-
1
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer disease and Down syndrome
-
DOI 10.1073/pnas.82.12.4245
-
Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci USA 1985;82:4245-4249. (Pubitemid 15053619)
-
(1985)
Proceedings of the National Academy of Sciences of the United States of America
, vol.82
, Issue.12
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
-
2
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe DJ. The molecular pathology of Alzheimer's disease. Neuron 1991;6:487-498.
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
3
-
-
55949117032
-
Frequent amyloid deposition without significant cognitive impairment among the elderly
-
Aizenstein HJ, Nebes RD, Saxton JA, Price JC, Mathis CA, Tsopelas ND, Ziolko SK, James JA, Snitz BE, Houck PR, et al. Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol 2008; 65:1509-1517.
-
(2008)
Arch Neurol
, vol.65
, pp. 1509-1517
-
-
Aizenstein, H.J.1
Nebes, R.D.2
Saxton, J.A.3
Price, J.C.4
Mathis, C.A.5
Tsopelas, N.D.6
Ziolko, S.K.7
James, J.A.8
Snitz, B.E.9
Houck, P.R.10
-
4
-
-
0029939891
-
A comparison of β-amyloid deposition in the medial temporal lobe in sporadic Alzheimer's disease, Down's syndrome and normal elderly brains
-
DOI 10.1006/neur.1996.0005
-
Armstrong RA, Cairns NJ, Myers D, Smith CU, Lantos PL, Rossor MN. A comparison of beta-amyloid deposition in the medial temporal lobe in sporadic Alzheimer's disease, Down's syndrome and normal elderly brains. Neurodegeneration 1996;5:35-41. (Pubitemid 26132265)
-
(1996)
Neurodegeneration
, vol.5
, Issue.1
, pp. 35-41
-
-
Armstrong, R.A.1
Cairns, N.J.2
Myers, D.3
Smith, C.U.M.4
Lantos, P.L.5
Rossor, M.N.6
-
5
-
-
33646035489
-
Mild cognitive impairment
-
Gauthier S, Reisberg B, Zaudig M, Petersen RC, Ritchie K, Broich K, Belleville S, Brodaty H, Bennett D, Chertkow H, et al. Mild cognitive impairment. Lancet 2006;367:1262-1270.
-
(2006)
Lancet
, vol.367
, pp. 1262-1270
-
-
Gauthier, S.1
Reisberg, B.2
Zaudig, M.3
Petersen, R.C.4
Ritchie, K.5
Broich, K.6
Belleville, S.7
Brodaty, H.8
Bennett, D.9
Chertkow, H.10
-
6
-
-
0032988610
-
Mild cognitive impairment: Clinical characterization and outcome
-
Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: Clinical characteriza-tion and outcome. Arch Neurol 1999;56:303-308. (Pubitemid 29120227)
-
(1999)
Archives of Neurology
, vol.56
, Issue.3
, pp. 303-308
-
-
Petersen, R.C.1
Smith, G.E.2
Waring, S.C.3
Ivnik, R.J.4
Tangalos, E.G.5
Kokmen, E.6
-
7
-
-
29844455077
-
A comparison of immunohistochemical and silver staining methods for the detection of diffuse plaques in the aged canine brain
-
DOI 10.1016/j.neurobiolaging.2005.02.017, PII S0197458005001661
-
Czasch S, Paul S, Baumgartner W. A comparison of immunohistochemical and silver staining methods for the detection of diffuse plaques in the aged canine brain. Neurobiol Aging 2006;27:293-305. (Pubitemid 43038554)
-
(2006)
Neurobiology of Aging
, vol.27
, Issue.2
, pp. 293-305
-
-
Czasch, S.1
Paul, S.2
Baumgartner, W.3
-
8
-
-
0025885348
-
Modified bielschowsky and immunohistochem-ical studies on senile plaques in aged dogs
-
Shimada A, Kuwamura M, Umemura T, Takada K, Ohama E, Itakura C. Modified bielschowsky and immunohistochem-ical studies on senile plaques in aged dogs. Neurosci Lett 1991;129:25-28.
-
(1991)
Neurosci Lett
, vol.129
, pp. 25-28
-
-
Shimada, A.1
Kuwamura, M.2
Umemura, T.3
Takada, K.4
Ohama, E.5
Itakura, C.6
-
9
-
-
0026287550
-
Pathological studies on cerebral amyloid angiopathy, senile plaques and amyloid deposition in visceral organs in aged dogs
-
Uchida K, Nakayama H, Goto N. Pathological studies on cerebral amyloid angiopathy, senile plaques and amyloid deposition in visceral organs in aged dogs. J Vet Med Sci 1991;53:1037-1042.
