Distinguishing the common components of oil- and water-based metalworking fluids for assessment of cancer incidence risk in autoworkers

American Journal of Industrial Medicine

Volumn 54, Issue 6, 2011, Pages 450-460

  Friesen, Melissa C ^a   Costello, Sadie ^a   Thurston, Sally W ^b   Eisen, Ellen A ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biocides; Cancer incidence; Cohort study; Endotoxin; Metalworking fluids; Nitrosamines; Polycyclic aromatic hydrocarbons

Indexed keywords

DISINFECTANT AGENT; ENDOTOXIN; METAL; NITROSAMINE; PETROLEUM; POLYCYCLIC AROMATIC HYDROCARBON; WATER;

ARTICLE; CAR; COHORT ANALYSIS; FEMALE; HUMAN; INCIDENCE; MALE; METHODOLOGY; MORTALITY; NEOPLASM; OCCUPATIONAL EXPOSURE; REGISTER; RISK ASSESSMENT; TIME; UNITED STATES;

AUTOMOBILES; COHORT STUDIES; DISINFECTANTS; ENDOTOXINS; FEMALE; HUMANS; INCIDENCE; MALE; METALS; MICHIGAN; NEOPLASMS; NITROSAMINES; OCCUPATIONAL EXPOSURE; PETROLEUM; POLYCYCLIC HYDROCARBONS, AROMATIC; REGISTRIES; RISK ASSESSMENT; TIME FACTORS; WATER;

EID: 79955663283     PISSN: 02713586     EISSN: 10970274     Source Type: Journal    
DOI: 10.1002/ajim.20932     Document Type: Article

References (42)

