Toxic effects of dietary methylmercury on immune system development in nestling American kestrels (Falco sparverius)

Environmental Toxicology and Chemistry

Volumn 30, Issue 6, 2011, Pages 1328-1337

  Fallacara, Dawn M ^a   Halbrook, Richard S ^a   French, John B ^b  

^a SOUTHERN ILLINOIS UNIVERSITY   (United States)

^b PATUXENT WILDLIFE RESEARCH CENTER   (United States)

Author keywords

Falco sparverius; Histology; Immunotoxicity; Kestrel; Methylmercury

Indexed keywords

ADAPTIVE IMMUNITY; B CELLS; DIETARY METHYLMERCURY; DOSE-DEPENDENT; FALCO SPARVERIUS; FUNCTIONAL ASSAYS; HEALTH EFFECTS; HEMAGGLUTINATION ASSAYS; HISTOLOGICAL PARAMETERS; IMMUNE FUNCTION; IMMUNE RESPONSE; IMMUNE SYSTEMS; IMMUNOCOMPETENCE; IMMUNOTOXICITY; KESTREL; LYMPHOCYTE POPULATION; METHYL MERCURY; SHEEP RED BLOOD CELLS; SPLEEN TISSUES; T CELLS; TOXIC EFFECT; WHITE PULPS;

ANTIBODIES; ASSAYS; BLOOD; HISTOLOGY; IMMUNOLOGY; MERCURY COMPOUNDS; TISSUE; TOXICITY;

CELLS;

METHYLMERCURY;

ANTIBODY; BLOOD; CAPTIVITY; DOSE-RESPONSE RELATIONSHIP; HISTOLOGY; IMMUNE RESPONSE; METHYLMERCURY; NESTLING; RAPTOR; TOXIC MATERIAL;

ADAPTIVE IMMUNITY; AMERICAN KESTREL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; BIRD; CELLULAR IMMUNITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPLETION; DEVELOPMENT; DIETARY INTAKE; FALCO SPARVERIUS; FEMALE; HEMAGGLUTINATION TEST; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOCOMPETENCE; IMMUNOREGULATION; IMMUNOTOXICITY; LYMPHOCYTE PROLIFERATION; MALE; NESTLING; NONHUMAN; PREDATOR; PRIORITY JOURNAL; SPLEEN; T LYMPHOCYTE SUBPOPULATION; THYMUS;

ANIMALS; ANTIBODY FORMATION; B-LYMPHOCYTES; BURSA OF FABRICIUS; DIET; ENVIRONMENTAL POLLUTANTS; FALCONIFORMES; IMMUNE SYSTEM; IMMUNITY, CELLULAR; MALE; METHYLMERCURY COMPOUNDS; SPLEEN; T-LYMPHOCYTES; THYMUS GLAND;

AVES; FALCO SPARVERIUS; OVIS ARIES;

EID: 79955717782     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.519     Document Type: Article

References (34)