-
(1991)
J Vet Med Sci
, vol.53
, pp. 1037-1042
-
-
Uchida, K.1
Nakayama, H.2
Goto, N.3
-
10
-
-
21644482235
-
Immunohistochemical investigation of amyloid β-protein (Aβ) in the brain of aged cats
-
Brellou G, Vlemmas I, Lekkas S, Papaioannou N. Immuno-histochemical investigation of amyloid beta-protein (abeta) in the brain of aged cats. Histol Histopathol 2005;20:725-731. (Pubitemid 40932590)
-
(2005)
Histology and Histopathology
, vol.20
, Issue.3
, pp. 725-731
-
-
Brellou, G.1
Vlemmas, I.2
Lekkas, S.3
Papaioannou, N.4
-
11
-
-
0029923152
-
Senile plaques in very aged cats
-
DOI 10.1007/s004010050448
-
Nakamura S, Nakayama H, Kiatipattanasakul W, Uetsuka K, Uchida K, Goto N. Senile plaques in very aged cats. Acta Neuropathol 1996;91:437-439. (Pubitemid 26088982)
-
(1996)
Acta Neuropathologica
, vol.91
, Issue.4
, pp. 437-439
-
-
Nakamura, S.-I.1
Nakayama, H.2
Kiatipattanasakul, W.3
Uetsuka, K.4
Uchida, K.5
Goto, N.6
-
12
-
-
0029381717
-
Histopathological studies on senile plaques and cerebral amyloid angiopathy in aged cynomolgus monkeys
-
Nakamura S, Nakayama H, Goto N, Ono-Ochikubo F, Sakakibara I, Yoshikawa Y. Histopathological studies on senile plaques and cerebral amyloid angiopathy in aged cynomolgus monkeys. Exp Anim 1995;43:711-718.
-
(1995)
Exp Anim
, vol.43
, pp. 711-718
-
-
Nakamura, S.1
Nakayama, H.2
Goto, N.3
Ono-Ochikubo, F.4
Sakakibara, I.5
Yoshikawa, Y.6
-
13
-
-
0022359443
-
Senile plaques in cortex of aged normal monkeys
-
DOI 10.1016/0006-8993(85)91298-3
-
Struble RG, Price DL Jr, Cork LC, Price DL. Senile plaques in cortex of aged normal monkeys. Brain Res 1985;361:267-275. (Pubitemid 16185363)
-
(1985)
Brain Research
, vol.361
, Issue.1-2
, pp. 267-275
-
-
Struble, R.G.1
Price Jr., D.L.2
Cork, L.C.3
Price, D.L.4
-
14
-
-
0025061535
-
Amyloid in the brains of aged squirrel monkeys
-
DOI 10.1007/BF00307691
-
Walker LC, Masters C, Beyreuther K, Price DL. Amyloid in the brains of aged squirrel monkeys. Acta Neuropathol 1990;80:381-387. (Pubitemid 20255761)
-
(1990)
Acta Neuropathologica
, vol.80
, Issue.4
, pp. 381-387
-
-
Walker, L.C.1
Masters, C.2
Beyreuther, K.3
Price, D.L.4
-
15
-
-
0015733914
-
Neuritic (senile) plaques and filamentous changes in aged rhesus monkeys
-
Wisniewski HM, Ghetti B, Terry RD. Neuritic (senile) plaques and filamentous changes in aged rhesus monkeys. J Neuropathol Exp Neurol 1973;32:566-584.
-
(1973)
J Neuropathol Exp Neurol
, vol.32
, pp. 566-584
-
-
Wisniewski, H.M.1
Ghetti, B.2
Terry, R.D.3
-
16
-
-
0023707215
-
Neurofibrillary tangles and senile plaques in aged bears
-
Cork LC, Powers RE, Selkoe DJ, Davies P, Geyer JJ, Price DL. Neurofibrillary tangles and senile plaques in aged bears. J Neuropathol Exp Neurol 1988;47:629-641.
-
(1988)
J Neuropathol Exp Neurol
, vol.47
, pp. 629-641
-
-
Cork, L.C.1
Powers, R.E.2
Selkoe, D.J.3
Davies, P.4
Geyer, J.J.5
Price, D.L.6
-
17
-
-
0029339834
-
Senile plaques and other senile changes in the brain of an aged american black bear
-
Uchida K, Yoshino T, Yamaguchi R, Tateyama S, Kimoto Y, Nakayama H, Goto N. Senile plaques and other senile changes in the brain of an aged american black bear. Vet Pathol 1995;32:412-414.
-
(1995)
Vet Pathol
, vol.32
, pp. 412-414
-
-
Uchida, K.1
Yoshino, T.2
Yamaguchi, R.3
Tateyama, S.4
Kimoto, Y.5
Nakayama, H.6
Goto, N.7
-
18
-
-
0029938433
-
Aβ-Associated cerebral angiopathy and senile plaques with neurofibrillary tangles and cerebral hemorrhage in an aged wolverine (Gulo gulo)
-
DOI 10.1016/0197-4580(95)02069-1
-
Roertgen KE, Parisi JE, Clark HB, Barnes DL, O'Brien TD, Johnson KH. A beta-associated cerebral angiopathy and senile plaques with neurofibrillary tangles and cerebral hemorrhage in an aged wolverine (gulo gulo). Neurobiol Aging 1996;17: 243-247. (Pubitemid 26167635)
-
(1996)
Neurobiology of Aging
, vol.17
, Issue.2
, pp. 243-247
-
-
Roertgen, K.E.1
Parisi, J.E.2
Clark, H.B.3
Barnes, D.L.4
O'Brien, T.D.5
Johnson, K.H.6
-
19
-
-
0029120313
-
Senile plaques in an aged two-humped (bactrian) camel (camelus bactrianus)
-
Nakamura S, Nakayama H, Uetsuka K, Sasaki N, Uchida K, Goto N. Senile plaques in an aged two-humped (bactrian) camel (camelus bactrianus). Acta Neuropathol 1995;90:415-418.
