The effects of the intraamygdalar melatonin injections on the anxiety like behavior and the spatial memory performance in male Wistar rats

Behavioural Brain Research

Volumn 222, Issue 1, 2011, Pages 141-150

  Karakaş, Alper ^a   Coşkun, Hamit ^a   Kaya, Aliye ^a   Kücük, Ayşegül ^b   Gündüz, Bülent ^c  

^a ABANT IZZET BAYSAL UNIVERSITY   (Turkey)

^b DUMLUPINAR UNIVERSITY   (Turkey)

^c ÇANAKKALE ONSEKIZ MART UNIVERSITY   (Turkey)

Author keywords

Amygdala; Anxiety; Melatonin; Memory; Pineal gland

Indexed keywords

DIAZEPAM; MELATONIN; SODIUM CHLORIDE;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MEGADOSE; MALE; MAZE TEST; MENTAL PERFORMANCE; NONHUMAN; OPEN FIELD TEST; PINEALECTOMY; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

AMYGDALA; ANALYSIS OF VARIANCE; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; DIAZEPAM; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; LOCOMOTION; MALE; MAZE LEARNING; MELATONIN; MEMORY DISORDERS; RATS; RATS, WISTAR; REACTION TIME; SPACE PERCEPTION; TIME FACTORS;

EID: 79955786175     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.03.029     Document Type: Article

References (62)

