Diagnosing variant Creutzfeldt - Jakob disease: A retrospective analysis of the first 150 cases in the UK

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 82, Issue 6, 2011, Pages 646-651

  Heath, C A ^a   Cooper, S A ^b   Murray, K ^a   Lowman, A ^c   Henry, C ^d   MacLeod, M A ^e   Stewart, G ^a   Zeidler, M ^f   McKenzie, J M ^g   Knight, R S G ^g   Will, R G ^g  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b SOUTHERN GENERAL HOSPITAL   (United Kingdom)

^c UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^d MERCY UNIVERSITY HOSPITAL   (Ireland)

^e ABERDEEN ROYAL INFIRMARY   (United Kingdom)

^f VICTORIA HOSPITAL   (United Kingdom)

^g UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOPSY; BRAIN BIOPSY; BRAIN DISEASE; BRAIN INFECTION; CHILD; CLINICAL FEATURE; CONSULTATION; DEMYELINATING DISEASE; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; DISEASE DURATION; DISEASE SURVEILLANCE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG ABUSE; EARLY DIAGNOSIS; FEMALE; FRIEDREICH ATAXIA; HUMAN; HUNTINGTON CHOREA; INTESTINE LIPODYSTROPHY; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MEDICAL RECORD REVIEW; MENTAL DISEASE; METABOLIC DISORDER; NERVOUS SYSTEM INFLAMMATION; NEUROACANTHOCYTOSIS; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; ONSET AGE; PARANEOPLASTIC SYNDROME; PORPHYRIA; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SEX RATIO; SKULL INJURY; SPINOCEREBELLAR DEGENERATION; SPORADIC CREUTZFELDT JAKOB DISEASE; SURVIVAL RATE; UNITED KINGDOM; VARIANT CREUTZFELDT JAKOB DISEASE; VASCULITIS; WILSON DISEASE;

EID: 79955759823     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2010.232264     Document Type: Article

References (21)

1. Will RG, Ironside JW, Zeidler M, et al. A new variant of Creutzfeldt - Jakob disease in the UK. Lancet 1996;347:921-5.
2. Will RG, Stewart GE, Zeidler M, et al. Psychiatric features of new variant Creutzfeldt - Jakob disease. Psychiatr Bull 1999;23:264-7. (Pubitemid 29221834)
3. Myles S, Douglas MJ, Ward HJT, et al. Variant Creutzfeldt - Jakob disease: costs borne by families. Health Soc Care Commun 2002;10:91-8. (Pubitemid 36844221)
4. Phillips N. The BSE Inquiry. London: The Stationery Office, 2000.
5. Zeidler M, Stewart GE, Barraclough CR, et al. New variant Creutzfeldt - Jakob disease: neurological features and diagnostic tests. Lancet 1997;350:903-7. (Pubitemid 27420525)
6. Trevitt CR, Collinge J. A systematic review of prion therapeutics in experimental models. Brain 2006;129:2241-65. (Pubitemid 44522112)
7. Spencer MD, Knight RSG, Will RG. First hundred cases of variant Creutzfeldt - Jakob disease: retrospective case note review of early psychiatric and neurological features. BMJ 2002;324:1479-82. (Pubitemid 34666613)
8. Will RG, Zeidler M, Stewart GE, et al. Diagnosis of new variant Creutzfeldt - Jakob disease. Ann Neurol 2000;47:575-82. (Pubitemid 30261892)
9. World Health Organisation. WHO manual for surveillance of human transmissible spongiform encephalopathies including variant CJD. Geneva: WHO, 2003.
10. Cousens S, Smith PG, Ward H, et al. Geographical distribution of variant Creutzfeldt - Jakob disease in Great Britain, 1994-2000. Lancet 2001;357:1002-7.
11. Lepine J, Gastpar M, Mendlwicz J, et al. Depression in the community: The first paneuropean study. Int Clin Psychopharmacol 1997;12:19-29.
12. ABN. UK Neurology: The Next Ten Years. London: Association of British Neurologists, 2003.
13. Collie DA, Summers DM, Sellar RJ, et al. Diagnosing variant Creutzfeldt - Jakob disease with the pulvinar sign: MR imaging findings in 86 neuropathologically confirmed cases. AJNR Am J Neuroradiol 2003;24:1560-9. (Pubitemid 37151720)
14. Hill AF, Zeidler M, Ironside J, et al. Diagnosis of new variant Creutzfeldt - Jakob disease by tonsil biopsy. Lancet 1997;349:99-100. (Pubitemid 27023429)
15. Weller B, Knight R, Will R. An overview of the care issues for Creutzfeldt - Jakob disease. Eur J Palliative Care 2003;10:5-8.
16. Knight R. Therapeutic possibilities in CJD: patents 1996-1999. Exp Opin Ther Patents 2000;10:49-57.
17. Llewelyn CA, Hewitt PE, Knight RSG, et al. Possible transmission of variant Creutzfeldt - Jakob disease by blood transfusion. Lancet 2004;363:417-21. (Pubitemid 38210057)
18. Peden AH, Head MW, Ritchie DL, et al. Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient. Lancet 2004;364:527-9. (Pubitemid 39070413)
19. Wroe SJ, Pal S, Siddique D, et al. Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt - Jakob disease associated with blood transfusion: a case report. Lancet 2006;368:2061-7. (Pubitemid 44855106)
20. Health Protection Agency. Fourth case of transfusion-associated variant-CJD infection. Health Protection Report 2007;1(3). www.hpa.org.uk.
21. National Institute for Health and Clinical Excellence. Patient safety and reduction of risk of transmission of Creutzfeldt - Jakob disease (CJD) via interventional procedures, 2006.