-
(1995)
Acta Neuropathol
, vol.90
, pp. 415-418
-
-
Nakamura, S.1
Nakayama, H.2
Uetsuka, K.3
Sasaki, N.4
Uchida, K.5
Goto, N.6
-
20
-
-
0032782814
-
Cerebral amyloid angiopathy in an aged great spotted woodpecker (Picoides major)
-
DOI 10.1016/S0197-4580(99)00004-4, PII S0197458099000044
-
Nakayama H, Katayama K, Ikawa A, Miyawaki K, Shinozuka J, Uetsuka K, Nakamura S, Kimura N, Yoshikawa Y, Doi K. Cerebral amyloid angiopathy in an aged great spotted wood-pecker (picoides major). Neurobiol Aging 1999;20:53-56. (Pubitemid 29352363)
-
(1999)
Neurobiology of Aging
, vol.20
, Issue.1
, pp. 53-56
-
-
Nakayama, H.1
Katayama, K.-I.2
Ikawa, A.3
Miyawaki, K.4
Shinozuka, J.5
Uetsuka, K.6
Nakamura, S.-I.7
Kimura, N.8
Yoshikawa, Y.9
Doi, K.10
-
21
-
-
0035093896
-
Immunohistochemical investigation of the brain of aged dogs. I. Detection of neurofibrillary tangles and of 4-hydroxynonenal protein, an oxidative damage product, in senile plaques
-
Papaioannou N, Tooten PCJ, van Ederen AM, Bohl JRE, Rofina J, Tsangaris T, Gruys E. Immunohistochemical investigation of the brain of aged dogs. I. Detection of neurofibrillary tangles and and of 4-hydroxynonenal protein, an oxidative damage product, in senile plaques. Amyloid 2001;8:11-21. (Pubitemid 32210176)
-
(2001)
Amyloid
, vol.8
, Issue.1
, pp. 11-21
-
-
Papaioannou, N.1
Tooten, P.C.J.2
Van Ederen, A.M.3
Bohl, J.R.E.4
Rofina, J.5
Tsangaris, T.6
Gruys, E.7
-
22
-
-
0042703651
-
Canine counterpart of senile dementia of the Alzheimer type: Amyloid plaques near capillaries but lack of spatial relationship with activated microglia and macrophages
-
Rofina J, van Andel I, van Ederen AM, Papaioannou N, Yamaguchi H, Gruys E. Canine counterpart of senile dementia of the Alzheimer type: amyloid plaques near capillaries but lack of spatial relationship with activated microglia and macrophages. Amyloid 2003;10:86-96. (Pubitemid 36936539)
-
(2003)
Amyloid
, vol.10
, Issue.2
, pp. 86-96
-
-
Rofina, J.1
Van Andel, I.2
Van Ederen, A.M.3
Papaioannou, N.4
Yamaguchi, H.5
Gruys, E.6
-
23
-
-
4544285567
-
Histochemical accumulation of oxidative damage products is associated with Alzheimer-like pathology in the canine
-
DOI 10.1080/13506120412331285779
-
Rofina JE, Singh K, Skoumalova-Vesela A, van Ederen AM, van Asten AJAM, Wilhelm J, Gruys E. Histochemical accumulation of oxidative damage products is associated with Alzheimer-like pathology in the canine. Amyloid 2004;11:90-100. (Pubitemid 39222405)
-
(2004)
Amyloid
, vol.11
, Issue.2
, pp. 90-100
-
-
Rofina, J.E.1
Singh, K.2
Skoumalova-Vesela, A.3
Van Ederen, A.M.4
Van Asten, A.J.A.M.5
Wilhelm, J.6
Gruys, E.7
-
24
-
-
0034837627
-
Transgenic mouse models of Alzheimer's disease
-
DOI 10.1016/S0031-9384(01)00524-8, PII S0031938401005248
-
Janus C, Westaway D. Transgenic mouse models of Alzhei¬mer's disease. Physiol Behav 2001;73:873-886. (Pubitemid 32885575)
-
(2001)
Physiology and Behavior
, vol.73
, Issue.5
, pp. 873-886
-
-
Janus, C.1
Westaway, D.2
-
25
-
-
77956057086
-
Murine models of Alzheimer's disease and their use in developing immunotherapies
-
Wisniewski T, Sigurdsson EM. Murine models of Alzheimer's disease and their use in developing immunotherapies. Biochim Biophys Acta 2010;1802:847-859.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 847-859
-
-
Wisniewski, T.1
Sigurdsson, E.M.2
-
26
-
-
77749315540
-
Animal models of amyloid-beta-related pathol-ogies in Alzheimer's disease
-
Philipson O, Lord A, Gumucio A, O'Callaghan P, Lannfelt L, Nilsson LN. Animal models of amyloid-beta-related pathol-ogies in Alzheimer's disease. FEBS J 2010;277:1389-1409.
-
(2010)
FEBS J
, vol.277
, pp. 1389-1409
-
-
Philipson, O.1
Lord, A.2
Gumucio, A.3
O'Callaghan, P.4
Lannfelt, L.5
Nilsson, L.N.6
-
27
-
-
64549150594
-
Natural non-trasgenic animal models for research in Alzheimer's disease
-
Sarasa M, Pesini P. Natural non-trasgenic animal models for research in Alzheimer's disease. Curr Alzheimer Res 2009; 6:171-178.