1. Abrams J.K., Johnson P.L., Shekhar A., Lowry C.A. S.07.01 Anxiogenic drugs act selectively ontopographically distinct midbrain, pontine, and medullary serotonergic neurons. Eur Neuropsychopharm 2004, 14(Suppl. 3):S124.
2. Abrams J.K., Johnson P.L., Shekhar A., Lowry C.A. P.2.01 Anxiogenic drugs act selectively on topographically distinct midbrain, pontine, and medullary serotonergic neurons. Eur Neuropsychopharm 2004, 14(Suppl. 1):S21.
3. Addy N.A., Nakijama A., Levin E.D. Nicotinic mechanisms of memory: effects of acute local DH beta E and MLA infusions in the basolateral amygdale. Cognit Brain Res 2003, 16(1):51-57.
4. Almonte A.G., Hamill C.E., Chhatwal J.P., Wingo T.S., Barber J.A., Lyuboslavsky P.N., et al. Learning and memory deficits in mice lacking protease activated receptor-1. Neurobiol Learn Mem 2007, 88(3):295-304.
5. Arendt J. Melatonin, circadian rhythms and sleep. N Engl J Med 2000, 343:1114-1116.
6. Argyriou A., Prast H., Philippu A. Melatonin facilitates short-term memory. Eur J Pharmacol 1998, 349:159-162.
7. Baydas G., Nedzvetsky V.S., Nerush P.A., Ki{dotless}ri{dotless}chenko S.V., Demchenko H.M., Reiter R.J. A novel role for melatonin: regulation of the expression of cell adhesion molecules in the hippocampus, cortex and cerebellum. Neurosci Lett 2002, 326:109-112.
8. Benabid N., Mesfi{dotless}oui A., Ouichou A. Effects of photoperiod regimen on emotional behaviour in two tests for anxiolytic activity in Wistar rat. Brain Res Bull 2008.
9. Blackshear A., Yamamoto M., Anderson B.J., Holmes P.V., Lundström L., Langel U., et al. Intracerebroventricular administration of galanin or galanin receptor subtype 1 agonist M617 induces c-Fos activation in central amygdala and dorsomedial hypothalamus. Peptides 2007, 28(5):1120-1124.
10. Borjigin J., Li X., Snyder S.H. The pineal gland and melatonin: molecular and pharmacologic regulation. Annu Rev Pharmacol 1999, 39:53-65.
11. Brzezinski A. Melatonin in humans. New Engl J Med 1997, 336:186-195.
12. Cao X.J., Wang M., Chen W.H., Zhu D.M., She J.Q., Ruan D.Y. Effects of chronic administration of melatonin on spatial learning ability and long-term potentiation in lead-exposed and control rats. Biomed Environ Sci 2009, 22:70-75.
13. Cardinalli D.P., Vacas M.I., Boyer E.E. Specific binding of melatonin in bovine brain. Endocrinology 1979, 105:437-441.
14. Chapmann D.I. Seasonal changes in the gonads and accessory glands of male mammals. Mammal Rev 1970, 1:231-248.
15. Coloma F.M., Niles L.P. Melatonin enhancement of [3H]-gamma-aminobutyric acid and [3H] muscimol binding in rat brain. Biochem Pharmacol 1988, 37:1271-1274.
16. Cornélio A.M., Luiz Nunes-de-Souza R. Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze. Behav Brain Res 2007, 178(1):82-89.
17. Dawson G.R., Tricklebank M.D. Use of the elevated plus maze in the search for novel anxiolytic agents. Trends Pharmacol Sci 1995, 16(2):33-36.
18. Ekmekcioglu C. Melatonin receptors in humans: biological role and clinical relevance. Biomed Pharmacother 2006, 60:97-108.
19. El-Sherif Y., Tesoriero J., Hogan M.V., Wieraszko A. Melatonin regulates neuronal plasticity in the hippocampus. J Neurosci Res 2003, 72:454-460.
20. Ergun Y., Ergun U.G., Orhan F.O., Kucuk E. Co-administration of a nitric oxide synthase inhibitor and melatonin exerts an additive antidepressant-like effect in the mouse forced swim test. Med Sci Monit 2006, 12:307-312.
21. Golombek D.A., Pevet P., Cardinalli D.P. Melatonin effects on behavior: possible mediation by the central GABAergic system. Neurosci Biobehav Rev 1996, 20:403-412.
22. Gündüz B., Stetson M.H. A test of the coincidence and duration models of melatonin action in Siberian hamsters: the effects of one hour melatonin infusions on testicular development of intact and pinealectomized juvenile Siberian hamsters, (Phodopus sungorus). J Pineal Res 2001, 30:97-107.
23. Gündüz B., Stetson M.H. A test of the coincidence and duration models of melatonin action in Siberian hamsters: II: The effects of 4- and 8-hr melatonin infusions on testicular development of pinealectomized juvenile Siberian hamsters, (Phodopus sungorus). J Pineal Res 2001, 30:56-64.
24. Hale M.W., Bouwknecht J.A., Spiga F., Shekhar A., Lowry C.A. Exposure to high- and low-light conditions in an open-field test of anxiety increases c-Fos expression in specific subdivisions of the rat basolateral amygdaloid complex. Brain Res Bull 2006, 71(1-3):174-182.
25. Hardeland R., Pandi-Perumal S.R., Cardinali D.P. Melatonin. Int J Biochem Cell Biol 2006, 38(3):313-316.
26. Hoffman R.A., Reiter R.J. Rapid pinealectomy in hamsters and other small rodents. Anat Record 1965, 24:83-89.
27. Hong S.M., Stetson M.H. Detailed diurnal rhythm of sensitivity to melatonin injections in Turkish hamsters. Mesocricews brandsi. J Pineal Res 1987, 4:69-78.
28. Jern C., Manhem K., Eriksson E., Tengborn L., Risberg B., Jern S. Hemostatic responses to mental stress during the menstrual cycle. Thromb Haemostasis 1991, 66:614-618.
29. Juszcak M., Drobnik J., Guzek J.W., Schwarzberg H. Effect of pinealectomy and melatonin on vasopressin-potentiated passive avoidance in rats. J Physiol Pharmacol 1996, 47:621-627.
30. Karakaş A, Coşkun H, Kaya A. The effects of pinealectomy, melatonin injections and implants on the spatial memory performance of male Wistar rats. Biol Rhythm Res; , in press. doi:10.1080/09291016.2010.537443.
