Hyperbaric hyperoxia reduces exercising forearm blood flow in humans

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 300, Issue 5, 2011, Pages

  Casey, Darren P ^a   Joyner, Michael J ^a   Claus, Paul L ^a   Curry, Timothy B ^a  

^a MAYO CLINIC   (United States)

Author keywords

Blood; Flow; Muscle; Skeletal

Indexed keywords

ARM BLOOD FLOW; ARM EXERCISE; ARTICLE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CARDIOVASCULAR RESPONSE; CLINICAL ARTICLE; CONTROLLED STUDY; DOPPLER FLOWMETRY; FEMALE; HEART MUSCLE FIBER MEMBRANE CONDUCTANCE; HEART OUTPUT; HEART RATE; HUMAN; HYPERBARIC OXYGEN; HYPEREMIA; HYPEROXIA; MALE; MEAN ARTERIAL PRESSURE; MUSCLE BLOOD FLOW; PRIORITY JOURNAL;

ADULT; BLOOD PRESSURE; EXERCISE; FEMALE; FOREARM; HUMANS; HYPERBARIC OXYGENATION; HYPEROXIA; MALE; MUSCLE, SKELETAL; OXYGEN; REGIONAL BLOOD FLOW; ULTRASONOGRAPHY, DOPPLER;

EID: 79955759208     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00165.2011     Document Type: Article

References (39)

