-
1
-
-
51849108509
-
Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF)
-
Han Z.B., Ren H., Zhao H., et al. Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF). Carcinogenesis 2008, 29:1853-1861.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1853-1861
-
-
Han, Z.B.1
Ren, H.2
Zhao, H.3
-
2
-
-
33646471404
-
Hypoxia-regulated differentiation: let's step it up a Notch
-
Sainson R.C., Harris A.L. Hypoxia-regulated differentiation: let's step it up a Notch. Trends Mol Med 2006, 12:141-143.
-
(2006)
Trends Mol Med
, vol.12
, pp. 141-143
-
-
Sainson, R.C.1
Harris, A.L.2
-
3
-
-
34247527730
-
Hypoxia-inducible factors, stem cells, and cancer
-
Keith B., Simon M.C. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007, 129:465-472.
-
(2007)
Cell
, vol.129
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
4
-
-
2342611976
-
Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules
-
Moeller B.J., Cao Y., Li C.Y., Dewhirst M.W. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. Cancer Cell 2004, 5:429-441.
-
(2004)
Cancer Cell
, vol.5
, pp. 429-441
-
-
Moeller, B.J.1
Cao, Y.2
Li, C.Y.3
Dewhirst, M.W.4
-
5
-
-
27644561755
-
Hypoxia requires notch signaling to maintain the undifferentiated cell state
-
Gustafsson M.V., Zheng X., Pereira T., et al. Hypoxia requires notch signaling to maintain the undifferentiated cell state. Dev Cell 2005, 9:617-628.
-
(2005)
Dev Cell
, vol.9
, pp. 617-628
-
-
Gustafsson, M.V.1
Zheng, X.2
Pereira, T.3
-
6
-
-
40949142209
-
The role of hypoxia-inducible factors in tumorigenesis
-
Rankin E.B., Giaccia A.J. The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ 2008, 15:678-685.
-
(2008)
Cell Death Differ
, vol.15
, pp. 678-685
-
-
Rankin, E.B.1
Giaccia, A.J.2
-
7
-
-
33644747418
-
HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth
-
Covello K.L., Kehler J., Yu H., et al. HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 2006, 20:557-570.
-
(2006)
Genes Dev
, vol.20
, pp. 557-570
-
-
Covello, K.L.1
Kehler, J.2
Yu, H.3
-
8
-
-
33747097563
-
Clinicopathologic significance of hypoxia-inducible factor 1alpha overexpression in gastric carcinomas
-
Mizokami K., Kakeji Y., Oda S., et al. Clinicopathologic significance of hypoxia-inducible factor 1alpha overexpression in gastric carcinomas. J Surg Oncol 2006, 94:149-154.
-
(2006)
J Surg Oncol
, vol.94
, pp. 149-154
-
-
Mizokami, K.1
Kakeji, Y.2
Oda, S.3
-
9
-
-
0036278899
-
Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer
-
Schindl M., Schoppmann S.F., Samonigg H., et al. Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer. Clin Cancer Res 2002, 8:1831-1837.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1831-1837
-
-
Schindl, M.1
Schoppmann, S.F.2
Samonigg, H.3
-
10
-
-
11144222884
-
Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression
-
Yoshimura H., Dhar D.K., Kohno H., et al. Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression. Clin Cancer Res 2004, 10:8554-8560.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8554-8560
-
-
Yoshimura, H.1
Dhar, D.K.2
Kohno, H.3
-
11
-
-
44049091352
-
Cancer stem cells-old concepts, new insights
-
Vermeulen L., Sprick M.R., Kemper K., et al. Cancer stem cells-old concepts, new insights. Cell Death Differ 2008, 15:947-958.
-
(2008)
Cell Death Differ
, vol.15
, pp. 947-958
-
-
Vermeulen, L.1
Sprick, M.R.2
Kemper, K.3
-
12
-
-
52549087785
-
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
-
Visvader J.E., Lindeman G.J. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008, 8:755-768.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
13
-
-
40649083081
-
Biological and genetic characteristics of tumor-initiating cells in colon cancer
-
Ieta K., Tanaka F., Haraguchi N., et al. Biological and genetic characteristics of tumor-initiating cells in colon cancer. Ann Surg Oncol 2008, 15:638-648.
