메뉴 건너뛰기




Volumn 85, Issue 3, 2011, Pages 698-704

Development of chitosan nanoparticles as drug delivery systems for 5-fluorouracil and leucovorin blends

Author keywords

Chitosan nanoparticles; Colon cancer; Combination chemotherapy; Drug delivery system

Indexed keywords

5-FLUOROURACIL; 5-FLUOROURACIL (5-FU); AMORPHOUS STATE; BURST RELEASE; CHITOSAN NANOPARTICLES; COLON CANCER; COMBINATION CHEMOTHERAPY; DRUG CONCENTRATION; DRUG DELIVERY SYSTEM; ELECTROSTATIC INTERACTIONS; ENCAPSULATION EFFICIENCY; FOURIER TRANSFORM SPECTROSCOPY; FTIR; HYDROPHILIC DRUGS; IN-VITRO; LOADING CAPACITIES; XRD;

EID: 79955658129     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2011.03.045     Document Type: Article
Times cited : (156)

References (21)
  • 2
    • 1842739438 scopus 로고    scopus 로고
    • A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery
    • S.C. Chen, Y.C. Wu, F.L. Mi, Y.H. Lin, L.C. Yu, and H.W. Sung A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery Journal of Controlled Release 96 2004 285 300
    • (2004) Journal of Controlled Release , vol.96 , pp. 285-300
    • Chen, S.C.1    Wu, Y.C.2    Mi, F.L.3    Lin, Y.H.4    Yu, L.C.5    Sung, H.W.6
  • 4
    • 34347324085 scopus 로고    scopus 로고
    • Chitosan nanoparticle as protein delivery carrier-Systematic examination of fabrication conditions for efficient loading and release
    • DOI 10.1016/j.colsurfb.2007.04.009, PII S0927776507001671
    • Q. Gan, and T. Wang Chitosan nanoparticle as protein delivery carrier - Systematic examination of fabrication conditions for efficient loading and release Colloids and Surfaces B: Biointerfaces 59 2007 24 34 (Pubitemid 47016920)
    • (2007) Colloids and Surfaces B: Biointerfaces , vol.59 , Issue.1 , pp. 24-34
    • Gan, Q.1    Wang, T.2
  • 5
    • 70349978292 scopus 로고    scopus 로고
    • Combination therapy: Opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines
    • F. Greco, and M.J. Vicent Combination therapy: Opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines Advanced Drug Delivery Reviews 61 2009 1203 1213
    • (2009) Advanced Drug Delivery Reviews , vol.61 , pp. 1203-1213
    • Greco, F.1    Vicent, M.J.2
  • 7
    • 29144516614 scopus 로고    scopus 로고
    • Combination therapy with doxazosin and finasteride for benign prostatic hyperplasia in patients with lower urinary tract symptoms and a baseline total prostate volume of 25 Ml or greater
    • DOI 10.1016/S0022-5347(05)00041-8, PII S0022534705000418
    • S.A. Kaplan, J.D. Mcconnell, C.G. Roehrborn, A.G. Meehan, M.W. Lee, and W.R. Noble Combination therapy with doxazosin and finasteride for benign prostatic hyperplasia in patients with lower urinary tract symptoms and a baseline total prostate volume of 25 ml or greater The Journal of Urology 175 2006 217 220 (Pubitemid 41797144)
    • (2006) Journal of Urology , vol.175 , Issue.1 , pp. 217-220
    • Kaplan, S.A.1    McConnell, J.D.2    Roehrborn, C.G.3    Meehan, A.G.4    Lee, M.W.5    Noble, W.R.6    Kusek, J.W.7    Nyberg Jr., L.M.8
  • 8
    • 12344281713 scopus 로고    scopus 로고
    • Observations in simultaneous microencapsulation of 5-fluorouracil and leucovorin for combined pH-dependent release
    • DOI 10.1016/j.ejpb.2004.09.005, PII S0939641104002528
    • A. Lamprecht, H. Yamamoto, H. Takeuchi, and Y. Kawashima Observations in simultaneous microencapsulation of 5-fluorouracil and leucovorin for combined pH-dependent release European Journal of Pharmaceutics and Biopharmaceutics 59 2005 367 371 (Pubitemid 40127594)
    • (2005) European Journal of Pharmaceutics and Biopharmaceutics , vol.59 , Issue.2 , pp. 367-371
    • Lamprecht, A.1    Yamamoto, H.2    Takeuchi, H.3    Kawashima, Y.4
  • 9
    • 79953311845 scopus 로고    scopus 로고
    • Synthesis and characterization of folate conjugated chitosan and cellular uptake of its nanoparticles in HT-29 cells
    • P.W. Li, Y.C. Wang, F.B. Zeng, L.J. Chen, Z. Peng, and L.X. Kong Synthesis and characterization of folate conjugated chitosan and cellular uptake of its nanoparticles in HT-29 cells Carbohydrate Research 346 2011 801 806
    • (2011) Carbohydrate Research , vol.346 , pp. 801-806
    • Li, P.W.1    Wang, Y.C.2    Zeng, F.B.3    Chen, L.J.4    Peng, Z.5    Kong, L.X.6
  • 10
    • 33845479268 scopus 로고    scopus 로고
    • Preparation and characterization of N-(2-carboxybenzyl)chitosan as a potential pH-sensitive hydrogel for drug delivery
    • DOI 10.1016/j.carres.2006.11.002, PII S0008621506005015
    • Y.W. Lin, Q. Chen, and H.B. Luo Preparation and characterization of N-(2-carboxybenzyl)chitosan as a potential pH-sensitive hydrogel for drug delivery Carbohydrate Research 342 2007 87 95 (Pubitemid 44917937)
    • (2007) Carbohydrate Research , vol.342 , Issue.1 , pp. 87-95