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 171-178
-
-
Sarasa, M.1
Pesini, P.2
-
28
-
-
0034594462
-
Region-specific age at onset of β-amyloid in dogs
-
DOI 10.1016/S0197-4580(00)00093-2, PII S0197458000000932
-
Head E, McCleary R, Hahn FF, Milgram NW, Cotman CW. Region-specific age at onset of beta-amyloid in dogs. Neurobiol Aging 2000;21:89-96. (Pubitemid 30224790)
-
(2000)
Neurobiology of Aging
, vol.21
, Issue.1
, pp. 89-96
-
-
Head, E.1
McCleary, R.2
Hahn, F.F.3
Milgram, N.W.4
Cotman, C.W.5
-
29
-
-
0029937437
-
The canine as an animal model of human aging and dementia
-
DOI 10.1016/0197-4580(95)02060-8
-
Cummings BJ, Head E, Ruehl W, Milgram NW, Cotman CW. The canine as an animal model of human aging and dementia. Neurobiol Aging 1996;17:259-268. (Pubitemid 26167637)
-
(1996)
Neurobiology of Aging
, vol.17
, Issue.2
, pp. 259-268
-
-
Cummings, B.J.1
Head, E.2
Ruehl, W.3
Milgram, N.W.4
Cotman, C.W.5
-
30
-
-
3242763888
-
A comparative study of age-related brain pathology - Are neurodegenerative diseases present in nonhuman animals?
-
DOI 10.1016/j.mehy.2003.12.047, PII S0306987704001410
-
Nakayama H, Uchida K, Doi K. A comparative study of age-related brain pathology-are neurodegenerative diseases present in nonhuman animals? Med Hypotheses 2004;63:198-202. (Pubitemid 38968715)
-
(2004)
Medical Hypotheses
, vol.63
, Issue.2
, pp. 198-202
-
-
Nakayama, H.1
Uchida, K.2
Doi, K.3
-
31
-
-
39049181276
-
Diffuse beta-amyloid plaques and hyperphosphorylated tau are unrelated processes in aged dogs with behavioral deficits
-
Pugliese M, Mascort J, Mahy N, Ferrer I. Diffuse beta-amyloid plaques and hyperphosphorylated tau are unrelated processes in aged dogs with behavioral deficits. Acta Neuropathol 2006;112:175-183.
-
(2006)
Acta Neuropathol
, vol.112
, pp. 175-183
-
-
Pugliese, M.1
Mascort, J.2
Mahy, N.3
Ferrer, I.4
-
32
-
-
0030582387
-
Amino- and carboxyl-terminal heterogeneity of β-amyloid peptides deposited in human brain
-
DOI 10.1016/S0304-3940(96)12970-0
-
Saido TC, Yamao-Harigaya W, Iwatsubo T, Kawashima S. Amino-and carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain. Neurosci Lett 1996;215: 173-176. (Pubitemid 26323454)
-
(1996)
Neuroscience Letters
, vol.215
, Issue.3
, pp. 173-176
-
-
Saido, T.C.1
Yamao-Harigaya, W.2
Iwatsubo, T.3
Kawashima, S.4
-
33
-
-
0030064140
-
Amyloid β protein deposition in normal aging has the same characteristics as that in Alzheimer's disease: Predominance of Aβ42(43) and association of Aβ40 with cored plaques
-
Fukumoto H, Asami-Odaka A, Suzuki N, Shimada H, Ihara Y, Iwatsubo T. Amyloid beta protein deposition in normal aging has the same characteristics as that in Alzheimer's disease. predominance of A beta 42(43) and association of A beta 40 with cored plaques. Am J Pathol 1996;148:259-265. (Pubitemid 26019660)
-
(1996)
American Journal of Pathology
, vol.148
, Issue.1
, pp. 259-265
-
-
Fukumoto, H.1
Asami-Odaka, A.2
Suzuki, N.3
Shimada, H.4
Ihara, Y.5
Iwatsubo, T.6
-
34
-
-
26644445247
-
β-amyloid is different in normal aging and in Alzheimer disease
-
DOI 10.1074/jbc.M501694200
-
Piccini A, Russo C, Gliozzi A, Relini A, Vitali A, Borghi R, Giliberto L, Armirotti A, D'Arrigo C, Bachi A, et al. Beta-amyloid is different in normal aging and in Alzheimer disease. J Biol Chem 2005;280:34186-34192. (Pubitemid 41443143)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.40
, pp. 34186-34192
-
-
Piccini, A.1
Russo, C.2
Gliozzi, A.3
Relini, A.4
Vitali, A.5
Borghi, R.6
Giliberto, L.7
Armirotti, A.8
D'Arrigo, C.9
Bachi, A.10
Cattaneo, A.11
Canale, C.12
Torrassa, S.13
Saido, T.C.14
Markesbery, W.15
Gambetti, P.16
Tabaton, M.17
-
35
-
-
53549099647
-
Glutaminyl cyclase inhibition attenuates pyroglu-tamate abeta and Alzheimer's disease-like pathology
-
Schilling S, Zeitschel U, Hoffmann T, Heiser U, Francke M, Kehlen A, Holzer M, Hutter-Paier B, Prokesch M, Windisch M, et al. Glutaminyl cyclase inhibition attenuates pyroglu-tamate abeta and Alzheimer's disease-like pathology. Nat Med 2008;14:1106-1111.