-
(2008)
Ann Surg Oncol
, vol.15
, pp. 638-648
-
-
Ieta, K.1
Tanaka, F.2
Haraguchi, N.3
-
14
-
-
45549085634
-
Human colon cancer stem cells: a new paradigm in gastrointestinal oncology
-
Boman B.M., Huang E. Human colon cancer stem cells: a new paradigm in gastrointestinal oncology. J Clin Oncol 2008, 26:2828-2838.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2828-2838
-
-
Boman, B.M.1
Huang, E.2
-
15
-
-
35148888629
-
Cancer stem cells in radiation resistance
-
Rich J.N. Cancer stem cells in radiation resistance. Cancer Res 2007, 67:8980-8984.
-
(2007)
Cancer Res
, vol.67
, pp. 8980-8984
-
-
Rich, J.N.1
-
16
-
-
45849089879
-
Exploring the role of cancer stem cells in radioresistance
-
Baumann M., Krause M., Hill R. Exploring the role of cancer stem cells in radioresistance. Nat Rev Cancer 2008, 8:545-554.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 545-554
-
-
Baumann, M.1
Krause, M.2
Hill, R.3
-
17
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S., Wu Q., McLendon R.E., et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006, 444:756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
-
18
-
-
70350383057
-
Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer
-
Yasuda H., Tanaka K., Saigusa S., et al. Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer. Oncol Rep 2009, 22:709-717.
-
(2009)
Oncol Rep
, vol.22
, pp. 709-717
-
-
Yasuda, H.1
Tanaka, K.2
Saigusa, S.3
-
19
-
-
71549155909
-
Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy
-
Saigusa S., Tanaka K., Toiyama Y., et al. Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. Ann Surg Oncol 2009, 16:3488-3498.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 3488-3498
-
-
Saigusa, S.1
Tanaka, K.2
Toiyama, Y.3
-
20
-
-
70349754442
-
MTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells
-
Matsumoto K., Arao T., Tanaka K., et al. mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells. Cancer Res 2009, 69:7160-7164.
-
(2009)
Cancer Res
, vol.69
, pp. 7160-7164
-
-
Matsumoto, K.1
Arao, T.2
Tanaka, K.3
-
21
-
-
0035110959
-
Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy
-
Yoshikawa R., Kusunoki M., Yanagi H., et al. Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy. Cancer Res 2001, 61:1029-1037.
-
(2001)
Cancer Res
, vol.61
, pp. 1029-1037
-
-
Yoshikawa, R.1
Kusunoki, M.2
Yanagi, H.3
-
23
-
-
0035136377
-
Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: utility in the diagnosis of mantle cell lymphoma
-
Bijwaard K.E., Aguilera N.S., Monczak Y., et al. Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: utility in the diagnosis of mantle cell lymphoma. Clin Chem 2001, 47:195-201.
-
(2001)
Clin Chem
, vol.47
, pp. 195-201
-
-
Bijwaard, K.E.1
Aguilera, N.S.2
Monczak, Y.3
-
24
-
-
33748676449
-
Chemotherapy with preoperative radiotherapy in rectal cancer
-
Bosset J.F., Collette L., Calais G., et al. Chemotherapy with preoperative radiotherapy in rectal cancer. N Engl J Med 2006, 355:1114-1123.
-
(2006)
N Engl J Med
, vol.355
, pp. 1114-1123
-
-
Bosset, J.F.1
Collette, L.2
Calais, G.3
-
25
-
-
6044226542
-
Preoperative versus postoperative chemoradiotherapy for rectal cancer
-
Sauer R., Becker H., Hohenberger W., et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004, 351:1731-1740.
-
(2004)
N Engl J Med
, vol.351
, pp. 1731-1740
-
-
Sauer, R.1
Becker, H.2
Hohenberger, W.3
-
26
-
-
20944438740
-
Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer
-
discussion 836-838
-
Guillem J.G., Chessin D.B., Cohen A.M., et al. Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer. Ann Surg 2005, 241:829-836. discussion 836-838.
-
(2005)
Ann Surg
, vol.241
, pp. 829-836
-
-
Guillem, J.G.1
Chessin, D.B.2
Cohen, A.M.3
-
27
-
-
61749090849
-
Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy
-
Harada H., Itasaka S., Zhu Y., et al. Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy. Br J Cancer 2009, 100:747-757.
-
(2009)
Br J Cancer
, vol.100
, pp. 747-757
-
-
Harada, H.1
Itasaka, S.2
Zhu, Y.3
-
28
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
Sahlgren C., Gustafsson M.V., Jin S., et al. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci USA 2008, 105:6392-6397.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
|