Physical state and dissolution of ibuprofen formulated by co-spray drying with mesoporous silica: Effect of pore and particle size

International Journal of Pharmaceutics

Volumn 410, Issue 1-2, 2011, Pages 188-195

  Shen, Shou Cang ^a   Ng, Wai Kiong ^a   Chia, Leonard ^a   Hu, Jun ^a   Tan, Reginald B H ^a,b  

^a INSTITUTE OF CHEMICAL AND ENGINEERING SCIENCES   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Amorphous; Co spray drying; Dissolution; Mesoporous silica; Nanocrystals

Indexed keywords

IBUPROFEN; MCM 41; NANOCRYSTAL; SILICON DIOXIDE;

ARTICLE; CRYSTAL STRUCTURE; DRUG DIFFUSION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STRUCTURE; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SPRAY DRYING;

CRYSTALLIZATION; DIFFUSION; IBUPROFEN; KINETICS; NANOPARTICLES; PARTICLE SIZE; POROSITY; SILICON DIOXIDE; SOLUBILITY;

EID: 79955636907     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.03.018     Document Type: Article

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