-
(2008)
Nat Med
, vol.14
, pp. 1106-1111
-
-
Schilling, S.1
Zeitschel, U.2
Hoffmann, T.3
Heiser, U.4
Francke, M.5
Kehlen, A.6
Holzer, M.7
Hutter-Paier, B.8
Prokesch, M.9
Windisch, M.10
-
36
-
-
78149281327
-
Pyroglutamate-abeta: Role in the natural history of Alzheimer's disease
-
Gunn AP, Masters CL, Cherny RA. Pyroglutamate-abeta: Role in the natural history of Alzheimer's disease. Int J Biochem Cell Biol 2010;42:1915-1918.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 1915-1918
-
-
Gunn, A.P.1
Masters, C.L.2
Cherny, R.A.3
-
37
-
-
79959584705
-
Reduced levels of IgM autoantibodies against N-truncated pyroglutamate abeta in plasma of patients with Alzheimer's disease
-
in press
-
Marcello A, Wirths O, Schneider-Axmann T, Degerman-Gunnarsson M, Lannfelt L, Bayer TA. Reduced levels of IgM autoantibodies against N-truncated pyroglutamate abeta in plasma of patients with Alzheimer's disease Neurobiol Aging, in press
-
Neurobiol Aging
-
-
Marcello, A.1
Wirths, O.2
Schneider-Axmann, T.3
Degerman-Gunnarsson, M.4
Lannfelt, L.5
Bayer, T.A.6
-
38
-
-
0035748687
-
Down's syndrome. A complicated genetic insult
-
Reeves RH. Down's syndrome. A complicated genetic insult. Lancet 2001;358:Suppl:S23.
-
(2001)
Lancet
, vol.358
, Issue.SUPPL.
-
-
Reeves, R.H.1
-
39
-
-
0030742712
-
Heterogeneity of water-soluble amyloid β-peptide in Alzheimer's disease and Down's syndrome brains
-
DOI 10.1016/S0014-5793(97)00564-4, PII S0014579397005644
-
Russo C, Saido TC, DeBusk LM, Tabaton M, Gambetti P, Teller JK. Heterogeneity of water-soluble amyloid beta-peptide in Alzheimer's disease and down's syndrome brains. FEBS Lett 1997;409:411-416. (Pubitemid 27285896)
-
(1997)
FEBS Letters
, vol.409
, Issue.3
, pp. 411-416
-
-
Russo, C.1
Saido, T.C.2
DeBusk, L.M.3
Tabaton, M.4
Gambetti, P.5
Teller, J.K.6
-
40
-
-
0030101270
-
A retrospective study of canine senile plaques and cerebral amyloid angiopathy
-
Yoshino T, Uchida K, Tateyama S, Yamaguchi R, Nakayama H, Goto N. A retrospective study of canine senile plaques and cerebral amyloid angiopathy. Vet Pathol 1996;33:230-234. (Pubitemid 126484266)
-
(1996)
Veterinary Pathology
, vol.33
, Issue.2
, pp. 230-234
-
-
Yoshino, T.1
Uchida, K.2
Tateyama, S.3
Yamaguchi, R.4
Nakayama, H.5
Goto, N.6
-
41
-
-
77957279325
-
Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease
-
Portelius E, Bogdanovic N, Gustavsson MK, Volkmann I, Brinkmalm G, Zetterberg H, Winblad B, Blennow K. Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease. Acta Neuropathol 2010;120:185-193.
-
(2010)
Acta Neuropathol
, vol.120
, pp. 185-193
-
-
Portelius, E.1
Bogdanovic, N.2
Gustavsson, M.K.3
Volkmann, I.4
Brinkmalm, G.5
Zetterberg, H.6
Winblad, B.7
Blennow, K.8
-
42
-
-
0034989501
-
Commentary: Aβ N- terminal isoforms: Critical contributors in the course of AD pathophysiology
-
Tekirian TL. Commentary: Abeta N-terminal isoforms: Critical contributors in the course of AD pathophysiology. J Alzheimers Dis 2001;3:241-248. (Pubitemid 32566523)
-
(2001)
Journal of Alzheimer's Disease
, vol.3
, Issue.2
, pp. 241-248
-
-
Tekirian, T.L.1
-
43
-
-
0025853543
-
Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis
-
Johnstone EM, Chaney MO, Norris FH, Pascual R, Little SP. Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis. Brain Res Mol Brain Res 1991;10:299-305.
-
(1991)
Brain Res Mol Brain Res
, vol.10
, pp. 299-305
-
-
Johnstone, E.M.1
Chaney, M.O.2
Norris, F.H.3
Pascual, R.4
Little, S.P.5
-
44
-
-
0023118252
-
Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease
-
Selkoe DJ, Bell DS, Podlisny MB, Price DL, Cork LC. Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease. Science 1987;235:873-877. (Pubitemid 17019123)
-
(1987)
Science
, vol.235
, Issue.4791
, pp. 873-877
-
-
Selkoe, D.J.1
Bell, D.S.2
Podlisny, M.B.3
-
45
-
-
48249145775
-
Inhibition of glutaminyl cyclase prevents pGlu-abeta forma¬tion after intracortical/hippocampal microinjection in vivo/in situ
-
Schilling S, Appl T, Hoffmann T, Cynis H, Schulz K, Jagla W, Friedrich D, Wermann M, Buchholz M, Heiser U, et al. Inhibition of glutaminyl cyclase prevents pGlu-abeta forma¬tion after intracortical/hippocampal microinjection in vivo/in situ. J Neurochem 2008;106:1225-1236.