    • Lin, Y.1    Chen, Q.2    Luo, H.3
  • 11
    • 0035941002 scopus 로고    scopus 로고
    • Adsorption of indomethacin onto chemically modified chitosan beads
    • F.L. Mi, S.S. Shyu, C.T. Chen, and J.Y. Lai Adsorption of indomethacin onto chemically modified chitosan beads Polymer 43 2002 757 765
    • (2002) Polymer , vol.43 , pp. 757-765
    • Mi, F.L.1    Shyu, S.S.2    Chen, C.T.3    Lai, J.Y.4
  • 12
    • 0031817770 scopus 로고    scopus 로고
    • The role of combination therapy in the treatment of hypertension
    • PII S0895706198000600
    • M. Moser, and H.R. Black The role of combination therapy in the treatment of hypertension American Journal of Hypertension 11 1998 73S 78S (Pubitemid 28318285)
    • (1998) American Journal of Hypertension , vol.11 , Issue.6 SUPPL.
    • Moser, M.1    Black, H.R.2
  • 13
    • 36448962396 scopus 로고    scopus 로고
    • Combination therapy for treatment of osteoporosis: A review
    • DOI 10.1016/j.ajog.2007.07.022, PII S0002937807009015
    • J.V. Pinkerton, and A.C. Dalkin Combination therapy for treatment of osteoporosis: A review American Journal of Obstetrics and Gynecology 197 2007 559 565 (Pubitemid 350166248)
    • (2007) American Journal of Obstetrics and Gynecology , vol.197 , Issue.6 , pp. 559-565
    • Pinkerton, J.V.1    Dalkin, A.C.2
  • 14
    • 0009365216 scopus 로고    scopus 로고
    • A review of chitin and chitosan applications
    • PII S1381514800000389
    • M.N.V. Ravi Kumar A review of chitin and chitosan applications Reactive and Functional Polymers 46 2000 1 27 (Pubitemid 33763425)
    • (2000) Reactive and Functional Polymers , vol.46 , Issue.1 , pp. 1-27
    • Ravi Kumar, M.N.V.1
  • 16
    • 33750055745 scopus 로고    scopus 로고
    • Surface modification of chitosan for selective surface-protein interaction
    • DOI 10.1016/j.carbpol.2006.03.022, PII S0144861706001548
    • A. Subramanian, A.V. Rau, and H. Kaligotla Surface modification of chitosan for selective surface-protein interaction Carbohydrate Polymers 66 2006 321 332 (Pubitemid 44585064)
    • (2006) Carbohydrate Polymers , vol.66 , Issue.3 , pp. 321-332
    • Subramanian, A.1    Rau, A.V.2    Kaligotla, H.3
  • 17
    • 34250195000 scopus 로고    scopus 로고
    • Preparation of nanoparticles composed of chitosan and its derivatives as delivery systems for macromolecules
    • DOI 10.1002/app.26038
    • Y. Sun, and A.J. Wan Preparation of nanoparticles composed of chitosan and its derivatives as delivery systems for macromolecules Journal of Applied Polymer Science 105 2007 552 561 (Pubitemid 46896620)
    • (2007) Journal of Applied Polymer Science , vol.105 , Issue.2 , pp. 552-561
    • Sun, Y.1    Wan, A.2
  • 18
    • 39449107290 scopus 로고    scopus 로고
    • Chitosan nanoparticles: A promising system for drug delivery
    • W. Tiyaboonchai Chitosan nanoparticles: A promising system for drug delivery Naresuan University Journal 11 2003 51 66
    • (2003) Naresuan University Journal , vol.11 , pp. 51-66
    • Tiyaboonchai, W.1
  • 19
    • 57749182923 scopus 로고    scopus 로고
    • Preparation of aspirin and probucol in combination loaded chitosan nanoparticles and in vitro release study
    • A.J. Wan, Y. Sun, L.P. Gao, and H.L. Li Preparation of aspirin and probucol in combination loaded chitosan nanoparticles and in vitro release study Carbohydrate Polymers 75 2009 566 574
    • (2009) Carbohydrate Polymers , vol.75 , pp. 566-574
    • Wan, A.J.1    Sun, Y.2    Gao, L.P.3    Li, H.L.4
  • 20
    • 67349172117 scopus 로고    scopus 로고
    • The effect of the molecular weight of chitosan nanoparticles and its application on drug delivery
    • H.-C. Yang, and M.-H. Hon The effect of the molecular weight of chitosan nanoparticles and its application on drug delivery Microchemical Journal 92 2009 87 91
    • (2009) Microchemical Journal , vol.92 , pp. 87-91
    • Yang, H.-C.1    Hon, M.-H.2
  • 21
    • 35348895676 scopus 로고    scopus 로고
    • Nanoparticles based on the complex of chitosan and polyaspartic acid sodium salt: Preparation, characterization and the use for 5-fluorouracil delivery
    • DOI 10.1016/j.ejpb.2007.04.007, PII S0939641107001464
    • Y.L. Zheng, W. Yang, C.C. Wang, J.H. Hu, S.K. Fu, and L. Dong Nanoparticles based on the complex of chitosan and polyaspartic acid sodium salt: Preparation, characterization and the use for 5-fluorouracil delivery European Journal of Pharmaceutics and Biopharmaceutics 67 2007 621 631 (Pubitemid 47576611)
    • (2007) European Journal of Pharmaceutics and Biopharmaceutics , vol.67 , Issue.3 , pp. 621-631
    • Zheng, Y.1    Yang, W.2    Wang, C.3    Hu, J.4    Fu, S.5    Dong, L.6    Wu, L.7    Shen, X.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.