Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 383, Issue 5, 2011, Pages 471-481

  Jackman, Katherine A ^a   Brait, Vanessa H ^a   Wang, Yutang ^b   Maghzal, Ghassan J ^b   Ball, Helen J ^b   McKenzie, Gavin ^c   De Silva, T Michael ^a   Stocker, Roland ^b   Sobey, Christopher G ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Aminoguanidine; Indoleamine 2,3 dioxygenase; Kynurenine; Stroke; Tryptophan; Vascular

Indexed keywords

1 METHYL DEXTRO TRYPTOPHAN; AMINOGUANIDINE; INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE 1; INDOLEAMINE 2,3 DIOXYGENASE INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; KYNURENINE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BRAIN FUNCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPERFUSION INJURY; STROKE; SWELLING; WILD TYPE;

ANIMALS; ARTERIOLES; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GUANIDINES; IMMUNOHISTOCHEMISTRY; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; ISCHEMIC ATTACK, TRANSIENT; KYNURENINE; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; NITRIC OXIDE SYNTHASE TYPE II; REPERFUSION INJURY; TRYPTOPHAN;

EID: 79955678168     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-011-0611-4     Document Type: Article

References (49)

1. Andre C, O'Connor JC, Kelley KW, Lestage J, Dantzer R, Castanon N (2008) Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2, 3-dioxygenase in response to peripheral lipopolysaccharide administration. J Neuroimmunol 200:90-99
2. Austin CJ, Mailu BM, Maghzal GJ, Sanchez-Perez A, Rahlfs S, Zocher K, Yuasa HJ, Arthur JW, Becker K, Stocker R, Hunt NH, Ball HJ (2010) Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2, 3-dioxygenase-2. Amino Acids 39:565-578
3. Ball HJ, Sanchez-Perez A, Weiser S, Austin CJD, Astelbauer F, Miu J, McQuillan JA, Stocker R, Jermiin LS, Hunt NH (2007) Characterization of an indoleamine 2, 3-dioxygenase-like protein found in humans and mice. Gene 396:203-213 (Pubitemid 46818792)
4. Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H (1986) Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17:472-476 (Pubitemid 16085691)
5. Brait VH, Jackman KA, Walduck A, Selemidis S, Diep H, Mast AE, Broughton BRS, Drummond GR, Sobey CG (2010) Mechanisms contributing to cerebral infarct size after stroke - gender, reperfusion, T lymphocytes and Nox2-derived superoxide. J Cereb Blood Flow Metab 30:1306-1317
6. Darlington LG, Mackay GM, Forrest CM, Stoy N, George C, Stone TW (2007) Altered kynurenine metabolism correlates with infarct volume in stroke. Eur J Neurosci 26:2211-2221 (Pubitemid 47620487)
7. Eastman CL, Guilarte TR (1989) Cytotoxicity of 3-hydroxykynurenine in a neuronal hybrid cell line. Brain Res 495:225-231 (Pubitemid 19213559)
8. Freitag S, Schachner M, Morellini F (2003) Behavioral alterations in mice deficient for the extracellular matrix glycoprotein tenascin- R. Behav Brain Res 145:189-207 (Pubitemid 37188644)
9. Gigler G, Szenasi G, Simo A, Levay G, Harsing LG Jr, Sas K, Vecsei L, Toldi J (2007) Neuroprotective effect of L-kynurenine sulfate administered before focal cerebral ischemia in mice and global cerebral ischemia in gerbils. Eur J Pharmacol 564:116-122 (Pubitemid 46946855)
10. Guillemin GJ, Kerr SJ, Smythe GA, Smith DG, Kapoor V, Armati PJ, Croitoru J, Brew BJ (2001) Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection. J Neurochem 78:842-853 (Pubitemid 32777985)
11. Guillemin GJ, Smythe G, Takikawa O, Brew BJ (2005) Expression of indoleamine 2, 3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons. Glia 49:15-23 (Pubitemid 40023649)
12. Guillemin GJ, Cullen KM, Lim CK, Smythe GA, Garner B, Kapoor V, Takikawa O, Brew BJ (2007) Characterization of the kynurenine pathway in human neurons. J Neurosci 27:12884-12892 (Pubitemid 350161746)