-
(2008)
J Neurochem
, vol.106
, pp. 1225-1236
-
-
Schilling, S.1
Appl, T.2
Hoffmann, T.3
Cynis, H.4
Schulz, K.5
Jagla, W.6
Friedrich, D.7
Wermann, M.8
Buchholz, M.9
Heiser, U.10
-
46
-
-
0025840609
-
Primary structure and functional expression of a glutaminyl cyclase
-
Pohl T, Zimmer M, Mugele K, Spiess J. Primary structure and functional expression of a glutaminyl cyclase. Proc Natl Acad Sci USA 1991;88:10059-10063. (Pubitemid 21915775)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.22
, pp. 10059-10063
-
-
Pohl, T.1
Zimmer, M.2
Mugele, K.3
Spiess, J.4
-
47
-
-
50849124123
-
Glutaminyl cyclases from animals and plants: A case of functionally convergent protein evolution
-
Schilling S, Wasternack C, Demuth HU. Glutaminyl cyclases from animals and plants: A case of functionally convergent protein evolution. Biol Chem 2008;389: 983-991.
-
(2008)
Biol Chem
, vol.389
, pp. 983-991
-
-
Schilling, S.1
Wasternack, C.2
Demuth, H.U.3
-
48
-
-
70350435563
-
Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics
-
Stephan A, Wermann M, von Bohlen A, Koch B, Cynis H, Demuth HU, Schilling S. Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics. FEBS J 2009;276:6522-6536.
-
(2009)
FEBS J
, vol.276
, pp. 6522-6536
-
-
Stephan, A.1
Wermann, M.2
Von Bohlen, A.3
Koch, B.4
Cynis, H.5
Demuth, H.U.6
Schilling, S.7
-
49
-
-
0033062814
-
Evidence for tissue-specific forms of glutaminyl cyclase
-
DOI 10.1016/S0014-5793(99)00872-8, PII S0014579399008728
-
Sykes PA, Watson SJ, Temple JS, Bateman RC Jr.Evidence for tissue-specific forms of glutaminyl cyclase. FEBS Lett 1999;455:159-161. (Pubitemid 29322801)
-
(1999)
FEBS Letters
, vol.455
, Issue.1-2
, pp. 159-161
-
-
Sykes, P.A.1
Watson, S.J.2
Temple, J.S.3
Bateman Jr., R.C.4
-
50
-
-
77952551031
-
Concomitant detection of beta-amyloid peptides with N-terminal truncation and different C-terminal endings in cortical plaques from cases with Alzheimer's disease, senile monkeys and triple transgenic mice
-
Hartig W, Goldhammer S, Bauer U, Wegner F, Wirths O, Bayer TA, Grosche J. Concomitant detection of beta-amyloid peptides with N-terminal truncation and different C-terminal endings in cortical plaques from cases with Alzheimer's disease, senile monkeys and triple transgenic mice. J Chem Neuroanat 2010;40:82-92.
-
(2010)
J Chem Neuroanat
, vol.40
, pp. 82-92
-
-
Hartig, W.1
Goldhammer, S.2
Bauer, U.3
Wegner, F.4
Wirths, O.5
Bayer, T.A.6
Grosche, J.7
-
51
-
-
0033578402
-
The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta
-
He W, Barrow CJ. The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. Biochemistry 1999;38:10871-10877.
-
(1999)
Biochemistry
, vol.38
, pp. 10871-10877
-
-
He, W.1
Barrow, C.J.2
-
52
-
-
67349158314
-
Amyloid-beta peptide Abetap3-42 affects early aggregation of full-length Abeta1-42
-
Sanders HM, Lust R, Teller JK. Amyloid-beta peptide Abetap3-42 affects early aggregation of full-length Abeta1-42. Peptides 2009;30:849-854.
-
(2009)
Peptides
, vol.30
, pp. 849-854
-
-
Sanders, H.M.1
Lust, R.2
Teller, J.K.3
-
53
-
-
4344580888
-
Strategies for disease modification in Alzheimer's disease
-
DOI 10.1038/nrn1495
-
Citron M. Strategies for disease modification in Alzheimer's disease. Nat Rev Neurosci 2004;5:677-685. (Pubitemid 39150139)
-
(2004)
Nature Reviews Neuroscience
, vol.5
, Issue.9
, pp. 677-685
-
-
Citron, M.1
-
54
-
-
10044232897
-
Alzheimer's disease and immunotherapy
-
Solomon B. Alzheimer's disease and immunotherapy. Curr Alzheimer Res 2004;1:149-163.
