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Volumn 6, Issue 4, 2011, Pages

The human splice variant δ16HER2 induces rapid tumor onset in a reporter transgenic mouse

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; FIREFLY LUCIFERASE; HOMODIMER; ISOPROTEIN; PROTEIN KINASE P60; DISULFIDE; ERBB2 PROTEIN, MOUSE; HER2 PROTEIN, HUMAN;

EID: 79955712254     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018727     Document Type: Article
Times cited : (68)

References (21)
  • 1
    • 0024337144 scopus 로고
    • Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
    • Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, et al. (1989) Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244: 707-712.
    • (1989) Science , vol.244 , pp. 707-712
    • Slamon, D.J.1    Godolphin, W.2    Jones, L.A.3    Holt, J.A.4    Wong, S.G.5
  • 2
    • 0023713558 scopus 로고
    • Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
    • Muller WJ, Sinn E, Pattengale PK, Wallace R, Leder P, (1988) Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 54: 105-115.
    • (1988) Cell , vol.54 , pp. 105-115
    • Muller, W.J.1    Sinn, E.2    Pattengale, P.K.3    Wallace, R.4    Leder, P.5
  • 3
    • 0026472124 scopus 로고
    • Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease
    • Guy CT, Webster MA, Schaller M, Parsons TJ, Cardiff RD, et al. (1992) Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc Natl Acad Sci U S A 89: 10578-10582.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 10578-10582
    • Guy, C.T.1    Webster, M.A.2    Schaller, M.3    Parsons, T.J.4    Cardiff, R.D.5
  • 4
    • 0027986757 scopus 로고
    • Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors
    • Siegel PM, Dankort DL, Hardy WR, Muller WJ, (1994) Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors. Mol Cell Biol 14: 7068-7077.
    • (1994) Mol Cell Biol , vol.14 , pp. 7068-7077
    • Siegel, P.M.1    Dankort, D.L.2    Hardy, W.R.3    Muller, W.J.4
  • 5
    • 0345016446 scopus 로고    scopus 로고
    • Human ErbB-2 (Her-2) transgenic mice: a model system for testing Her-2 based vaccines
    • Piechocki MP, Ho YS, Pilon S, Wei WZ, (2003) Human ErbB-2 (Her-2) transgenic mice: a model system for testing Her-2 based vaccines. J Immunol 171: 5787-5794.
    • (2003) J Immunol , vol.171 , pp. 5787-5794
    • Piechocki, M.P.1    Ho, Y.S.2    Pilon, S.3    Wei, W.Z.4
  • 6
    • 11144354476 scopus 로고    scopus 로고
    • HER2-targeted therapy reduces incidence and progression of midlife mammary tumors in female murine mammary tumor virus huHER2-transgenic mice
    • Finkle D, Quan ZR, Asghari V, Kloss J, Ghaboosi N, et al. (2004) HER2-targeted therapy reduces incidence and progression of midlife mammary tumors in female murine mammary tumor virus huHER2-transgenic mice. Clin Cancer Res 10: 2499-2511.
    • (2004) Clin Cancer Res , vol.10 , pp. 2499-2511
    • Finkle, D.1    Quan, Z.R.2    Asghari, V.3    Kloss, J.4    Ghaboosi, N.5
  • 7
    • 67649234062 scopus 로고    scopus 로고
    • A naturally occurring HER2 carboxy-terminal fragment promotes mammary tumor growth and metastasis
    • Pedersen K, Angelini PD, Laos S, Bach-Faig A, Cunningham MP, et al. (2009) A naturally occurring HER2 carboxy-terminal fragment promotes mammary tumor growth and metastasis. Mol Cell Biol 29: 3319-3331.
    • (2009) Mol Cell Biol , vol.29 , pp. 3319-3331
    • Pedersen, K.1    Angelini, P.D.2    Laos, S.3    Bach-Faig, A.4    Cunningham, M.P.5
  • 8
    • 0001889163 scopus 로고    scopus 로고
    • A novel splice variant of HER2 with increased transformation activity
    • Kwong KY, Hung MC, (1998) A novel splice variant of HER2 with increased transformation activity. Mol Carcinog 23: 62-68.
    • (1998) Mol Carcinog , vol.23 , pp. 62-68
    • Kwong, K.Y.1    Hung, M.C.2
  • 9
    • 0033561296 scopus 로고    scopus 로고
    • Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer
    • Siegel PM, Ryan ED, Cardiff RD, Muller WJ, (1999) Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer. EMBO J 18: 2149-2164.
    • (1999) EMBO J , vol.18 , pp. 2149-2164
