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Volumn 91, Issue 10, 2011, Pages 1159-1165

Prospective study of everolimus with calcineurin inhibitor-free immunosuppression in maintenance heart transplant patients: Results at 2 years

Author keywords

Certican; CNI free; Conversion; Everolimus; Heart transplantation; Renal function

Indexed keywords

CALCINEURIN INHIBITOR; CYCLOSPORIN A; EVEROLIMUS; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; STEROID;

EID: 79955601688     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31821774bd     Document Type: Article
Times cited : (19)

References (28)
  • 1
    • 1942484480 scopus 로고    scopus 로고
    • Calcineurin inhibitors in heart transplantation
    • Keogh A. Calcineurin inhibitors in heart transplantation. J Heart Lung Transplant 2004; 23(suppl 5): S202.
    • (2004) J Heart Lung Transplant , vol.23 , Issue.SUPPL. 5
    • Keogh, A.1
  • 3
    • 11144250154 scopus 로고    scopus 로고
    • Drug therapy in the heart transplant recipient: Part II: Immunosuppressive drugs
    • Lindenfeld J, Miller GG, Shakar SF, et al. Drug therapy in the heart transplant recipient: Part II: Immunosuppressive drugs. Circulation 2004; 110: 3858.
    • (2004) Circulation , vol.110 , pp. 3858
    • Lindenfeld, J.1    Miller, G.G.2    Shakar, S.F.3
  • 4
    • 2342518773 scopus 로고    scopus 로고
    • Everolimus
    • discussion 873
    • Chapman TM, Perry CM. Everolimus. Drugs 2004; 64: 861; discussion 873.
    • (2004) Drugs , vol.64 , pp. 861
    • Chapman, T.M.1    Perry, C.M.2
  • 5
    • 19244366021 scopus 로고    scopus 로고
    • Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients
    • Eisen HJ, Tuzcu EM, Dorent R, et al. Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients. N Engl J Med 2003; 349: 847.
    • (2003) N Engl J Med , vol.349 , pp. 847
    • Eisen, H.J.1    Tuzcu, E.M.2    Dorent, R.3
  • 6
    • 58049202927 scopus 로고    scopus 로고
    • Outcomes following de novo CNI-free immunosuppression after heart transplantation: A singlecenter experience
    • Leet AS, Bergin PJ, Richardson M, et al. Outcomes following de novo CNI-free immunosuppression after heart transplantation: A singlecenter experience. Am J Transplant 2009; 9: 140.
    • (2009) Am J Transplant , vol.9 , pp. 140
    • Leet, A.S.1    Bergin, P.J.2    Richardson, M.3
  • 7
    • 20244388105 scopus 로고    scopus 로고
    • A randomized activecontrolled trial of mycophenolate mofetil in heart transplant recipients
    • Mycophenolate Mofetil Investigators
    • Kobashigawa J, Miller L, Renlund D, et al. A randomized activecontrolled trial of mycophenolate mofetil in heart transplant recipients. Mycophenolate Mofetil Investigators. Transplantation 1998; 66: 507.
    • (1998) Transplantation , vol.66 , pp. 507
    • Kobashigawa, J.1    Miller, L.2    Renlund, D.3
  • 8
    • 21244454092 scopus 로고    scopus 로고
    • Initial experience with sirolimus and mycophenolate mofetil for renal rescue from cyclosporine nephrotoxicity after heart transplantation
    • Lyster H, Panicker G, Leaver N, et al. Initial experience with sirolimus and mycophenolate mofetil for renal rescue from cyclosporine nephrotoxicity after heart transplantation. Transplant Proc 2004; 36: 3167.
    • (2004) Transplant Proc , vol.36 , pp. 3167
    • Lyster, H.1    Panicker, G.2    Leaver, N.3
  • 9
    • 2642568316 scopus 로고    scopus 로고
    • Sirolimus and mycophenolate mofetil as calcineurin inhibitor-free immunosuppression in a cardiac transplant patient with chronic renal failure
