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Volumn 58, Issue 4, 2011, Pages 237-246

The effect of weight loss and treatment with metformin on serum vaspin levels in women with polycystic ovary syndrome

Author keywords

Metformin; Obesity; Orlistat; Polycystic ovary syndrome; Vaspin

Indexed keywords

METFORMIN; SIBUTRAMINE; TETRAHYDROLIPSTATIN; VASPIN;

EID: 79955779344     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K10E-330     Document Type: Article
Times cited : (42)

References (39)
  • 1
    • 0031456016 scopus 로고    scopus 로고
    • Insulin resistance and the polycystic ovary syndrome: Mechanism and implication for pathogenesis
    • Dunaif A (1997) Insulin resistance and the polycystic ovary syndrome: mechanism and implication for pathogenesis. Endocr Rev 18: 774-800.
    • (1997) Endocr Rev , vol.18 , pp. 774-800
    • Dunaif, A.1
  • 3
    • 38049077991 scopus 로고    scopus 로고
    • Metformin for the treatment of the polycystic ovary syndrome
    • Nestler JE (2008) Metformin for the treatment of the polycystic ovary syndrome. N Engl J Med 358: 47-54.
    • (2008) N Engl J Med , vol.358 , pp. 47-54
    • Nestler, J.E.1
  • 4
    • 0022354308 scopus 로고
    • Lipoprotein lipid concentrations and cardiovascular risk in women with polycystic ovary syndrome
    • Wild RA, Painter PC, Coulson PB, Carruth KB, Ranney GB (1985) Lipoprotein lipid concentrations and cardiovascular risk in women with polycystic ovary syndrome. J Clin Endocrinol Metab 61: 946-951.
    • (1985) J Clin Endocrinol Metab , vol.61 , pp. 946-951
    • Wild, R.A.1    Painter, P.C.2    Coulson, P.B.3    Carruth, K.B.4    Ranney, G.B.5
  • 5
    • 67651159079 scopus 로고    scopus 로고
    • The effect of pharmaceutical intervention on lipid profile in polycystic ovary syndrome
    • Diamanti-Kandarakis E, Kandaraki E, Christakou C, Panidis D (2009) The effect of pharmaceutical intervention on lipid profile in polycystic ovary syndrome. Obes Rev 10: 431-441.
    • (2009) Obes Rev , vol.10 , pp. 431-441
    • Diamanti-Kandarakis, E.1    Kandaraki, E.2    Christakou, C.3    Panidis, D.4
  • 7
    • 0034017773 scopus 로고    scopus 로고
    • The genetics of obesity. Lessons for polycystic ovary syndrome
    • Legro RS (2000) The genetics of obesity. Lessons for polycystic ovary syndrome. Ann NY Acad Sci 900: 193-202.
    • (2000) Ann NY Acad Sci , vol.900 , pp. 193-202
    • Legro, R.S.1
  • 9
    • 0023189131 scopus 로고
    • Characterization of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance, and/or hyperisulinemia
    • Dunaif A, Graf M, Mandeli J, Laumas V, Dobrjansky A (1987) Characterization of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance, and/or hyperisulinemia. J Clin Endocrinol Metab 65: 499-507.
    • (1987) J Clin Endocrinol Metab , vol.65 , pp. 499-507
    • Dunaif, A.1    Graf, M.2    Mandeli, J.3    Laumas, V.4    Dobrjansky, A.5
  • 10
    • 0024437305 scopus 로고
    • Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
    • Dunaif A, Segal KR, Futterweit W, Dobrjansky A (1989) Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes 38: 1165-1174.
    • (1989) Diabetes , vol.38 , pp. 1165-1174
    • Dunaif, A.1    Segal, K.R.2    Futterweit, W.3    Dobrjansky, A.4
  • 11
    • 33845592201 scopus 로고    scopus 로고
    • Adipose tissue-derived factors: Impact on health and disease
    • Trujillo ME, Scherer PE (2006) Adipose tissue-derived factors: impact on health and disease. Endocr Rev 27: 762-778.
    • (2006) Endocr Rev , vol.27 , pp. 762-778
    • Trujillo, M.E.1    Scherer, P.E.2
  • 12
    • 34548009557 scopus 로고    scopus 로고
    • Adiposity, type 2 diabetes and the metabolic syndrome in breast cancer (Complication of Obesity)
    • Vona-Davis L, Howard-McNatt M, Rose DP (2007) Adiposity, type 2 diabetes and the metabolic syndrome in breast cancer (Complication of Obesity). Obes Rev 8: 395-408.
    • (2007) Obes Rev , vol.8 , pp. 395-408
    • Vona-Davis, L.1    Howard-McNatt, M.2    Rose, D.P.3
  • 14
    • 0034504237 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome
    • Wajchenberg BL (2000) Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 21: 697-738.
    • (2000) Endocr Rev , vol.21 , pp. 697-738
    • Wajchenberg, B.L.1
  • 15
    • 0036179818 scopus 로고    scopus 로고
    • A pilot study of long-term effects of a novel obesity treatment: Omentectomy in connection with adjustable gastric banding
