Methadone-induced torsade de pointes

American Journal of Emergency Medicine

Volumn 29, Issue 4, 2011, Pages 476.e1-476.e2

  Nordt, Sean Patrick ^a   Zilberstein, Jeffrey ^b   Gold, Barry ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; MAGNESIUM; METHADONE; MORPHINE SULFATE; POTASSIUM;

ADULT; ARTICLE; CASE REPORT; CHRONIC PAIN; DEFIBRILLATION; DRUG SAFETY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSPNEA; ELECTROCARDIOGRAM; EMERGENCY WARD; HEART ARRHYTHMIA; HEART PALPITATION; HOLTER MONITORING; HUMAN; INTENSIVE CARE UNIT; MALE; NEUROPATHIC PAIN; PATIENT MONITORING; PHYSICAL EXAMINATION; POLYMORPHIC VENTRICULAR TACHYCARDIA; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; QT INTERVAL; SINGLE DRUG DOSE; SYNCOPE; TORSADE DES POINTES;

EID: 79955680601     PISSN: 07356757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajem.2010.04.023     Document Type: Article

References (5)

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3. Lamont P, Hunt SC. A twist on torsade: a prolonged QT interval on methadone. J Gen Intern Med 2006;21:C9-C12. (Pubitemid 44506863)
4. Lin C, Somberg T, Molnar J, et al. The effects of chiral isolates of methadone on the cardiac potassium channel IKr. Cardiology 2009;113:59-65.
5. Krantz MJ, Kutinsky IB, Robertson AD, et al. Dose-related effects of methadone on QT prolongation in series of patients with torsade de pointes. Pharmacotherapy 2003;23:802-5. (Pubitemid 36629083)