-
(2004)
Curr Alzheimer Res
, vol.1
, pp. 149-163
-
-
Solomon, B.1
-
55
-
-
0037452779
-
Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer's disease-like neuropathology
-
DOI 10.1073/pnas.0436286100
-
Bard F, Barbour R, Cannon C, Carretto R, Fox M, Games D, Guido T, Hoenow K, Hu K, Johnson-Wood K, et al. Epitope and isotype specificities of antibodies to beta-amyloid peptide for protection against Alzheimer's disease-like neuropathol-ogy. Proc Natl Acad Sci USA 2003;100:2023-2028. (Pubitemid 36254567)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.4
, pp. 2023-2028
-
-
Bard, F.1
Barbour, R.2
Cannon, C.3
Carretto, R.4
Fox, M.5
Games, D.6
Guido, T.7
Hoenow, K.8
Hu, K.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, C.13
Lee, M.14
Motter, R.15
Nguyen, M.16
Reed, A.17
Schenk, D.18
Tang, P.19
Vasquez, N.20
Seubert, P.21
Yednock, T.22
more..
-
56
-
-
0030971789
-
Disaggregation of Alzheimer β-amyloid by site-directed mAb
-
DOI 10.1073/pnas.94.8.4109
-
Solomon B, Koppel R, Frankel D, Hanan-Aharon E. Disaggregation of Alzheimer beta-amyloid by site-directed mAb. Proc Natl Acad Sci USA 1997;94:4109-4112. (Pubitemid 27180507)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.8
, pp. 4109-4112
-
-
Solomon, B.1
Koppel, R.2
Frankel, D.3
Hanan-Aharon, E.4
-
57
-
-
68049116924
-
Immunodominant epitope and properties of pyroglutamate-modified abeta-specific antibodies produced in rabbits
-
Acero G, Manoutcharian K, Vasilevko V, Munguia ME, Govezensky T, Coronas G, Luz-Madrigal A, Cribbs DH, Gevorkian G. Immunodominant epitope and properties of pyroglutamate-modified abeta-specific antibodies produced in rabbits. J Neuroimmunol 2009;213:39-46.
-
(2009)
J Neuroimmunol
, vol.213
, pp. 39-46
-
-
Acero, G.1
Manoutcharian, K.2
Vasilevko, V.3
Munguia, M.E.4
Govezensky, T.5
Coronas, G.6
Luz-Madrigal, A.7
Cribbs, D.H.8
Gevorkian, G.9
-
58
-
-
67749122581
-
Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease
-
Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, et al. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. Proc Natl Acad Sci USA 2009;106:12145-12150.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12145-12150
-
-
Britschgi, M.1
Olin, C.E.2
Johns, H.T.3
Takeda-Uchimura, Y.4
Lemieux, M.C.5
Rufibach, K.6
Rajadas, J.7
Zhang, H.8
Tomooka, B.9
Robinson, W.H.10
-
59
-
-
0034633632
-
Immunization against Alzheimer's beta-amyloid plaques via EFRH phage adminis-tration
-
Frenkel D, Katz O, Solomon B. Immunization against Alzheimer's beta-amyloid plaques via EFRH phage adminis-tration. Proc Natl Acad Sci USA 2000;97:11455-11459.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11455-11459
-
-
Frenkel, D.1
Katz, O.2
Solomon, B.3
-
60
-
-
43649096717
-
A two-year study with fibrillar beta-amyloid (abeta) immunization in aged canines: Effects on cognitive function and brain abeta
-
Head E, Pop V, Vasilevko V, Hill M, Saing T, Sarsoza F, Nistor M, Christie LA, Milton S, Glabe C, et al. A two-year study with fibrillar beta-amyloid (abeta) immunization in aged canines: Effects on cognitive function and brain abeta. J Neurosci 2008;28:3555-3566.
-
(2008)
J Neurosci
, vol.28
, pp. 3555-3566
-
-
Head, E.1
Pop, V.2
Vasilevko, V.3
Hill, M.4
Saing, T.5
Sarsoza, F.6
Nistor, M.7
Christie, L.A.8
Milton, S.9
Glabe, C.10
-
61
-
-
62849095583
-
Beta-amyloid cortical deposits are accompanied by the loss of serotonergic neurons in the dog
-
Bernedo V, Insua D, Suarez ML, Santamarina G, Sarasa M, Pesini P. Beta-amyloid cortical deposits are accompanied by the loss of serotonergic neurons in the dog. J Comp Neurol 2009;513:417-429.
