Patterns of failure and treatment-related toxicity in advanced cervical cancer patients treated using extended field radiotherapy with curative intent

International Journal of Radiation Oncology Biology Physics

Volumn 80, Issue 2, 2011, Pages 422-428

  Rajasooriyar, Chrishanthi ^a   Van Dyk, Sylvia ^b   Bernshaw, David ^b   Kondalsamy Chennakesavan, Srinivas ^c,d   Barkati, Maroie ^b   Narayan, Kailash ^b  

^a Teaching Hospital   (Sri Lanka)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

^c ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Chemoradiation; Extended field radiotherapy; Toxicity; Treatment outcome; Uterine cervical cancer

Indexed keywords

BONE MARROW; BRACHYTHERAPY; CERVICAL CANCERS; CHEMORADIATION; CONCURRENT CHEMOTHERAPY; CONFIDENCE INTERVAL; CURATIVE INTENT; DISEASE-FREE SURVIVAL; EXTENDED FIELD RADIOTHERAPY; GASTROINTESTINAL TOXICITIES; LYMPH NODE; METASTATIC DISEASE; OVERALL SURVIVAL; PATTERNS OF FAILURE; SALVAGE TREATMENT; TOTAL DOSE; TREATMENT FAILURE; TREATMENT OUTCOME; UTERINE CERVICAL CANCER;

CHEMOTHERAPY; DISEASES; ONCOLOGY; PATIENT MONITORING; TOXICITY;

RADIOTHERAPY;

CISPLATIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BRACHYTHERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL ARTICLE; DISEASE FREE SURVIVAL; FEMALE; HUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; RADIATION FIELD; RADIATION INJURY; RETROSPECTIVE STUDY; TREATMENT FAILURE; UTERINE CERVIX CANCER;

ADENOCARCINOMA; ADULT; AGED; BONE MARROW; BRACHYTHERAPY; CARCINOMA, SQUAMOUS CELL; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; GASTROINTESTINAL TRACT; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; RADIATION INJURIES; RADIOTHERAPY DOSAGE; RETROSPECTIVE STUDIES; SALVAGE THERAPY; UTERINE CERVICAL NEOPLASMS;

EID: 79955605768     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.02.026     Document Type: Article

References (18)

1. Y.S. Kim, J.H. Kim, and S.D. Ahn High-dose extended-field irradiation and high-dose-rate brachytherapy with concurrent chemotherapy for cervical cancer with positive para-aortic lymph nodes Int J Radiat Oncol Biol Phys 74 5 2009 1522 1528
2. I.L. Atahan, C. Onal, E. Ozyar, F. Yiliz, U. Selek, and F. Kose Long-term outcome and prognostic factors in patients with cervical carcinoma: A retrospective study Int J Gynecol Cancer 17 4 2007 833 842 (Pubitemid 47063341)
3. P.W. Grigsby, B.A. Siegel, and F. Dehdashti Lymph node staging by positron emission tomography in patients with carcinoma of the cervix J Clin Oncol 19 17 2001 3745 3749 (Pubitemid 32844787)
4. E. Podczaski, J.A. Stryker, and P. Kaminski Extended-field radiation therapy for carcinoma of the cervix Cancer 66 2 1990 251 258 (Pubitemid 20205904)
5. J.A. Stryker, and R. Mortel Survival following extended field irradiation in carcinoma of cervix metastatic to para-aortic lymph nodes Gynecol Oncol 79 3 2000 399 405
6. J.L. Walker, A. Morrison, P. DiSilvestro, and G.V. Von A phase I/II study of extended field radiation therapy with concomitant paclitaxel and cisplatin chemotherapy in patients with cervical carcinoma metastatic to the para-aortic lymph nodes: A Gynecologic Oncology Group study Gynecol Oncol 112 1 2009 78 84
7. J.L. Benedet, H. Bender, H. Jones III, H.Y. Ngan, and S. Pecorelli FIGOstaging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology Int J Gynaecol Obstet 70 2000 209 262
8. J.D. Cox, J. Stetz, and T.F. Pajak Toxicity criteria of the radiation therapy oncology group(rtog) and the european organization for research and treatment of cancer (eortc) Int J Radiation Oncology Biol Phys 3 5 1995 1341 1346
9. K. Narayan, D.S. van, D. Bernshaw, C. Rajasooriyar, and S. Kondalsamy-Chennakesavan Comparative study of LDR (Manchester system) and HDR image-guided conformal brachytherapy of cervical cancer: Patterns of failure, late complications, and survival Int J Radiat Oncol Biol Phys 74 5 2009 1529 1535
10. M.A. Varia, B.N. Bundy, and G. Deppe Cervical carcinoma metastatic to para-aortic nodes: extended field radiation therapy with concomitant 5-fluorouracil and cisplatin chemotherapy: A Gynecologic Oncology Group study Int J Radiat Oncol Biol Phys 42 5 1998 1015 1023 (Pubitemid 29004143)
11. P.W. Grigsby, C.A. Perez, K.S. Chao, T. Herzog, D.G. Mutch, and J. Rader Radiation therapy for carcinoma of the cervix with biopsy-proven positive para-aortic lymph nodes Int J Radiat Oncol Biol Phys 49 3 2001 733 738 (Pubitemid 32112198)
12. P. Lepanto, P. Littman, J. Mikuta, L. Davis, and J. Celebre Treatment of para-aortic nodes in carcinoma of the cervix Cancer 35 6 1975 1510 1513
13. S. Mutic, R.S. Malyapa, and P.W. Grigsby PET-guided IMRT for cervical carcinoma with positive para-aortic lymph nodes-a dose-escalation treatment planning study Int J Radiat Oncol Biol Phys 55 1 2003 28 35 (Pubitemid 36020341)
14. R.J. Hale, C.H. Buckley, H. Fox, F.L. Wilcox, V.R. Tintdall, and J.P. Logue The morphology and distribution of lymph node metastases in stage 1B/11A cervical carcinoma: Relationship to prognosis Int J Gynecol Cancer 1 5 1991 233 237
15. E. Leblanc, F. Narducci, and M. Frumovitz Therapeutic value of pretherapeutic extraperitoneal laparoscopic staging of locally advanced cervical carcinoma Gynecol Oncol 105 2 2007 304 311 (Pubitemid 46590320)
16. J. Small, K. Winter, and C. Levenback Extended-field irradiation and intracavitary brachytherapy combined with cisplatin chemotherapy for cervical cancer with positive para-aortic or high common iliac lymph nodes: Results of ARM 1 of RTOG 0116 Int J Radiat Oncol Biol Phys 68 4 2007 1081 1087 (Pubitemid 47048563)
17. P.W. Grigsby, K. Heydon, D.G. Mutch, R.Y. Kim, and P. Eifel Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes Int J Radiat Oncol Biol Phys 51 4 2001 982 987 (Pubitemid 33026428)
18. B.M. Sood, P.F. Timmins, and G.R. Gorla Concomitant cisplatin and extended field radiation therapy in patients with cervical and endometrial cancer Int J Gynecol Cancer 12 5 2002 459 464