    • Groetzner J, Kaczmarek I, Meiser B, et al. Sirolimus and mycophenolate mofetil as calcineurin inhibitor-free immunosuppression in a cardiac transplant patient with chronic renal failure. J Heart Lung Transplant 2004; 23: 770.
    • (2004) J Heart Lung Transplant , vol.23 , pp. 770
    • Groetzner, J.1    Kaczmarek, I.2    Meiser, B.3
  • 10
    • 15044347566 scopus 로고    scopus 로고
    • Prevention of cardiac allograft vasculopathy with Certican (everolimus): The Stanford University experience within the Certican Phase III clinical trial
    • Valantine H. Prevention of cardiac allograft vasculopathy with Certican (everolimus): The Stanford University experience within the Certican Phase III clinical trial. J Heart Lung Transplant 2005; 24(suppl 4): S191.
    • (2005) J Heart Lung Transplant , vol.24 , Issue.SUPPL. 4
    • Valantine, H.1
  • 11
    • 15044351065 scopus 로고    scopus 로고
    • Clinical experience with Certican (everolimus) in de novo heart transplant patients at the Deutsches Herzzentrum Berlin
    • Lehmkuhl H, Hetzer R. Clinical experience with Certican (everolimus) in de novo heart transplant patients at the Deutsches Herzzentrum Berlin. J Heart Lung Transplant 2005; 24(suppl 4): S201.
    • (2005) J Heart Lung Transplant , vol.24 , Issue.SUPPL. 4
    • Lehmkuhl, H.1    Hetzer, R.2
  • 12
    • 38949126946 scopus 로고    scopus 로고
    • Cyclosporine reduction in the presence of everolimus: 3-month data from a Canadian pilot study of maintenance cardiac allograft recipients
    • Ross H, Flugfelder P, Haddad H, et al. Cyclosporine reduction in the presence of everolimus: 3-month data from a Canadian pilot study of maintenance cardiac allograft recipients. J Heart Lung Transplant 2008; 27: 197.
    • (2008) J Heart Lung Transplant , vol.27 , pp. 197
    • Ross, H.1    Flugfelder, P.2    Haddad, H.3
  • 13
    • 15044345672 scopus 로고    scopus 로고
    • Clinical experience with Certican (everolimus) in maintenance heart transplant patients at the Medical University of Vienna
    • Zuckermann A. Clinical experience with Certican (everolimus) in maintenance heart transplant patients at the Medical University of Vienna. J Heart Lung Transplant 2005; 24(suppl 4): S206.
    • (2005) J Heart Lung Transplant , vol.24 , Issue.SUPPL. 4
    • Zuckermann, A.1
  • 14
    • 33847375217 scopus 로고    scopus 로고
    • Calcineurin inhibitor-free immunosuppression using everolimus (Certican) in maintenance heart transplant recipients: 6 months' follow-up
    • Rothenburger M, Teerling E, Bruch C, et al. Calcineurin inhibitor-free immunosuppression using everolimus (Certican) in maintenance heart transplant recipients: 6 months' follow-up. J Heart Lung Transplant 2007; 26: 250.
    • (2007) J Heart Lung Transplant , vol.26 , pp. 250
    • Rothenburger, M.1    Teerling, E.2    Bruch, C.3
  • 15
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16: 31.
    • (1976) Nephron , vol.16 , pp. 31
    • Cockcroft, D.W.1    Gault, M.H.2
  • 16
    • 65249134974 scopus 로고    scopus 로고
    • Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: CONCEPT study
    • Lebranchu Y, Thierry A, Toupance O, et al. Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: CONCEPT study. Am J Transplant 2009; 9: 1115.
    • (2009) Am J Transplant , vol.9 , pp. 1115
    • Lebranchu, Y.1    Thierry, A.2    Toupance, O.3
  • 17
    • 74549123609 scopus 로고    scopus 로고
    • Mycophenolate mofetil/sirolimus maintenance therapy after calcineurin inhibitor withdrawal in renal transplant recipients: 2-year outcomes of the Spare-the-Nephron (STN) trial