13. Haber R, Bessette D, Hulihan-Giblin B, Durcan MJ, Goldman D (1993) Identification of tryptophan 2, 3-dioxygenase RNA in rodent brain. J Neurochem 60:1159-1162 (Pubitemid 23066742)
14. Hansen AM, Driussi C, Turner V, Takikawa O, Hunt NH (2000) Tissue distribution of indoleamine 2, 3-dioxygenase in normal and malaria-infected tissue. Redox Rep 5:112-115 (Pubitemid 30487979)
15. Hansen AM, Ball HJ, Mitchell AJ, Miu J, Takikawa O, Hunt NH (2004) Increased expression of indoleamine 2, 3-dioxygenase in murine malaria infection is predominantly localised to the vascular endothelium. Int J Parasitol 34:1309-1319 (Pubitemid 39469988)
16. Hirata F, Hayaishi O (1975) Studies on indoleamine 2, 3-dioxygenase. I. Superoxide anion as substrate. J Biol Chem 250:5960-5966
17. Hoshi M, Saito K, Murakami Y, Taguchi A, Fujigaki H, Tanaka R, Takemura M, Ito H, Hara A, Seishima M (2009) Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following transient global ischemia in mouse. Neurosci Res 63:194-198
18. Hou DY, Muller AJ, Sharma MD, DuHadaway J, Banerjee T, Johnson M, Mellor AL, Prendergast GC, Munn DH (2007) Inhibition of indoleamine 2, 3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses. Cancer Res 67:792-801 (Pubitemid 46192220)
19. Iadecola C, Zhang F, Casey R, Nagayama M, Ross ME (1997) Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene. J Neurosci 17:9157-9164 (Pubitemid 27498443)
20. Ikegami S, Harada A, Hirokawa N (2000) Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice. Neurosci Lett 279:129-132 (Pubitemid 30069810)
21. Jackman KA, Miller AA, De Silva TM, Crack PJ, Drummond GR, Sobey CG (2009) Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice. Brit J Pharmacol 156:680-688
22. Kanai M, Nakamura T, Funakoshi H (2009) Identification and characterization of novel variants of the tryptophan 2, 3- dioxygenase gene: differential regulation in the mouse nervous system during development. Neurosci Res 64:111-117
23. Maghzal GJ, Thomas SR, Hunt NH, Stocker R (2008) Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2, 3-dioxygenase in human cells. J Biol Chem 283:12014-12025
24. Mellor AL, Baban B, Chandler P, Marshall B, Jhaver K, Hansen A, Koni PA, Iwashima M, Munn DH (2003) Cutting edge: induced indoleamine 2, 3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion. J Immunol 171:1652-1655
25. Metz R, Duhadaway JB, Kamasani U, Laury-Kleintop L, Muller AJ, Prendergast GC (2007) Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2, 3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res 67:7082-7087 (Pubitemid 47206533)
26. Miller AA, Dusting GJ, Roulston CL, Sobey CG (2006a) NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke. Brain Res 1111:111-116 (Pubitemid 44331177)
27. Miller CL, Llenos IC, Dulay JR, Weiss S (2006b) Upregulation of the initiating step of the kynurenine pathway in postmortem anterior cingulate cortex from individuals with schizophrenia and bipolar disorder. Brain Res 1073-1074:25-37
28. Minatogawa Y, Suzuki S, Ando Y, Tone S, Takikawa O (2003) Tryptophan pyrrole ring cleavage enzymes in placenta. Adv Exp Med Biol 527:425-434 (Pubitemid 38197671)
29. Ohnishi T, Hirata F, Hayaish O (1977) Indoleamine 2, 3-dioxygenase. Potassium superoxide as substrate. J Biol Chem 252:4643-4647 (Pubitemid 8155986)
30. Osada T, Ikegami S, Takiguchi-Hayashi K, Yamazaki Y, Katoh-Fukui Y, Higashinakagawa T, Sakaki Y, Takeuchi T (1999) Increased anxiety and impaired pain response in puromycin-sensitive aminopeptidase gene-deficient mice obtained by a mouse genetrap method. J Neurosci 19:6068-6078 (Pubitemid 29327939)