1. Thaxton P, Parkhurst CR. 1973. Toxicity of mercury to young chickens: changes in immunological responsiveness. Poult Sci 52: 761-764.
2. Bridger MA, Thaxton JP. 1983. Humoral immunity in the chicken as affected by mercury. Arch Environ Contam Toxicol 12: 45-49.
3. World Health Organization. 1990. Methylmercury, Vol 101 International Programme on Chemical Safety. World Health Organization, Geneva, Switzerland.
4. Druet P. 1995. Metal-induced autoimmunity. Hum Exp Toxicol 14: 120-121.
5. Lawrence DA, McCabe MJ Jr. 2002. Immunomodulation by metals. Int Immunopharmacol 2: 293-302.
6. Bennett PM, Jepson PD, Law RJ, Jones BR, Kuiken T, Baker JR, Rogan E, Kirkwood JK. 2001. Exposure to heavy metals and infectious disease mortality in harbor porpoises from England and Wales. Environ Pollut 112: 33-40.
7. Lalancette A, Morin Y, Measures L, Fournier M. 2003. Contrasting changes of sensitivity by lymphocytes and neutrophils to mercury in developing grey seals. Dev Comp Immunol 27: 735-747.
8. Spalding MG, Frederick PC, McGill HC, Boton SN, Rishey L, Schumacher LM, Blackmore CGM, Harrison J. 2000. Histologic, neurologic, and immunologic effects of methylmercury in captive great egrets. J Wildl Dis 36: 423-435.
9. Kenow KP, Grasman KA, Hines RK, Meyer MW, Gendron-Fitzpatrick A, Spalding MG, Gray BR. 2007. Effects of methylmercury exposure on the immune function of juvenile common loons (Gavia immer). Environ Toxicol Chem 26: 1460-1469.
10. Henny CJ, Hill EF, Hoffman DJ, Spalding MG, Grove RA. 2002. Nineteenth Century mercury: Hazard to wading birds and cormorants of the Carson River, Nevada. Ecotoxicology 11: 213-231.
11. Spalding MG, Bjork RD, Powell GVN, Sundlof SF. 1994. Mercury and cause of death in great white herons. J Wildl Manage 58: 735-739.
12. Daoust PY, Conboy G, McBurney S, Burgess N. 1998. Interactive mortality factors in common loons from Maritime Canada. J Wildl Dis 34: 524-531.
13. Stone WB, Okoniewki JC. 2001. Necropsy findings and environmental contaminants in common loons from New York. J Wildl Dis 37: 178-184.
14. Cristol DA, Brasso RL, Condon AM, Fovargue RE, Friedman SL, Hallinger KK, Monroe AP, White AE. 2008. The movement of aquatic mercury through terrestrial food webs.Science 320: 335.
15. Harris HH, Pickering IJ, George GN. 2003. The chemical form of mercury in fish. Science 301: 1203.
16. Nacci D, Pelletier M, Lake J, Bennett R, Nichols J, Haebler R, Grear J, Kuhn A, Copeland J, Nicholson M, Walters S, Munns WR Jr. 2005. An approach to predict risks to wildlife populations from mercury and other stressors. Ecotoxicology 14: 283-293.
17. Albers PH, Koterba MT, Rossman R, Link WA, French JB, Bennett RS, Bauer WC. 2007. Effects of methylmercury on reproduction in American kestrels. Environ Toxicol Chem 26: 1856-1866.
18. Birge WJ, Balck JA, Westerman AG, Hudson JE. 1979. The effects of mercury on reproduction of fish and amphibians. In Nriagu JO, ed, The Biogeochemistry of Mercury in the Environment. Elsevier/North Holland Biomedical, New York, NY, USA, pp 629-655.
19. Richner H, Christe P, Oppliger A. 1995. Paternal investment affects the prevalence of malaria. Proc Natl Acad Sci U S A 92: 1192-1194.
20. Apanius V. 1998. Ontogeny of immune function. In Matthias J, Ricklefs RE, eds Avian Growth and Development: Evolution Within the Altricial-Precocial Spectrum. Oxford University Press, New York, NY, USA, pp 203-221.
21. Rose ME, Orlans E, Butress N. 1981. Lymphatic system. In King AS, McLell J, eds. Form and Function in Birds. Academic, New York, NY, USA, pp 341-384.
22. Hodges RD. 1974. The Histology of the Fowl. Academic, London, United Kingdom.
23. Li X, Nakano T, Sunwoo HH, Paek BH, Chae HS, Sim JS. 1998. Effects of egg and yolk weights on yolk antibody (IgY) production in laying chickens. Poult Sci 77: 66-270.
24. Evers DC, Burgess NM, Champoux L, Hoskins B, Major A, Goodale WM, Taylor RJ, Poppenga RH, Daiglet T. 2005. Patterns and interpretation of mercury exposure in freshwater avian communities in northeastern North America. Ecotoxicology 14: 193-222.
25. Rimmer CC, McFarland KP, Evers DC, Miller EK, Aubry Y, Busby D, Taylor RJ. 2005. Mercury levels in Bichnell's thrush and other insectivorous passerines in montaine forests of the Northeastern United States and Canada. Ecotoxicology 14: 223-240.
26. Wolfe M, Norman D. 1998. Effects of waterborne mercury on terrestrial wildlife at Clear Lake: Evaluation and testing of a predictive model. Environ Toxicol Chem 17: 214-227.
27. Burger J, Gochfeld M. 1992. Trace element distribution in growing feathers: Additional excretion in feather sheaths. Arch Environ Contam Toxicol 23: 105-108.
28. Evers DC, Kaplan JD, Meyer MW, Raman PS, Braselton WE, Major A, Burgess N, Scheumhammer AM. 1998. Geographic trend in mercury measured in common loon feather and blood. Environ Toxicol Chem 17: 173-183.
29. Bearhop S, Ruxton GD, Furness RW. 2000. Dynamics of mercury in blood and feathers of great skuas. Environ Toxicol Chem 19: 1638-1643.
30. Clarkson TW, Magos L. 2006. The toxicology of mercury and its chemical compounds. Crit Rev Toxicol 36: 609-662.
31. Smits JE, Bortolotti GR, Marchant TA. 1999. Simplifying the phytohaemagglutinin skin-testing technique in studies of avian immunocompetence. Funct Ecol 13: 567-572.
32. Smits JEG, Baos R. 2005. Evaluation of the antibody mediated immune response in nestling kestrels (Falco sparverius). Dev Comp Immunol 29: 161-170.
33. Romanoff AL, Romanoff AJ. 1949. The Avian Egg. Macmillan, New York, NY, USA.
34. Romanoff AL, Romanoff AJ. 1960. The Avian Embryo. Macmillan, New York, NY, USA.