31. Klein D.C. The mammalian melatonin rhythm generating system. Light and biological rhythms in man 1993, 55-70. Pergamon Pres, New York. L. Watterberg (Ed.).
32. Kovács G.L., Gajari I., Telegdy G., Lissak K. Effects of melatonin and pinealectomy on avoidance and exploratory activity in the rat. Physiol Behav 1974, 13:349-355.
33. Krause D.N., Dubocovich M.L. Regulatory sites in the melatonin system of mammals. Trends Neurosci 1990, 13:464-470.
34. Loiseau F., Bihan C.L., Hamon M., Thiebot M.H. Effects of melatonin and agomelatine in anxiety-related procedures in rats: interaction with diazepam. Eur Neuropsychopharm 2006, 16:417-428.
35. Mantovani M., Pertile R., Calixto J.B., Santos A.R., Rodrigues A.L. Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-d-aspartate receptors and the l-arginine-nitric oxide pathway. Neurosci Lett 2003, 343:1-4.
36. Martinez L.A., Klann E., Tejada-Simon M.V. Translocation and activation of Rac in the hippocampus during associative contextual fear learning. Neurobiol Learn Mem 2007, 88(1):104-113.
37. Martini L. Behavioral effects of pineal principles. The pineal gland 1971, 368-372. Livingstone, Edinburgh. G.E.W. Wolsten-holme, J. Knight (Eds.).
38. Masana M.I., Dubocovich M.L. Melatonin receptor signaling: finding the path through the dark. Sci STKE 2001, pe39.
39. Mazzucchelli C., Pannacci M., Nonno R., Lucini V., Franchini F., Stankov B.M. The melatonin receptor in the human brain: cloning experiments and distribution studies. Brain Res Mol Brain Res 1996, 39:117-126.
40. McIntyre C.K., Ragozzino M.E., Gold P.E. Intra-amygdala infusions of scopolamine impair performance on a conditioned place preference task but not a spatial radial maze task. Behav Brain Res 1998, 95(2):219-226.
41. Naranjo-Rodriguez E.B., Ortiz Orsornio A., Hernandez-Avitia E., Mendoza-Fernandez V., Escobar A. Anxiolytic-like actions of melatonin, 5-methoxytryptophan, 5-hydroxytryptophol and benzodiazepines on a conflict procedure. Prog Neuropsychopharmacol Biol Psychiatry 2000, 24:117-129.
42. Niles L.P., Pickering D.S., Arciszewski M.A. Effects of chronic melatonin administration on GABA and diazepam binding in rat brain. J Neural Transm 1987, 70:117-124.
43. Papp M., Litwa E., Gruca P., Mocaer E. Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety. Behav Pharmacol 2006, 17:9-18.
44. Pickavance L., Tadayyon M., Williams G., Vernon R.G. Lactation suppresses diurnal rhythm of serum leptin. Biochem Biophys Res Commun 1998, 248:196-199.
45. Poeggeler B., Saarela S., Reiter R.J., Tan D.X., Chen L.D., Manchester L.C., et al. Melatonin, a highly potent endogeneous radical scavenger and electron donor, new aspects of the antioxidant chemistry of this indole accessed in vitro. Ann Ny Acad Sci 1994, 738. xi-xii, 1-467.
46. Pyter L.M., Nelson R.J. Enduring effects of photoperiod on affective behaviors in Siberian hamsters (Phodopus sungorus). Behav Neurosci 2006, 120(1):125-134.
47. Rasch B., Buchel C., Gais S., Born J. Odor cues during slowwave sleep prompt declarative memory consolidation. Science 2007, 315:1426-1429.
48. Reiter R.J., Poeggeler B., Tan D.X., Chen L.D., Manchester L.C., Guerro J.M. Antioxidant capacity of melatonin: a novel action not requiring a receptor. Neuroendocrinol Lett 1993, 15:103-116.
49. Rosenstein R.E., Cardinali D.P. Melatonin increases in vivo Gaba accumulation in rat hypothalamus, cerebellum, cerebral cortex and pineal gland. Brain Res 1986, 398:403-406.
50. Savaskan E., Olivieri G., Brydon L., Jockers R., Krauchi K., Wirz-Justice A., et al. Cerebrovascular melatonin MT1-receptor alterations in patients with Alzheimer's disease. Neurosci Lett 2001, 308:9-12.
51. Savaskan E., Ayoub M.A., Ravid R., Angeloni D., Franchini F., Meier F., et al. Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease. J Pineal Res 2005, 38:10-16.
52. Sinclair L., Nutt D. Anxiolytics. Psychiatry 2007, 6(7):284-288.
53. Stetson M.N., Tay D.E. Time course of sensitivity of golden hamsters to melatonin injections throughout the day. Biol Reprod 1983, 29:432-438.
54. Stetson M.N., Sarafidis E., Rollag M.D. Sensitivity of adult male Djungarian hamsters (Phodopus sungorus) to melatonin injections throughout the day: effects on the reproductive system and the pineal. Biol Reprod 1986, 35:618-632.
55. Stetson M.N., Watson-Whitmyre M. Effect of exogenous and endogenous melatonin on gonadal function in hamsters. J Neural Transm 1986, 21:55-80.
56. Sutherland R.J., Mc Donalds R.J. Hippocampus, amygdale and memory deficits. Behav Brain Res 1990, 34:57-79.
57. Tuzcu M., Baydas G. Effect of melatonin and vitamin E on diabetes-induced learning and memory impairment in rats. Eur J Pharmacol 2006, 537:106-110.
58. Vanecek J. Inhibitory effect of melatonin on GnRH induced LH release. Rev Reprod 1999, 4:67-72.
59. Watson-Whitmyre M., Stetson M.H. A mathematical method for estimating paired testes weight from in situ testicular measurements in three species of hamster. Anat Record 1985, 213:473-476.
60. Weaver D.R., Rivkees S.A., Reppert S.M. Localization and characterization of melatonin receptors in rodent brain by in vitro aotoradiography. J Neurosci 1989, 9:2581-2590.
61. Wirz-Justice A. Treatment tools in chronobiology. Rev Med Interne 2001, 22(Suppl. 1):37-38.
62. Xu F., Li J.C., Ma K.C., Wang M. Effects of melatonin on hypothalamic gamma-aminobutyric acid, aspartic acid, glutamic acid, beta-endorphin and serotonin levels in male mice. Biol Signals 1995, 4:225-231.