    • Siegel, P.M.1    Ryan, E.D.2    Cardiff, R.D.3    Muller, W.J.4
  • 10
    • 68849092790 scopus 로고    scopus 로고
    • An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance
    • Mitra D, Brumlik MJ, Okamgba SU, Zhu Y, Duplessis TT, et al. (2009) An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance. Mol Cancer Ther 8: 2152-2162.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2152-2162
    • Mitra, D.1    Brumlik, M.J.2    Okamgba, S.U.3    Zhu, Y.4    Duplessis, T.T.5
  • 12
    • 0029997433 scopus 로고    scopus 로고
    • Activated neu induces rapid tumor progression
    • Guy CT, Cardiff RD, Muller WJ, (1996) Activated neu induces rapid tumor progression. J Biol Chem 271: 7673-7678.
    • (1996) J Biol Chem , vol.271 , pp. 7673-7678
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 13
    • 7944233465 scopus 로고    scopus 로고
    • Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis
    • Silva CM, (2004) Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis. Oncogene 23: 8017-8023.
    • (2004) Oncogene , vol.23 , pp. 8017-8023
    • Silva, C.M.1
  • 15
    • 0003799070 scopus 로고
    • Manipulating the mouse embryo: a laboratory manual
    • Press CSHL, editor
    • Hogan BCF, Lacy E, (1986) Manipulating the mouse embryo: a laboratory manual.; Press CSHL, editor.
    • (1986)
    • Hogan, B.C.F.1    Lacy, E.2
  • 16
    • 77449123702 scopus 로고    scopus 로고
    • A restriction enzyme-PCR-based technique to determine transgene insertion sites
    • Bryda EC, Bauer BA, A restriction enzyme-PCR-based technique to determine transgene insertion sites. Methods Mol Biol 597: 287-299.
    • Methods Mol Biol , vol.597 , pp. 287-299
    • Bryda, E.C.1    Bauer, B.A.2
  • 17
    • 34047208826 scopus 로고    scopus 로고
    • Method for detection and identification of multiple chromosomal integration sites in transgenic animals created with lentivirus
    • Bryda EC, Pearson M, Agca Y, Bauer BA, (2006) Method for detection and identification of multiple chromosomal integration sites in transgenic animals created with lentivirus. Biotechniques 41: 715-719.
    • (2006) Biotechniques , vol.41 , pp. 715-719
    • Bryda, E.C.1    Pearson, M.2    Agca, Y.3    Bauer, B.A.4
  • 18
    • 84934443370 scopus 로고    scopus 로고
    • Determination of transgene copy number by real-time quantitative PCR
    • Shepherd CT, Moran Lauter AN, Scott MP, (2009) Determination of transgene copy number by real-time quantitative PCR. Methods Mol Biol 526: 129-134.
    • (2009) Methods Mol Biol , vol.526 , pp. 129-134
    • Shepherd, C.T.1    Moran Lauter, A.N.2    Scott, M.P.3
  • 19
    • 37849018693 scopus 로고    scopus 로고
    • Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress
    • Zatyka M, Ricketts C, da Silva Xavier G, Minton J, Fenton S, et al. (2008) Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress. Hum Mol Genet 17: 190-200.
    • (2008) Hum Mol Genet , vol.17 , pp. 190-200
    • Zatyka, M.1    Ricketts, C.2    da Silva Xavier, G.3    Minton, J.4    Fenton, S.5
  • 20
    • 77956942676 scopus 로고    scopus 로고
    • Carbon monoxide suppresses membrane expression of TLR4 via myeloid differentiation factor-2 in betaTC3 cells
    • Rocuts F, Ma Y, Zhang X, Gao W, Yue Y, et al. (2010) Carbon monoxide suppresses membrane expression of TLR4 via myeloid differentiation factor-2 in betaTC3 cells. J Immunol 185: 2134-2139.
    • (2010) J Immunol , vol.185 , pp. 2134-2139
    • Rocuts, F.1    Ma, Y.2    Zhang, X.3    Gao, W.4    Yue, Y.5
  • 21
    • 34347231323 scopus 로고    scopus 로고
    • Host perforin reduces tumor number but does not increase survival in oncogene-driven mammary adenocarcinoma
    • Street SE, Zerafa N, Iezzi M, Westwood JA, Stagg J, et al. (2007) Host perforin reduces tumor number but does not increase survival in oncogene-driven mammary adenocarcinoma. Cancer Res 67: 5454-5460.
    • (2007) Cancer Res , vol.67 , pp. 5454-5460
    • Street, S.E.1    Zerafa, N.2    Iezzi, M.3    Westwood, J.A.4    Stagg, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.