1. Agalliu I, Eisen EA, Kriebel D, Quinn MM, Wegman DH. 2005. A biological approach to characterizing exposure to metalworking fluids and risk of prostate cancer (United States). Cancer Causes Control 16: 323-331.
2. Agalliu I, Kriebel D, Quinn MM, Wegman DH, Eisen EA. 2007. Prostate cancer incidence in relation to time windows of exposure to metalworking fluids in the auto industry. Epidemiology 16: 664-671.
3. Applebaum KM, Malloy EJ, Eisen EA. 2007. Reducing health worker survivor bias by restricting date of hire in a cohort study of Vermont granite workers. Occup Environ Med 64: 681-687.
4. Bardin JA, Eisen EA, Tolbert PE, Hallock MF, Hammond SK, Woskie SR, Smith TJ, Monson RR. 1997. Mortality studies of machining fluid exposure in the automobile industry V: A case-control study of pancreatic cancer. Am J Ind Med 32: 240-247.
5. Blair A, Stewart P, Lubin JH, Forastier F. 2007. Methodological issues regarding confounding and exposure misclassification in epidemiological studies of occupational exposures. Am J Ind Med 50: 199-207.
6. Costello S, Friesen MC, Christiani DC, Eisen EA. 2011. Malignant melanoma and metalworking fluids in a cohort study of autoworkers. Epidemiology 22: 90-97. DOI: 10.1097/EDE.0b013e3181fce4b8 [Epub Oct 21, 2010].
7. Eisen EA, Bardin J, Gore R, Woskie SR, Hallock MF, Monson RR. 2001. Exposure-response models based on extended follow-up of a cohort mortality study in the automobile industry. Scand J Work Environ Health 27: 240-249.
8. Eisen EA, Tolbert PE, Hallock MF, Monson RR, Smith TJ, Woskie SR. 1994. Mortality studies of machining fluid exposure in the automobile industry. III: A case-control study of larynx cancer. Am J Ind Med 26: 185-202.
9. Eisen EA, Tolbert PE, Monson RR, Smith TJ. 1992. Mortality studies of machining fluid exposure in the automobile industry. I: A standardized mortality ratio analysis. Am J Ind Med 22: 809-824.
10. Friesen MC, Costello S, Eisen EA. 2009. Quantitative exposure to metalworking fluids and bladder cancer incidence in a cohort of autoworkers. Am J Epidemiol 169: 1471-1478.
11. Friesen MC, Davies HW, Teschke K, Ostry AS, Hertzman C, Demers PA. 2007. Impact of the specificity of the exposure metric on exposure-response relationships. Epidemiology 18: 88-94.
12. Hallock MF, Smith TJ, Woskie SR, Hammond SK. 1994. Estimation of historical exposures to machining fluids in the automotive industry. Am J Ind Med 26: 621-634.
13. IARC (International Agency for Research on Cancer). 1984. Polynuclear aromatic compounds, Part 3: Industrial exposures in aluminum production, coal gasification, coke production, and iron and steel founding. Lyon, France: International Agency for Research on Cancer.
14. IARC (International Agency for Research on Cancer). 1987. Polynuclear aromatic compounds, Part 2: Carbon blacks, mineral oils (lubricant base oils and derived products) and some nitroarenes. Lyon, France: International Agency for Research on Cancer.
15. IARC (International Agency for Research on Cancer). 2000. N-Nitrosodiethanolamine. Lyon, France: International Agency for Research on Cancer.
16. Kazerouni N, Thomas TL, Petralia SA, Hayes RB. 2000. Mortality among workers exposed to cutting oil mist: update of previous reports. Am J Ind Med 38: 410-416.
17. Kriebel D, Zeka A, Eisen EA, Wegman DH. 2004. Quantitative evaluation of the effects of uncontrolled confounding by alcohol and tobacco in occupational cancer studies. Int J Epidemiol 33: 1040-1045.
18. Kromhout H, Loomis DP, Kleckner RC, Savitz DA. 1997. Sensitivity of the relation between cumulative magnetic field exposure and brain cancer mortality to choice of monitoring data grouping scheme. Epidemiology 8: 442-445.
19. Lundin JI, Checkoway H. 2009. Endotoxin and cancer. Environ Health Perspect 117: 1344-1350.
20. Malloy EJ, Miller KL, Eisen EA. 2007. Rectal cancer and exposure to metalworking fluids in the automobile manufacturing industry. Occup Environ Med 64: 244-249.
21. Mehta AJ, Malloy EJ, Applebaum KM, Schwartz J, Christiani DC, Eisen EA. 2010. Reduced lung cancer mortality and exposure to synthetic fluids and biocide in the auto manufacturing industry. Scand J Work Environ Health 36: 499-508.
22. Mirer F. 2003. Updated epidemiology of workers exposed to metalworking fluids provides sufficient evidence for carcinogenicity. Appl Occup Environ Hyg 18: 902-912.
23. NIOSH (National Institute for Occupational Safety & Health). 1998. Occupational exposure to metalworking fluids. Criteria for a recommended standard. US Department of Health & Human Services. Cincinnati (OH): Public Health Service CDC. (DHHS (NIOSH). publication no 98-102).
24. Park D, Teschke K, Bartlett K. 2001. A model for predicting endotoxin concentrations in metalworking fluid sumps in small machine shops. Ann Occup Hyg 45: 569-576.
25. Park RM, Mirer FE. 1996. A survey of mortality at two automotive engine manufacturing plants. Am J Ind Med 30: 664-673.
26. Park RM, Wegman DH, Silverstein MA, Maizlish NA, Mirer FE. 1988. Causes of death among workers in a bearing manufacturing plant. Am J Ind Med 13: 569-580.
27. Savitz DA. 2003. Epidemiologic evidence on the carcinogenicity of metalworking fluids. Appl Occup Environ Hyg 18(11): 913-920.
28. Schroeder JC, Tolbert PE, Eisen EA, Monson RR, Hallock MF, Smith TJ, Woskie SR, Hammond SK, Milton DK. 1997. Mortality studies of machining fluid exposure in the automobile industry. IV: A case-control study of lung cancer. Am J Ind Med 31: 525-533.
29. Silverstein M, Park R, Marmor M, Maizlish N, Mirer F. 1988. Mortality among bearing plant workers exposed to metalworking fluids and abrasives. J Occup Med 30: 706-714.
30. Sullivan PA, Eisen EA, Woskie SR, Kriebel D, Wegman DH, Hallock MF, Hammond SK, Tolbert PE, Smith TJ, Monson RR. 1998. Mortality studies of metalworking fluid exposure in the automobile industry: VI. A case-control study of esophageal cancer. Am J Ind Med 34: 36-48.
31. Surveillance Epidemiology and End Results, National Cancer Institute. 2009. Cancer Stat Fact Sheets. Available: [accessed 23 June 2009].
32. Therneau TM, Grambsch PM. 2000. Modeling survival data: Extending the Cox model. New York, NY: Springer-Verlag.
33. Thompson D, Kriebel D, Quinn MM, Wegman DH, Eisen EA. 2005. Occupational exposure to metalworking fluids and risk of breast cancer among female autoworkers. Am J Ind Med 47: 153-160.
34. Thorne PS, DeKoster JA, Subramanian P. 1996. Environmental assessment of aerosols, bioaerosols, and airborne endotoxins in a machining plant. Am Ind Hyg Assoc J 57: 1163-1167.
35. Tolbert PE, Eisen EA, Pothier LJ, Monson RR, Hallock MF, Smith TJ. 1992. Mortality studies of machining-fluid exposure in the automobile industry. II. Risks associated with specific fluid types. Scand J Work Environ Health 18: 351-360.
36. Thurston SW, Eisen EA, Schartz J. 2002. Smoothing in survival models: an application to workers exposed to metalworking fluids. Epidemiology 13: 685-692.
37. Tolbert PE. 1997. Oils and cancer. Cancer Causes Control 8: 386-405.
38. Wernli KJ, Fitzgibbons ED, Ray RM, Gao DL, Li W, Seixas NS, Camp JE, Astrakianakis G, Feng Z, Thomas DB, Checkoway H. 2006. Occupational risk factors for esophageal and stomach cancers among female textile workers in Shanghai, China. Am J Epidemiol 163: 717-725.
39. Woskie SR, Smith TJ, Hallock MF, Hammond SK, Rosenthal F, Eisen EA, Kriebel D, Greaves IA. 1994. Size-selective pulmonary dose indices for metal-working fluid aerosols in machining and grinding operations in the automobile manufacturing industry. Am Ind Hyg Assoc J 55: 20-29.
40. Woskie SR, Virji MA, Hallock M, Smith TJ, Hammond SK. 2003. Summary of the findings from the exposure assessments for metalworking fluid mortality and morbidity studies. Appl Occup Environ Hyg 18: 855-864.
41. Zeka A, Eisen EA, Kriebel D, Gore R, Wegman DH. 2004. Risk of upper aerodigestive tract cancers in a case-cohort study of autoworkers exposed to metalworking fluids. Occup Environ Med 61: 426-431.
42. Zhao Y, Krishnadasan A, Kennedy N, Morgenstern H, Ritz B. 2005. Estimated effects of solvents and mineral oils on cancer incidence and mortality in a cohort of aerospace workers. Am J Ind Med 48: 249-258.