1. Bachofen M, Gage A, Bachofen H. Vascular response to changes in blood oxygen tension under various blood flow rates. Am J Physiol 220: 1786-1792, 1971.
2. Bird AD, Telfer AB. The effect of oxygen at 1 and 2 atmospheres on resting forearm blood flow. Surg Gynecol Obstet 123: 260-268, 1966.
3. Calbet JA, Boushel R, Radegran G, Sondergaard H, Wagner PD, Saltin B. Determinants of maximal oxygen uptake in severe acute hypoxia. Am J Physiol Regul Integr Comp Physiol 284: R291-R303, 2003.
4. Casey DP, Curry TB, Wilkins BW, Joyner MJ. Nitric oxide-mediated vasodilation becomes independent of -adrenergic receptor activation with increased intensity of hypoxic exercise. J Appl Physiol 110: 687-694, 2011.
5. Casey DP, Madery BD, Curry TB, Eisenach JH, Wilkins BW, Joyner MJ. Nitric oxide contributes to the augmented vasodilatation during hypoxic exercise. J Physiol 588: 373-385, 2010.
6. Casey DP, Madery BD, Pike TL, Eisenach JH, Dietz NM, Joyner MJ, Wilkins BW. Adenosine receptor antagonist and augmented vasodilation during hypoxic exercise. J Appl Physiol 107: 1128-1137, 2009.
7. CO2 during immersed prone exercise at 4.7 ATA. J Appl Physiol 106: 316-325, 2009.
8. 2. J Appl Physiol 30: 753-763, 1971.
9. Dufour SP, Patel RP, Brandon A, Teng X, Pearson J, Barker H, Ali L, Yuen AH, Smolenski RT, Gonzalez-Alonso J. Erythrocyte-dependent regulation of human skeletal muscle blood flow: role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin, and ATP. Am J Physiol Heart Circ Physiol 299: H1936-H1946, 2010.
10. Ellsworth ML, Ellis CG, Goldman D, Stephenson AH, Dietrich HH, Sprague RS. Erythrocytes: oxygen sensors and modulators of vascular tone. Physiology 24: 107-116, 2009.
11. Gonzalez-Alonso J, Olsen DB, Saltin B. Erythrocyte and the regulation of human skeletal muscle blood flow and oxygen delivery: role of circulating ATP. Circ Res 91: 1046-1055, 2002.
12. Hansen J, Sander M, Hald CF, Victor RG, Thomas GD. Metabolic modulation of sympathetic vasoconstriction in human skeletal muscle: role of tissue hypoxia. J Physiol 527: 387-396, 2000.
13. Hansen M, Madsen J. Estimation of relative changes in resting muscle blood flow by 133Xe washout: the effect of oxygen. Scand J Clin Lab Invest 31: 133-139, 1973.
14. Houssiere A, Najem B, Cuylits N, Cuypers S, Naeije R, van de Borne P. Hyperoxia enhances metaboreflex sensitivity during static exercise in humans. Am J Physiol Heart Circ Physiol 291: H210-H215, 2006.
15. Jagger JE, Bateman RM, Ellsworth ML, Ellis CG. Role of erythrocyte in regulating local O2 delivery mediated by hemoglobin oxygenation. Am J Physiol Heart Circ Physiol 280: H2833-H2839, 2001.
16. Kaijser L. Limiting factors for aerobic muscle performance. The influence of varying oxygen pressure and temperature. Acta Physiol Scand Suppl 346: 1-96, 1970.
17. Kenmure AC, Murdoch WR, Hutton I, Cameron AJ. Hemodynamic effects of oxygen at 1 and 2 Ata pressure in healthy subjects. J Appl Physiol 32: 223-226, 1972.
18. Krix M, Weber MA, Krakowski-Roosen H, Huttner HB, Delorme S, Kauczor HU, Hildebrandt W. Assessment of skeletal muscle perfusion using contrast-enhanced ultrasonography. J Ultrasound Med 24: 431-441, 2005.
19. McDowall DG, Ledingham IM, Tindal S. Alveolar-arterial gradients for oxygen at 1, 2, and 3 atmospheres absolute. J Appl Physiol 24: 324-329, 1968.
20. McMahon TJ, Moon RE, Luschinger BP, Carraway MS, Stone AE, Stolp BW, Gow AJ, Pawloski JR, Watke P, Singel DJ, Piantadosi CA, Stamler JS. Nitric oxide in the human respiratory cycle. Nat Med 8: 711-717, 2002.
21. Pasgaard T, Stankevicius E, Jorgensen MM, Ostergaard L, Simonsen U, Frobert O. Hyperoxia reduces basal release of nitric oxide and contracts porcine coronary arteries. Acta Physiol (Oxf) 191: 285-296, 2007.
22. Reich T, Tuckman J, Naftchi NE, Jacobson JH. Effect of normo- and hyperbaric oxygenation on resting and postexercise calf blood flow. J Appl Physiol 28: 275-278, 1970.
23. 2max in the exercisetrained human quadriceps. J Appl Physiol 86: 1048-1053, 1999.
24. 2 content and tension in regulation of cardiac output and leg blood flow during exercise in humans. Am J Physiol Heart Circ Physiol 276: H438-H445, 1999.
25. Rowell LB, Saltin B, Kiens B, Christensen NJ. Is peak quadriceps blood flow in humans even higher during exercise with hypoxemia? Am J Physiol Heart Circ Physiol 251: H1038-H1044, 1986.
26. Seals DR, Johnson DG, Fregosi RF. Hyperoxia lowers sympathetic activity at rest but not during exercise in humans. Am J Physiol Regul Integr Comp Physiol 260: R873-R878, 1991.
27. Sprague RS, Ellsworth ML, Stephenson AH, Kleinhenz ME, Lonigro AJ. Deformation-induced ATP release from red blood cells requires CFTR activity. Am J Physiol Heart Circ Physiol 275: H1726-H1732, 1998.
28. Sprague RS, Ellsworth ML, Stephenson AH, Lonigro AJ. Participation of cAMP in a signal-transduction pathway relating erythrocyte deformation to ATP release. Am J Physiol Cell Physiol 281: C1158-C1164, 2001.
29. Weaver LK, Howe S. Normobaric measurement of arterial oxygen tension in subjects exposed to hyperbaric oxygen. Chest 102: 1175-1181, 1992.
30. Weaver LK, Howe S, Snow GL, Deru K. Arterial and pulmonary arterial hemodynamics and oxygen delivery/extraction in normal humans exposed to hyperbaric air and oxygen. J Appl Physiol 107: 336-345, 2009.
31. Welch HG, Bonde-Petersen F, Graham T, Klausen K, Secher N. Effects of hyperoxia on leg blood flow and metabolism during exercise. J Appl Physiol 42: 385-390, 1977.
32. Wesseling KH, Jansen JR, Settels JJ, Schreuder JJ. Computation of aortic flow from pressure in humans using a nonlinear, three-element model. J Appl Physiol 74: 2566-2573, 1993.
33. Whalen RE, Saltzman HA, Holloway DH Jr, McIntosh HD, Sieker HO, Brown IW Jr. Cardiovascular and blood gas responses to hyperbaric oxygenation. Am J Cardiol 15: 638-646, 1965.
34. Wilkins BW, Pike TL, Martin EA, Curry TB, Ceridon ML, Joyner MJ. Exercise intensity-dependent contribution of beta-adrenergic receptor- mediated vasodilatation in hypoxic humans. J Physiol 586: 1195-1205, 2008.
35. Wilkins BW, Schrage WG, Liu Z, Hancock KC, Joyner MJ. Systemic hypoxia and vasoconstrictor responsiveness in exercising human muscle. J Appl Physiol 101: 1343-1350, 2006.
36. Win TS, Marshall JM. Contribution of prostaglandins to the dilation that follows isometric forearm contraction in human subjects: effects of aspirin and hyperoxia. J Appl Physiol 99: 45-52, 2005.
37. Yamauchi K, Tsutsui Y, Endo Y, Sagawa S, Yamazaki F, Shiraki K. Sympathetic nervous and hemodynamic responses to lower body negative pressure in hyperbaria in men. Am J Physiol Regul Integr Comp Physiol 282: R38-R45, 2002.
38. Yamazaki F, Takahara K, Sone R, Johnson JM. Influence of hyperoxia on skin vasomotor control in normothermic and heat-stressed humans. J Appl Physiol 103: 2026-2033, 2007.
39. Zhilyaev SY, Moskvin AN, Platonova TF, Gutsaeva DR, Churilina IV, Demchenko IT. Hyperoxic vasoconstriction in the brain is mediated by inactivation of nitric oxide by superoxide anions. Neurosci Behav Physiol 33: 783-787, 2003.