Direct inoculation of mycobacterium avium subspecies paratuberculosis into ileocecal peyer's patches results in colonization of the intestine in a calf model

Veterinary Pathology

Volumn 48, Issue 3, 2011, Pages 584-592

  Plattner, Brandon L ^a   Chiang, Y W ^b   Roth, J A ^a   Platt, R ^a   Huffman, E ^a   Zylstra, J ^b   Hostetter, J M ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b ZOETIS   (United States)

Author keywords

bovine; immunology; intestinal; mycobacteria; paratuberculosis

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 4;

ANIMAL; ARTICLE; CATTLE; CATTLE DISEASE; GENETICS; HUMORAL IMMUNITY; IMMUNOLOGY; INTESTINE; MALE; METABOLISM; MICROBIOLOGY; MYCOBACTERIUM PARATUBERCULOSIS; PARATUBERCULOSIS; PATHOLOGY; PEYER PATCH; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; CATTLE; CATTLE DISEASES; IMMUNITY, HUMORAL; INTERFERON-GAMMA; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-4; INTESTINES; MALE; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS; PARATUBERCULOSIS; PEYER'S PATCHES; T-LYMPHOCYTE SUBSETS;

ANIMALIA; BACILLI (CLASS); BACTERIA (MICROORGANISMS); BOVINAE; CORYNEBACTERINEAE; MYCOBACTERIUM; MYCOBACTERIUM AVIUM; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS;

EID: 79955808802     PISSN: 03009858     EISSN: 15442217     Source Type: Journal    
DOI: 10.1177/0300985810383874     Document Type: Article

References (26)

1. Allen AJ,Park KT,Barrington GM, et al. Development of a bovine ileal cannulation model to study the immune response and mechanisms of pathogenesis of paratuberculosis. Clin Vaccine Immunol. 2009;16: 453-463.
2. Begg DJ,Whittington RJ. Experimental animal infection models for Johne's disease, an infectious enteropathy caused by Mycobacterium avium subsp. paratuberculosis. Vet J. 2008;176:: 129-145.
3. Coussens PM. Model for immune responses to Mycobacterium avium subspecies paratuberculosis in cattle. Infect Immun. 2004;72: 3089-3096.
4. Coussens PM,Verman N,Coussens MA, et al. Cytokine gene expression in peripheral blood mononuclear cells and tissues of cattle infected with Mycobacterium avium subsp. paratuberculosis: evidence for an inherent proinflammatory gene expression pattern. Infect Immun. 2004;72: 1409-1422.
5. Gor DO,Rose NR,Greenspan NS. TH1-TH2: a procrustean paradigm. Nat Immunol. 2003;4: 503-505.
6. Hines ME II,Stabel JR,Sweeney RW, et al. Experimental challenge models for Johne's disease: a review and proposed international guidelines. Vet Microbiol. 2007;122: 197-222.
7. Khare S,Nunes JS,Figueiredo JF, et al. Early phase morphological lesions and transcriptional responses of bovine ileum infected with Mycobacterium avium subsp. paratuberculosis. Vet Pathol. 2009;46: 717-728.
8. Koets A,Hoek A,Langelaar M, et al. Mycobacterial 70 kD heat-shock protein is an effective subunit vaccine against bovine paratuberculosis. Vaccine. 2006;24: 2550-2559.
9. Koo HC,Park YH,Hamilton MJ, et al. Analysis of the immune response to Mycobacterium avium subsp. paratuberculosis in experimentally infected calves. Infect Immun. 2004;72: 6870-6883.
10. Lee H,Stabel JR,Kehrli ME. Cytokine gene expression in ileal tissues of cattle infected with Mycobacterium paratuberculosis. Vet Immunol Immunopathol. 2001;82: 73-85.
11. Nielsen SS. Transitions in diagnostic tests used for detection of Mycobacterium avium subsp. paratuberculosis infections in cattle. Vet Microbiol. 2008;132: 274-282.
12. Nielsen SS,Toft N. Ante mortem diagnosis of paratuberculosis: a review of accuracies of ELISA, interferon-gamma assay and faecal culture techniques. Vet Microbiol. 2008;129: 217-235.
13. Platt R,Roth JA,Royer RL, et al. Monitoring responses by use of five-color flow cytometry in subsets of peripheral T cells obtained from cattle inoculated with a killed Mycobacterium avium subsp paratuberculosis vaccine. Am J Vet Res. 2006;67:: 2050-2058.
14. Platt R,Thoen CO,Stalberger RJ, et al. Evaluation of the cell-mediated immune response to reduced doses of Mycobacterium avium ssp. Paratuberculosis vaccine in cattle. Vet Immunol Immunopathol. 2010;136:122-126.
15. Pott J,Basler T,Duerr CU, et al. Internalization-dependent recognition of Mycobacterium avium ssp. paratuberculosis by intestinal epithelial cells. Cell Microbiol. 2009;11: 1802-1815.
16. Rosseels V,Marche S,Roupie V, et al. Members of the 30- to 32-kilodalton mycolyl transferase family (Ag85) from culture filtrate of Mycobacterium avium subsp. paratuberculosis are immunodominant Th1-type antigens recognized early upon infection in mice and cattle. Infect Immun. 2006;74: 202-212.
17. Seth M,Lamont EA,Janagama HK, et al. Biomarker discovery in subclinical mycobacterial infections of cattle. PLoS One. 2009;4: e5478.
18. Stabel JR. Host responses to Mycobacterium avium subsp. paratuberculosis: a complex arsenal. Anim Health Res Rev. 2006;7: 61-70.
19. Stabel JR,Palmer MV,Harris B, et al. Pathogenesis of Mycobacterium avium subsp. paratuberculosis in neonatal calves after oral or intraperitoneal experimental infection. Vet Microbiol. 2009;136:: 306-313.
20. Stabel JR,Palmer MV,Whitlock RH. Immune responses after oral inoculation of weanling bison or beef calves with a bison or cattle isolate of Mycobacterium avium subsp. paratuberculosis. J Wildl Dis. 2003;39: 545-555.
21. Stabel JR,Whitlock RH. An evaluation of a modified interferon-gamma assay for the detection of paratuberculosis in dairy herds. Vet Immunol Immunopathol. 2001;79: 69-81.
22. Sweeney RW,Uzonna J,Whitlock RH, et al. Tissue predilection sites and effect of dose on Mycobacterium avium subs. paratuberculosis organism recovery in a short-term bovine experimental oral infection model. Res Vet Sci. 2006;80: 253-259.
23. Uzonna JE,Chilton P,Whitlock RH, et al. Efficacy of commercial and field-strain Mycobacterium paratuberculosis vaccinations with recombinant IL-12 in a bovine experimental infection model. Vaccine. 2003;21: 3101-3109.
24. Waters WR,Miller JM,Palmer MV, et al. Early induction of humoral and cellular immune responses during experimental Mycobacterium avium subsp. paratuberculosis infection of calves. Infect Immun. 2003;71: 5130-5138.
25. Weiss DJ,Evanson OA,Souza CD. Mucosal immune response in cattle with subclinical Johne's disease. Vet Pathol. 2006;43: 127-135.
26. Wu CW,Livesey M,Schmoller SK, et al. Invasion and persistence of Mycobacterium avium subsp. paratuberculosis during early stages of Johne's disease in calves. Infect Immun. 2007;75:: 2110-2119.