]

Indexed keywords

K RAS PROTEIN; NEUROFIBROMIN; TRANSCRIPTION FACTOR RUNX1;

EID: 79955814184     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.5     Document Type: Letter
Times cited : (40)

References (8)
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    • High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities
    • Gröschel S, Lugthart S, Schlenk RF, Valk PJ, Eiwen K, Goudswaard C et al. High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities. J Clin Oncol 2010; 28: 2101-2107.
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  • 4
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    • Refinement of cytogenetic classification in acute myeloid leukemia: Determination of prognostic significance of rare recurring chromosomal abnormalities amongst 5,876 younger adult patients treated in the UK Medical Research Council trials
    • Grimwade D, Hills R, Moorman AV, Walker H, Chatters S, Goldstone A et al. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities amongst 5,876 younger adult patients treated in the UK Medical Research Council trials. Blood 2010; 116: 354-365.
    • (2010) Blood , vol.116 , pp. 354-365
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  • 5
    • 77956247735 scopus 로고    scopus 로고
    • Clinical, molecular, and prognostic significance of WHO type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and various other 3q abnormalities in acute myeloid leukemia
    • Lugthart S, Gröschel S, Beverloo HB, Kayser S, Valk PJ, Van Zelderen-Bhola SL et al. Clinical, molecular, and prognostic significance of WHO type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and various other 3q abnormalities in acute myeloid leukemia. J Clin Oncol 2010; 20: 3890-3898.
    • (2010) J Clin Oncol , vol.20 , pp. 3890-3898
    • Lugthart, S.1    Gröschel, S.2    Beverloo, H.B.3    Kayser, S.4    Valk, P.J.5    Van Zelderen-Bhola, S.L.6
  • 6
    • 33646575624 scopus 로고    scopus 로고
    • Implications of NRAS mutations in AML: A study of 2502 patients
    • DOI 10.1182/blood-2005-08-3522
    • Bacher U, Haferlach T, Schoch C, Kern W, Schnittger S. Implications of NRAS mutations in AML: a study of 2502 patients. Blood 2006; 107: 3847-3853. (Pubitemid 43726786)
    • (2006) Blood , vol.107 , Issue.10 , pp. 3847-3853
    • Bacher, U.1    Haferlach, T.2    Schoch, C.3    Kern, W.4    Schnittger, S.5
  • 7
    • 77952420655 scopus 로고    scopus 로고
    • AML with CBFB-MYH11 rearrangement demonstrate RAS pathway alterations in 92% of all cases including a high frequency of NF1 deletions
    • Haferlach C, Dicker F, Kohlmann A, Schindela S, Weiss T, Kern W et al. AML with CBFB-MYH11 rearrangement demonstrate RAS pathway alterations in 92% of all cases including a high frequency of NF1 deletions. Leukemia 2010; 24: 1065-1069.
    • (2010) Leukemia , vol.24 , pp. 1065-1069
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    • Weisser M, Haferlach C, Haferlach T, Schnittger S. Advanced age and high initial WBC influence the outcome of inv(3)(q21q26)/ t(3;3)(q21;q26) positive AML. Leuk Lymphoma 2007; 48: 2145-2151. (Pubitemid 350107691)
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.