-
(2009)
J Comp Neurol
, vol.513
, pp. 417-429
-
-
Bernedo, V.1
Insua, D.2
Suarez, M.L.3
Santamarina, G.4
Sarasa, M.5
Pesini, P.6
-
62
-
-
0030013083
-
β-amyloid accumulation correlates with cognitive dysfunction in the aged canine
-
DOI 10.1006/nlme.1996.0039
-
Cummings BJ, Head E, Afagh AJ, Milgram NW, Cotman CW. Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine. Neurobiol Learn Mem 1996; 66:11-23. (Pubitemid 26195731)
-
(1996)
Neurobiology of Learning and Memory
, vol.66
, Issue.1
, pp. 11-23
-
-
Cummings, B.J.1
Head, E.2
Afagh, A.J.3
Milgram, N.W.4
Cotman, C.W.5
-
63
-
-
0032410562
-
Visual-discrimination learning ability and β-amyloid accumulation in the dog
-
DOI 10.1016/S0197-4580(98)00084-0, PII S0197458098000840
-
Head E, Callahan H, Muggenburg BA, Cotman CW, Milgram NW. Visual-discrimination learning ability and beta-amyloid accumulation in the dog. Neurobiol Aging 1998;19:415-425. (Pubitemid 29065491)
-
(1998)
Neurobiology of Aging
, vol.19
, Issue.5
, pp. 415-425
-
-
Head, E.1
Callahan, H.2
Muggenburg, B.A.3
Cotman, C.W.4
Milgram, N.W.5
-
64
-
-
31344454617
-
Cognitive disturbances in old dogs suffering from the canine counterpart of Alzheimer's disease
-
DOI 10.1016/j.brainres.2005.11.021, PII S0006899305016021
-
Rofina JE, van Ederen AM, Toussaint MJM, Secreve M, van der Spek A, van der Meer I, van Eerdenburg FJCM, Gruys E. Cognitive disturbances in old dogs suffering from the canine counterpart of Alzheimer's disease. Brain Res 2006;1069: 216-226. (Pubitemid 43145916)
-
(2006)
Brain Research
, vol.1069
, Issue.1
, pp. 216-226
-
-
Rofina, J.E.1
Van Ederen, A.M.2
Toussaint, M.J.M.3
Secreve, M.4
Van Der Spek, A.5
Van Der Meer, I.6
Van Eerdenburg, F.J.C.M.7
Gruys, E.8
-
65
-
-
0013015637
-
Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging
-
DOI 10.1101/lm.54403
-
Tapp PD, Siwak CT, Estrada J, Head E, Muggenburg BA, Cotman CW, Milgram NW. Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging. Learn Mem 2003;10:64-73. (Pubitemid 36177022)
-
(2003)
Learning and Memory
, vol.10
, Issue.1
, pp. 64-73
-
-
Tapp, P.D.1
Siwak, C.T.2
Estrada, J.3
Head, E.4
Muggenburg, B.A.5
Cotman, C.W.6
Milgram, N.W.7
-
66
-
-
12444298979
-
Effects of age on measures of complex working memory span in the beagle dog (Canis familiaris) using two versions of a spatial list learning paradigm
-
DOI 10.1101/lm.56503
-
Tapp PD, Siwak CT, Estrada J, Holowachuk D, Milgram NW. Effects of age on measures of complex working memory span in the beagle dog (canis familiaris) using two versions of a spatial list learning paradigm. Learn Mem 2003;10:148-160. (Pubitemid 36418725)
-
(2003)
Learning and Memory
, vol.10
, Issue.2
, pp. 148-160
-
-
Tapp, P.D.1
Siwak, C.T.2
Estrada, J.3
Holowachuk, D.4
Milgram, N.W.5
-
67
-
-
17644443469
-
Pyroglutamate-modified amyloid beta-peptides-AbetaN3 (pE)-strongly affect cultured neuron and astrocyte survival
-
Russo C, Violani E, Salis S, Venezia V, Dolcini V, Damonte G, Benatti U, D'Arrigo C, Patrone E, Carlo P, et al. Pyroglutamate-modified amyloid beta-peptides-AbetaN3 (pE)-strongly affect cultured neuron and astrocyte survival. J Neurochem 2002;82:1480-1489.
-
(2002)
J Neurochem
, vol.82
, pp. 1480-1489
-
-
Russo, C.1
Violani, E.2
Salis, S.3
Venezia, V.4
Dolcini, V.5
Damonte, G.6
Benatti, U.7
D'Arrigo, C.8
Patrone, E.9
Carlo, P.10
-
68
-
-
69949135716
-
Intraneuronal pyroglutamate-abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model
-
Wirths O, Breyhan H, Cynis H, Schilling S, Demuth HU, Bayer TA. Intraneuronal pyroglutamate-abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model. Acta Neuropathol 2009;118:487-496.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 487-496
-
-
Wirths, O.1
Breyhan, H.2
Cynis, H.3
Schilling, S.4
Demuth, H.U.5
Bayer, T.A.6
-
69
-
-
0031679480
-
Cerebral amyloid angiopathy: Amyloid β accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease
-
Weller RO, Massey A, Newman TA, Hutchings M, Kuo YM, Roher AE. Cerebral amyloid angiopathy: Amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease. Am J Pathol 1998;153: 725-733. (Pubitemid 28419027)
-
(1998)
American Journal of Pathology
, vol.153
, Issue.3
, pp. 725-733
-
-
Weller, R.O.1
Massey, A.2
Newman, T.A.3
Hutchings, M.4
Kuo, Y.-M.5
Roher, A.E.6
-
70
-
-
24144443470
-
42 peptides in cerebrospinal fluid and prediction of progression of mild cognitive impairment
-
DOI 10.1373/clinchem.2005.051201
-
Vanderstichele H, De Meyer G, Andreasen N, Kostanjevecki V, Wallin A, Olsson A, Blennow K, Vanmechelen E. Amino-truncated beta-amyloid42 peptides in cerebrospinal fluid and prediction of progression of mild cognitive impairment. Clin Chem 2005;51:1650-1660. (Pubitemid 41233100)
-
(2005)
Clinical Chemistry
, vol.51
, Issue.9
, pp. 1650-1660
-
-
Vanderstichele, H.1
De Meyer, G.2
Andreasen, N.3
Kostanjevecki, V.4
Wallin, A.5
Olsson, A.6
Blennow, K.7
Vanmechelen, E.8
|