Assessment of potential pharmacokinetic interactions of ezetimibe/simvastatin and extended-release niacin tablets in healthy subjects

European Journal of Clinical Pharmacology

Volumn 67, Issue 5, 2011, Pages 483-492

  Kosoglou, Teddy ^a   Zhu, Yali ^a   Statkevich, Paul ^a   Triantafyllou, Ilias ^a   Taggart, William ^a   Xuan, Fengjuan ^a   Kim, Kenneth T ^b   Cutler, David L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b West Coast Clinical Trials LLC   (United States)

Author keywords

Extended release niacin; Ezetimibe; Pharmacokinetics; Simvastatin

Indexed keywords

DRUG METABOLITE; EZETIMIBE PLUS SIMVASTATIN; NICOTINIC ACID;

ADULT; ARTICLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EXPOSURE; DRUG RELEASE; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; HEADACHE; HOT FLUSH; HUMAN; HUMAN EXPERIMENT; MALE; MAXIMUM PLASMA CONCENTRATION; MYALGIA; NORMAL HUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINGLE BLIND PROCEDURE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADULT; ANTICHOLESTEREMIC AGENTS; AZETIDINES; CROSS-OVER STUDIES; DELAYED-ACTION PREPARATIONS; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; HYPOLIPIDEMIC AGENTS; LIPIDS; MALE; NIACIN; NICOTINIC ACIDS; SIMVASTATIN; TABLETS;

EID: 79955617145     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-010-0955-6     Document Type: Article

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