Helicobacter pylori isolates from proximal and distal stomach of patients never treated and already treated show genetic variability and discordant antibiotic resistance

European Journal of Gastroenterology and Hepatology

Volumn 23, Issue 6, 2011, Pages 467-472

  Marzio, Leonardo ^a   Cellini, Lugina ^b   Amitrano, Maria ^a   Grande, Rossella ^b   Serio, Mariaelena ^a   Cappello, Giorgio ^a   Grossi, Laurino ^a  

^a Ospedale Civile di Pescara   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

Antibiotic resistance; antrum; culture; DNA fingerprintings; fundus; Helicobactor pylori; mixed infection; susceptibility test

Indexed keywords

AMOXICILLIN; BACTERIAL DNA; CLARITHROMYCIN; LEVOFLOXACIN; MOXIFLOXACIN; RIFABUTIN; TINIDAZOLE;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; CONTROLLED STUDY; DNA FINGERPRINTING; FEMALE; GENETIC VARIABILITY; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; NONHUMAN; PRIORITY JOURNAL; STOMACH; STOMACH ANTRUM; STOMACH FUNDUS;

ADULT; AGED; ANTI-BACTERIAL AGENTS; BIOPSY; BREATH TESTS; CHI-SQUARE DISTRIBUTION; DNA FINGERPRINTING; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; FEMALE; GASTRIC FUNDUS; GASTROSCOPY; GENETIC VARIATION; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INCIDENCE; ITALY; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PHENOTYPE; PYLORIC ANTRUM; TREATMENT FAILURE; YOUNG ADULT;

EID: 79955635221     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MEG.0b013e328345d40f     Document Type: Article

References (23)

1. Zhang C, Yamada N,Wu YL,Wen M, Matsuhisa T, Matsukura N. Comparison of Helicobacter pylori infection and gastric mucosal histological features of gastric ulcer patients with chronic gastritis patients. World J Gastroenterol 2005; 11:976-981 (Pubitemid 40347748)
2. Brenner H, Weyermann M, Rothenbacher D. Clustering of Helicobacter pylori infection in couples: Differences between high- and low-prevalence population groups. Ann Epidemiol 2006; 16:516-520 (Pubitemid 43928631)
3. Sheu SM, Sheu BS, Lu CC, Yang HB, Wu JJ. Mixed infections of Helicobacter pylori: Tissue tropism and histological significance. Clin Microbiol Infect 2009; 15:253-259
4. Yakoob J, Fan XG, Hu GL, Yang HX, Liu L, Liu SH, et al. Polycolonization of Helicobacter pylori among Chinese subjects. Clin Microbiol Infect 2001; 7:187-192 (Pubitemid 34966116)
5. Ziemniak W. Efficacy of Helicobacter pylori eradication taking into account its resistance to antibiotics. J Physiol Pharmacol 2006; 57 (Suppl 3):123-141 (Pubitemid 44641541)
6. Egan BJ, Katicic M, O'Connor HJ, O'Morain CA. Treatment of Helicobacter pylori. Helicobacter 2007; 12 (Suppl 1):31-37 (Pubitemid 47312378)
7. Romano M, Marmo R, Cuomo A, De Simone T, Mucherino C, Iovene MR, et al. Pretreatment antimicrobial susceptibility testing is cost saving in the eradication of Helicobacter pylori. Clin Gastroenterol Hepatol 2003; 1:273-278 (Pubitemid 37254454)
8. Clinical Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. 16th Informational Supplement M100-S16. Wayne, PA: CLSI; 2006
9. Cellini L, Grande R, Di Campli E, Di Bartolomeo S, Capodicasa S, Marzio L. Analysis of genetic variability, antimicrobial susceptibility and virulence markers in Helicobacter pylori identified in Central Italy. Scand J Gastroenterol 2006; 41:280-287
10. Gisbert JP, Abraira V. Accuracy of Helicobacter pylori diagnostic tests in patients with bleeding peptic ulcer: A systematic review and meta-analysis. Am J Gastroenterol 2006; 101:848-863
11. Van Amsterdam K, Van Vliet AH, Kusters JG, Van der Ende A. Of microbe and man: Determinants of Helicobacter pylori-related diseases. FEMS Microbiol Rev 2006; 30:131-156
12. Caristo E, Parola A, Rapa A, Vivenza D, Raselli B, Dondi E, et al. Clarithromycin resistance of Helicobacter pylori strains isolated from children' gastric antrum and fundus as assessed by fluorescent in-situ hybridization and culture on four-sector agar plates. Helicobacter 2008; 13:557-563
13. Suerbaum S, Josenhans C. Helicobacter pylori evolution and phenotypic diversification in a changing host. Nat Rev Microbiol 2007; 5:441-452 (Pubitemid 46780081)
14. Amieva MR, El-Omar EM. Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology 2008; 134:306-323 (Pubitemid 350309334)
15. Marzio L, Coraggio D, Capodicasa S, Grossi L, Cappello G. Role of the preliminary susceptibility testing for initial and after failed therapy of Helicobacter pylori infection with levofloxacin, amoxicillin, and esomeprazole. Helicobacter 2006; 11:237-242 (Pubitemid 44051349)
16. Kalach N, Serhal L, Asmar E, Campeotto F, Bergeret M, Dehecq E, et al. Helicobacter pylori primary resistant strains over 11 years in French children. Diagn Microbiol Infect Dis 2007; 59:217-222 (Pubitemid 47484134)
17. Glocker E, Bogdan C, Kist M. Characterization of rifampicin-resistant clinical Helicobacter pylori isolates from Germany. J Antimicrob Chemother 2007; 59:874-879 (Pubitemid 47073357)
18. Kim JM, Kim JS, Kim N, Jung HC, Song IS. Distribution of fluoroquinolone MICs in Helicobacter pylori strains from Korean patients. J Antimicrob Chemother 2005; 56:965-967 (Pubitemid 41631929)
19. Gisbert JP, Fernà ndez-Bermejo M, Molina-Infante J, PO ̃ rez-Gallardo B, Prieto-Bermejo AB, Mateos-RodrÚ guez JM, et al. First-line triple therapy with levofloxacin for Helicobacter pylori eradication. Aliment Pharmacol Ther 2007; 26:495-500
20. Bogaerts P, Berhin C, Nizet H, Glupczynski Y. Prevalence and mechanisms of resistance to fluoroquinolones in Helicobacter pylori strains from patients living in Belgium. Helicobacter 2006; 11:441-445 (Pubitemid 44352615)
21. Malfertheiner P, Megraud F, O'Morain C, Bazzoli F, El-Omar E, Graham D, et al. Current concepts in the management of Helicobacter pylori infection: The Maastricht III Consensus Report. Gut 2007; 56:772-781 (Pubitemid 46854190)
22. MO ̃ graud F, Lehours P. Helicobacter pylori detection and antimicrobial susceptibility testing. Clin Microbiol Rev 2007; 20:280-322 (Pubitemid 46709306)
23. Kim JJ, Kim JG, Kwon DH. Mixed-infection of antibiotic susceptible and resistant Helicobacter pylori isolates in a single patient and underestimation of antimicrobial susceptibility testing. Helicobacter 2003; 8:202-206. (Pubitemid 36712404)