    • Thörne A, Lönnqvist F, Apelman J, Hellers G, Arner P (2002) A pilot study of long-term effects of a novel obesity treatment: omentectomy in connection with adjustable gastric banding. Int J Obes Relat Metab Disord 26: 193-199.
    • (2002) Int J Obes Relat Metab Disord , vol.26 , pp. 193-199
    • Thörne, A.1    Lönnqvist, F.2    Apelman, J.3    Hellers, G.4    Arner, P.5
  • 19
    • 0346186090 scopus 로고    scopus 로고
    • Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)
    • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group
    • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group (2004) Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 19: 41-47.
    • (2004) Hum Reprod , vol.19 , pp. 41-47
  • 20
    • 0346725827 scopus 로고    scopus 로고
    • Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome
    • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group
    • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group (2004) Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 81: 19-25.
    • (2004) Fertil Steril , vol.81 , pp. 19-25
  • 21
    • 41749107754 scopus 로고    scopus 로고
    • Obesity, weight loss, and the polycystic ovary syndrome: Effect of treatment with diet and orlistat for 24 weeks on insulin resistance and androgen levels
    • Panidis D, Farmakiotis D, Rousso D, Kourtis A, Katsikis I, Krassas G (2008) Obesity, weight loss, and the polycystic ovary syndrome: effect of treatment with diet and orlistat for 24 weeks on insulin resistance and androgen levels. Fertil Steril 89: 899-906.
    • (2008) Fertil Steril , vol.89 , pp. 899-906
    • Panidis, D.1    Farmakiotis, D.2    Rousso, D.3    Kourtis, A.4    Katsikis, I.5    Krassas, G.6
  • 22
    • 42149164248 scopus 로고    scopus 로고
    • Effect of hypocaloric diet plus sibutramine treatment on hormonal and metabolic features in overweight and obese women with polycystic ovary syndrome: A randomized, 24-week study
    • Florakis D, Diamanti-Kandarakis E, Katsikis I, Nassis GP, Karkanaki A, Georgopoulos N, Panidis D (2008) Effect of hypocaloric diet plus sibutramine treatment on hormonal and metabolic features in overweight and obese women with polycystic ovary syndrome: a randomized, 24-week study. Int J Obesity 32: 692-699.
    • (2008) Int J Obesity , vol.32 , pp. 692-699
    • Florakis, D.1    Diamanti-Kandarakis, E.2    Katsikis, I.3    Nassis, G.P.4    Karkanaki, A.5    Georgopoulos, N.6    Panidis, D.7
  • 23
    • 60849107731 scopus 로고    scopus 로고
    • Anti-Müllerian hormone levels reflect severity of PCOS but are negatively influenced by obesity: Relationship with increased luteinizing hormone levels
    • Piouka A, Farmakiotis D, Katsikis I, Macut D, Gerou S, Panidis D (2009) Anti-Müllerian hormone levels reflect severity of PCOS but are negatively influenced by obesity: relationship with increased luteinizing hormone levels. Am J Physiol Endocrinol Metab 296: E238-243.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Piouka, A.1    Farmakiotis, D.2    Katsikis, I.3    Macut, D.4    Gerou, S.5    Panidis, D.6
  • 24
    • 0036257524 scopus 로고    scopus 로고
    • Evaluation of assays available to measure free testosterone
    • Morley JE, Patrick P, Perry HM (2002) Evaluation of assays available to measure free testosterone. Metabolism 51: 554-559.
    • (2002) Metabolism , vol.51 , pp. 554-559
    • Morley, J.E.1    Patrick, P.2    Perry, H.M.3
  • 25
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews D, Hosker J, Rudenski A, Naylor B, Treacher D, Turner R (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 12-19.
    • (1985) Diabetologia , vol.28 , pp. 12-19
    • Matthews, D.1    Hosker, J.2    Rudenski, A.3    Naylor, B.4    Treacher, D.5    Turner, R.6
  • 26
    • 0034456568 scopus 로고    scopus 로고
    • Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans
    • Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, Quon MJ (2000) Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 85: 2402-2410.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2402-2410
    • Katz, A.1    Nambi, S.S.2    Mather, K.3    Baron, A.D.4    Follmann, D.A.5    Sullivan, G.6    Quon, M.J.7
  • 27
    • 0021985069 scopus 로고
    • α1-Antitrypsin and the serpins: Variation and countervariation
    • Carrell R, Travis J (1985) α1-Antitrypsin and the serpins: variation and countervariation. Trends Bioch Sci 10: 20-24.