31. Robinson CM, Shirey KA, Carlin JM (2003) Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha. J Interferon Cytokine Res 23:413-421 (Pubitemid 37034579)
32. Robinson CM, Hale PT, Carlin JM (2005) The role of IFN-gamma and TNF-alpha-responsive regulatory elements in the synergistic induction of indoleamine dioxygenase. J Interferon Cytokine Res 25:20-30 (Pubitemid 40105588)
33. Robotka H, Sas K, Agoston M, Rozsa E, Szenasi G, Gigler G, Vecsei L, Toldi J (2008) Neuroprotection achieved in the ischaemic rat cortex with L-kynurenine sulphate. Life Sci 82:915-919
34. Roy EJ, Takikawa O, Kranz DM, Brown AR, Thomas DL (2005) Neuronal localization of indoleamine 2, 3-dioxygenase in mice. Neurosci Lett 387:95-99 (Pubitemid 41134205)
35. Saito K, Nowak TS Jr, Markey SP, Heyes MP (1993a) Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia. J Neurochem 60:180-192 (Pubitemid 23006716)
36. Saito K, Nowak TS Jr, Suyama K, Quearry BJ, Saito M, Crowley JS, Markey SP, Heyes MP (1993b) Kynurenine pathway enzymes in brain: responses to ischemic brain injury versus systemic immune activation. J Neurochem 61:2061-2070 (Pubitemid 23354062)
37. Sas K, Csete K, Vecsei L, Papp JG (2003) Effect of systemic administration of L-kynurenine on corticocerebral blood flow under normal and ischemic conditions of the brain in conscious rabbits. J Cardiovasc Pharmacol 42:403-409 (Pubitemid 37071697)
38. Sas K, Robotka H, Rozsa E, Agoston M, Szenasi G, Gigler G, Marosi M, Kis Z, Farkas T, Vecsei L, Toldi J (2008) Kynurenine diminishes the ischemia-induced histological and electrophysiological deficits in the rat hippocampus. Neurobiol Dis 32:302-308
39. Schwarcz R, Kohler C (1983) Differential vulnerability of central neurons of the rat to quinolinic acid. Neurosci Lett 38:85-90 (Pubitemid 13029108)
40. Stone TW (1993) Neuropharmacology of quinolinic and kynurenic acids. Pharmacol Rev 45:309-379
41. Stone TW, Perkins MN (1981) Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS. Eur J Pharmacol 72:411-412 (Pubitemid 11081065)
42. Sugimoto K, Iadecola C (2002) Effects of aminoguanidine on cerebral ischemia in mice: comparison between mice with and without inducible nitric oxide synthase gene. Neurosci Lett 331:25-28 (Pubitemid 35279374)
43. Taguchi A, Hara A, Saito K, Hoshi M, Niwa M, Seishima M, Mori H (2008) Localization and spatiotemporal expression of Ido following transient forebrain ischemia in gerbils. Brain Res 1217:78-85
44. Taniguchi T, Sono M, Hirata F, Hayaishi O, Tamura M, Hayashi K, Iizuka T, Ishimura Y (1979) Indoleamine 2, 3-dioxygenase. Kinetic studies on the binding of superoxide anion and molecular oxygen to enzyme. J Biol Chem 254:3288-3294
45. Tsuchiya D, Hong S, Kayama T, Panter SS, Weinstein PR (2003) Effect of suture size and carotid clip application upon blood flow and infarct volume after permanent and temporary middle cerebral artery occlusion in mice. Brain Res 970:131-139 (Pubitemid 36423188)
46. Wang Y, Liu H, McKenzie G, Witting PK, Stasch JP, Hahn M, Changsirivathanathamrong D, Wu BJ, Ball HJ, Thomas SR, Kapoor V, Celermajer DS, Mellor AL, Keaney JF Jr, Hunt NH, Stocker R (2010) Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nat Med 16:279-285
47. Xia CF, Smith RS Jr, Shen B, Yang ZR, Borlongan CV, Chao L, Chao J (2006) Postischemic brain injury is exacerbated in mice lacking the kinin B2 receptor. Hypertension 47:752-761 (Pubitemid 43740248)
48. Zhang F, Iadecola C (1998) Temporal characteristics of the protective effect of aminoguanidine on cerebral ischemic damage. Brain Res 802:104-110 (Pubitemid 28392161)
49. Zhao X, Ross ME, Iadecola C (2003) L-Arginine increases ischemic injury in wild-type mice but not in iNOS-deficient mice. Brain Res 966:308-311 (Pubitemid 36255594)