Mycobacterium ulcerans DNA not detected in Faecal samples from Buruli ulcer patients: Results of a pilot study

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Sarfo, Fred S ^a   Lavender, Caroline J ^b   Fyfe, Janet A M ^b   Johnson, Paul D R ^c,d,e   Stinear, Timothy P ^d,e   Phillips, Richard O ^a  

^a KOMFO ANOKYE TEACHING HOSPITAL   (Ghana)

^b VICTORIAN INFECTIOUS DISEASES REFERENCE LABORATORY   (Australia)

^c AUSTIN HEALTH   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL LOAD; BACTERIAL SHEDDING; BACTERIUM DETECTION; BACTERIUM IDENTIFICATION; BURULI ULCER; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE CARRIER; FECES ANALYSIS; FEMALE; GASTROINTESTINAL TRACT; HUMAN; INFANT; MALE; MYCOBACTERIUM ULCERANS; NONHUMAN; PILOT STUDY; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; SCHOOL CHILD; SENSITIVITY ANALYSIS; CASE CONTROL STUDY; FAMILY SIZE; FECES; GENETICS; MICROBIOLOGY; MIDDLE AGED; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ANIMALIA; BACTERIA (MICROORGANISMS); METATHERIA; MYCOBACTERIUM ULCERANS;

ADOLESCENT; ADULT; BURULI ULCER; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DNA, BACTERIAL; FAMILY CHARACTERISTICS; FECES; FEMALE; HUMANS; INFANT; MALE; MIDDLE AGED; MYCOBACTERIUM ULCERANS; PILOT PROJECTS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 79955786284     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019611     Document Type: Article

References (7)

1. Fyfe JA, Lavender CJ, Handasyde KA, Legione AR, O'Brien CR, et al. (2010) A major role for mammals in the ecology of Mycobacterium ulcerans. PLoS Negl Trop Dis 4: e791.
2. Johnson PD, Azuolas J, Lavender CJ, Wishart E, Stinear TP, et al. (2007) Mycobacterium ulcerans in mosquitoes captured during outbreak of Buruli ulcer, southeastern Australia. Emerg Infect Dis 13: 1653-1660.
3. Johnson PD, Lavender CJ, (2009) Correlation between Buruli ulcer and vector-borne notifiable diseases, Victoria, Australia. Emerg Infect Dis 15: 614-615.
4. Durnez L, Suykerbuyk P, Nicolas V, Barriere P, Verheyen E, et al. (2010) Terrestrial small mammals as reservoirs of Mycobacterium ulcerans in benin. Appl Environ Microbiol 76: 4574-4577.
5. Fyfe JA, Lavender CJ, Johnson PD, Globan M, Sievers A, et al. (2007) Development and application of two multiplex real-time PCR assays for the detection of Mycobacterium ulcerans in clinical and environmental samples. Appl Environ Microbiol 73: 4733-4740.
6. Roltgen K, Qi W, Ruf MT, Mensah-Quainoo E, Pidot SJ, et al. (2010) Single nucleotide polymorphism typing of Mycobacterium ulcerans reveals focal transmission of buruli ulcer in a highly endemic region of Ghana. PLoS Negl Trop Dis 4: e751.
7. Pidot S, Porter J, et al. (2010) Serological evaluation of Mycobacterium ulcerans antigens identified by comparative genomics. PLoS Negl Trop Dis In Press.