    • (1985) Trends Bioch Sci , vol.10 , pp. 20-24
    • Carrell, R.1    Travis, J.2
  • 28
    • 0036882395 scopus 로고    scopus 로고
    • Serpin structure, mechanism, and function
    • Gettins PG (2002) Serpin structure, mechanism, and function. Chem Rev 102: 4751-4804.
    • (2002) Chem Rev , vol.102 , pp. 4751-4804
    • Gettins, P.G.1
  • 29
    • 20444503356 scopus 로고    scopus 로고
    • Formation of a large, complex domain of histone hyperacetylation at human 14q32.1 requires the serpin locus control region
    • Baxter EW, Cummings WJ, Fournier REK (2005) Formation of a large, complex domain of histone hyperacetylation at human 14q32.1 requires the serpin locus control region. Nucleic Acids Res 33: 3313-3322.
    • (2005) Nucleic Acids Res , vol.33 , pp. 3313-3322
    • Baxter, E.W.1    Cummings, W.J.2    Fournier, R.E.K.3
  • 30
    • 0033778883 scopus 로고    scopus 로고
    • Identification of genes specifically expressed in the accumulated visceral adipose tissue of OLETF rats
    • Hida K, Wada J, Zhang H, Hiragushi K, Tsuchiyama Y, Shikata K, Makino H (2000) Identification of genes specifically expressed in the accumulated visceral adipose tissue of OLETF rats. J Lipid Res 41: 1615-1622.
    • (2000) J Lipid Res , vol.41 , pp. 1615-1622
    • Hida, K.1    Wada, J.2    Zhang, H.3    Hiragushi, K.4    Tsuchiyama, Y.5    Shikata, K.6    Makino, H.7
  • 31
    • 48249120025 scopus 로고    scopus 로고
    • Metformin decreases the adipokine Vaspin in overweight women with polycystic ovary concomitant with improvement in insulin sensitivity and a decrease in insulin resistance
    • Tan BK, Heutling D, Chen J, Farhatullah S, Adya R, Keay SD, Kennedy CR, Lehnert H, Randeva HS (2008) Metformin decreases the adipokine Vaspin in overweight women with polycystic ovary concomitant with improvement in insulin sensitivity and a decrease in insulin resistance. Diabetes 57: 1501-1507.
    • (2008) Diabetes , vol.57 , pp. 1501-1507
    • Tan, B.K.1    Heutling, D.2    Chen, J.3    Farhatullah, S.4    Adya, R.5    Keay, S.D.6    Kennedy, C.R.7    Lehnert, H.8    Randeva, H.S.9
  • 32
    • 64549129225 scopus 로고    scopus 로고
    • Serum visceral adipose tissue-derived serine protease inhibitor concentrations in human obesity and polycystic ovary syndrome
    • Escobar-Morreale HF, Luque-Ramirez M, San-Millan JL (2009) Serum visceral adipose tissue-derived serine protease inhibitor concentrations in human obesity and polycystic ovary syndrome. Diabetes Care 32: e6.
    • (2009) Diabetes Care , vol.32
    • Escobar-Morreale, H.F.1    Luque-Ramirez, M.2    San-Millan, J.L.3
  • 33
    • 79953876780 scopus 로고    scopus 로고
    • Serum vaspin and C-reactive protein levels in women with polycystic ovaries and polycystic ovary syndrome
    • epub ahead of print
    • Cakal E, Ustun Y, Engin-Ustun Y, Ozkaya M, Kilinc M (2010) Serum vaspin and C-reactive protein levels in women with polycystic ovaries and polycystic ovary syndrome. Gynecol Endocrinol epub ahead of print.
    • (2010) Gynecol Endocrinol
    • Cakal, E.1    Ustun, Y.2    Engin-Ustun, Y.3    Ozkaya, M.4    Kilinc, M.5
  • 34
    • 0027495982 scopus 로고
    • The impact of metformin therapy on hepatic glucose production and skeletal muscle glycogen synthase activity in overweight type II diabetic patients
    • Johnson AB, Webster JM, Sum CF, Heseltine L, Argyraki M, Cooper BG, Taylor R (1993) The impact of metformin therapy on hepatic glucose production and skeletal muscle glycogen synthase activity in overweight type II diabetic patients. Metabolism 42: 1217-1222.
    • (1993) Metabolism , vol.42 , pp. 1217-1222
    • Johnson, A.B.1    Webster, J.M.2    Sum, C.F.3    Heseltine, L.4    Argyraki, M.5    Cooper, B.G.6    Taylor, R.7
  • 37
    • 0030783316 scopus 로고    scopus 로고
    • Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens
    • Nestler JE, Jakubowicz DJ (1997) Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens. J Clin Endocrinol Metab 82: 4075-4079.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4075-4079
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 39
    • 38049077991 scopus 로고    scopus 로고
    • Metformin for the treatment of the polycystic ovary syndrome
    • Nestler JE (2008) Metformin for the treatment of the polycystic ovary syndrome. N Engl J Med 358: 47-54.
    • (2008) N Engl J Med , vol.358 , pp. 47-54
    • Nestler, J.E.1


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