A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal

American Journal of Emergency Medicine

Volumn 29, Issue 4, 2011, Pages 382-385

  Hendey, Gregory W ^a   Dery, Robert A ^a   Barnes, Randy L ^a   Snowden, Brandy ^a   Mentler, Philippe ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORDIAZEPOXIDE; LORAZEPAM; PHENOBARBITAL;

ADULT; ALCOHOL WITHDRAWAL; ARTICLE; CLINICAL ARTICLE; CLINICAL INSTITUTE WITHDRAWAL ASSESSMENT SCORE; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TREATMENT FAILURE; EMERGENCY WARD; FEMALE; FOLLOW UP; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; LENGTH OF STAY; MALE; PATIENT COMPLIANCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RELAPSE; SCORING SYSTEM; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ALCOHOL-RELATED DISORDERS; CHLORDIAZEPOXIDE; FEMALE; GABA MODULATORS; HUMANS; INJECTIONS, INTRAVENOUS; LENGTH OF STAY; LORAZEPAM; MALE; MIDDLE AGED; PHENOBARBITAL; PROSPECTIVE STUDIES; RECURRENCE; SUBSTANCE WITHDRAWAL SYNDROME; TREATMENT OUTCOME;

EID: 79955697855     PISSN: 07356757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajem.2009.10.010     Document Type: Article

References (9)

1. Su M. Alcohol withdrawal. In: Wolfson A, editor. Harwood Nuss' clinical practice of emergency medicine. 4th ed. Philadelphia: Lippincott, Williams, and Wilkins; 2005. p. 1466-70.
2. Ives TJ, et al. Pharmacokinetic dosing of phenobarbital in the treatment of alcohol withdrawal syndrome. South Med J 1991;84:1.
3. Mariani JJ, Rosenthal RN, Tross S, Singh P, Anand OP. A randomized, open-label, controlled trial of gabapentin and phenobarbital in the treatment of alcohol withdrawal. Am J Addict 2006;15(1):76-84. (Pubitemid 43207192)
4. Mayo-Smith MF. Pharmacological management of alcohol withdrawal. A meta-analysis and evidence-based practice guideline. American Society of Addiction Medicine Working Group on Pharmacological Management of Alcohol Withdrawal. JAMA 1997;278(2):144-51.
5. Young G, Rores C, Murphy C, Dailey R. Intravenous phenobarbital for alcohol withdrawal and convulsions. Ann Emerg Med 1987;16:847-50. (Pubitemid 17105031)
6. Hayner CE, Wuestefeld NL, Bolton PJ. Phenobarbital treatment in a patient with resistant alcohol withdrawal syndrome. Pharmacotherapy 2009;29(7):875-8.
7. Bird RD, Makela EH. Alcohol withdrawal: what is the benzodiazepine of choice? Ann Pharmacother 1994;28(1):67-71.
8. Foy A, March S, Drinkwater V. Use of an objective clinical scale in the assessment and management of alcohol withdrawal. Alcohol Clin Exp Res 1988;12:360-4.
9. Sullivan J, Sydora K, Schneiderman J, et al. Assessment of Alcohol Withdrawal: the Revised Clinical Institute Withdrawal Assessment for Alcohol scale (CIWA-Ar). Br J Addict 1989;84:1353-7. (Pubitemid 19281139)