Optimal oxygenation during and after cardiopulmonary resuscitation

Current Opinion in Critical Care

Volumn 17, Issue 3, 2011, Pages 236-240

  Neumar, Robert W ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

cardiac arrest; cardiopulmonary resuscitation; hyperoxemia; oxygen, post cardiac arrest syndrome

Indexed keywords

ARTERIAL OXYGEN SATURATION; HEART ARREST; HEART MUSCLE OXYGEN CONSUMPTION; HUMAN; HYPEROXIA; INTENSIVE CARE UNIT; MORTALITY; NONHUMAN; OXYGEN CONCENTRATION; OXYGEN THERAPY; OXYGEN TOXICITY; RESUSCITATION; RETURN OF SPONTANEOUS CIRCULATION; REVIEW;

ANIMALS; ANOXIA; CARDIOPULMONARY RESUSCITATION; EVIDENCE-BASED MEDICINE; HEART ARREST; HUMANS; OXYGEN INHALATION THERAPY;

EID: 79955617671     PISSN: 10705295     EISSN: 15317072     Source Type: Journal    
DOI: 10.1097/MCC.0b013e3283454c8c     Document Type: Review

References (20)

1. Lambert AJ, Brand MD. Reactive oxygen species production by mitochondria. Methods Mol Biol 2009; 554:165-181.
2. Leto TL, Morand S, Hurt D, Ueyama T. Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases. Antioxid Redox Signal 2009; 11:2607-2619.
3. Rossi S, Longhi L, Balestreri M, et al. Brain oxygen tension during hyperoxia in a swine model of cerebral ischaemia. Acta Neurochir Suppl 2000; 76:243-245.
4. Cavus E, Bein B, Dörges V, et al. Brain tissue oxygen pressure and cerebral metabolism in an animal model of cardiac arrest and cardiopulmonary resuscitation. Resuscitation 2006; 71:97-106. (Pubitemid 44404095)
5. Imberti R, Bellinzona G, Riccardi F, et al. Cerebral perfusion pressure and cerebral tissue oxygen tension in a patient during cardiopulmonary resuscitation. Intensive Care Med 2003; 29:1016-1019. (Pubitemid 36783179)
6. Marsala J, Marsala M, Vanicky I, et al. Post cardiac arrest hyperoxic resuscitation enhances neuronal vulnerability of the respiratory rhythm generator and some brainstem and spinal cord neuronal pools in the dog. Neurosci Lett 1992; 146:121-124.
7. Zwemer CF, Whitesall SE, D'Alecy LG. Cardiopulmonary-cerebral resuscitation with 100% oxygen exacerbates neurological dysfunction following nine minutes of normothermic cardiac arrest in dogs. Resuscitation 1994; 27: 159-170. (Pubitemid 24100649)
8. Liu Y, Rosenthal RE, Haywood Y, et al. Normoxic ventilation after cardiac arrest reduces oxidation of brain lipids and improves neurological outcome. Stroke 1998; 29:1679-1686. (Pubitemid 28365593)
9. Vereczki V, Martin E, Rosenthal RE, et al. Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic dysfunction, and neuronal death. J Cereb Blood Flow Metab 2006; 26:821-823.
10. Balan IS, Fiskum G, Hazelton J, et al. Oximetry-guided reoxygenation improves neurological outcome after experimental cardiac arrest. Stroke 2006; 37: 3008-3013. (Pubitemid 44900823)
11. Brücken A, Kaab AB, Kottmann K, et al. Reducing the duration of 100% oxygen ventilation in the early reperfusion period after cardiopulmonary resuscitation decreases striatal brain damage. Resuscitation 2010; 81: 1698-1703.
12. Lipinski CA, Hicks SD, Callaway CW. Normoxic ventilation during resuscitation and outcome from asphyxial cardiac arrest in rats. Resuscitation 1999; 42:221-229.
13. Yeh ST, Cawley RJ, Aune SE, Angelos MG. Oxygen requirement during cardiopulmonary resuscitation (CPR) to effect return of spontaneous circulation. Resuscitation 2009; 80:951-955.
14. Walson KH, Tang M, Glumac A, et al. Normoxic versus hyperoxic resuscitation in pediatric asphyxial cardiac arrest: effects on oxidative stress. Crit Care Med 2010 [Epub ahead of print].
15. Kuisma M, Boyd J, Voipio V, et al. Comparison of 30 and the 100% inspired oxygen concentrations during early postresuscitation period: a randomised controlled pilot study. Resuscitation 2006; 69:199-206.
16. Kilgannon JH, Jones AE, Shapiro NI, et al. Emergency Medicine Shock Research Network (EMShockNet) Investigators. Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality. JAMA 2010; 303:2165-2171.
17. Farquhar H, Weatherall M, Wijesinghe M, et al. Systematic review of studies of the effect of hyperoxia on coronary blood flow. Am Heart J 2009; 158:371-377.
18. Morrison LJ, Deakin CD, Morley PT, et al., Advanced Life Support Chapter Collaborators. Part 8: advanced life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation 2010; 122 (Suppl 2): S345-S421.
19. Peberdy MA, Callaway CW, Neumar RW, et al. Part 9: Post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2010; 122 (Suppl 3):S768-S786.
20. Deakin CD, Nolan JP, Soar J, et al. European Resuscitation Council Guidelines for Resuscitation 2010 Section 4. Adult advanced life support. Resuscitation 2010; 81:1305-1352.