    • Weir M, Mulgaonkar S, Pearson T, et al. Mycophenolate mofetil/sirolimus maintenance therapy after calcineurin inhibitor withdrawal in renal transplant recipients: 2-year outcomes of the Spare-the-Nephron (STN) trial. Am J Transplant 2009; 9: 200 (abstract 33).
    • (2009) Am J Transplant , vol.9 , pp. 200
    • Weir, M.1    Mulgaonkar, S.2    Pearson, T.3
  • 18
    • 77957580949 scopus 로고    scopus 로고
    • Analysis of renal function in everolimus/enteric-coated mycophenolate sodium treated de novo renal transplant recipients after calcineurin inhibitor withdrawal: The Zeus Study
    • Budde K, Becker T, Sommerer C, et al. Analysis of renal function in everolimus/enteric-coated mycophenolate sodium treated de novo renal transplant recipients after calcineurin inhibitor withdrawal: The Zeus Study. Am J Transplant 2009; 9: 259 (abstract 237).
    • (2009) Am J Transplant , vol.9 , pp. 259
    • Budde, K.1    Becker, T.2    Sommerer, C.3
  • 19
    • 33750011166 scopus 로고    scopus 로고
    • Cyclosporine withdrawal improves renal function in heart transplant patients on reduced-dose cyclosporine therapy
    • Gleissner CA, Doesch A, Ehlermann P, et al. Cyclosporine withdrawal improves renal function in heart transplant patients on reduced-dose cyclosporine therapy. Am J Transplant 2006; 6: 2750.
    • (2006) Am J Transplant , vol.6 , pp. 2750
    • Gleissner, C.A.1    Doesch, A.2    Ehlermann, P.3
  • 20
    • 59649126728 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial
    • Schena FP, Pascoe MD, Alberu J, et al. Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. Transplantation 2009; 87: 233.
    • (2009) Transplantation , vol.87 , pp. 233
    • Schena, F.P.1    Pascoe, M.D.2    Alberu, J.3
  • 21
    • 34548696864 scopus 로고    scopus 로고
    • MTOR inhibitors and their secondary effects in cardiac transplant recipients: A descriptive study
    • Moro J, Almenar L, Martínez-Dolz L, et al. mTOR inhibitors and their secondary effects in cardiac transplant recipients: A descriptive study. Transplant Proc 2007; 39: 2365.
    • (2007) Transplant Proc , vol.39 , pp. 2365
    • Moro, J.1    Almenar, L.2    Martínez-Dolz, L.3
  • 22
    • 33644696712 scopus 로고    scopus 로고
    • Three-year efficacy and safety results from a study of everolimus versus mycophenolate mofetil in de novo renal transplant patients
    • Vítko S, Margreiter R, Weimar W, et al. Three-year efficacy and safety results from a study of everolimus versus mycophenolate mofetil in de novo renal transplant patients. Am J Transplant 2005; 5: 2521.
    • (2005) Am J Transplant , vol.5 , pp. 2521
    • Vítko, S.1    Margreiter, R.2    Weimar, W.3
  • 23
    • 55749113683 scopus 로고    scopus 로고
    • Metabolic changes following conversion from an anticalcineurin-based therapy to an everolimus- based one: A single-center experience
    • Ayala M, Morales J, Fierro A, et al. Metabolic changes following conversion from an anticalcineurin-based therapy to an everolimus- based one: A single-center experience. Transplant Proc 2008; 40: 3265.
    • (2008) Transplant Proc , vol.40 , pp. 3265
    • Ayala, M.1    Morales, J.2    Fierro, A.3
  • 24
    • 34547453885 scopus 로고    scopus 로고
    • Comparison of sirolimus and everolimus in their effects on blood lipid profiles and haematological parameters in heart transplant recipients
    • Tenderich G, Fuchs U, Zittermann A, et al. Comparison of sirolimus and everolimus in their effects on blood lipid profiles and haematological parameters in heart transplant recipients. Clin Transplant 2007; 21: 536.
    • (2007) Clin Transplant , vol.21 , pp. 536
    • Tenderich, G.1    Fuchs, U.2    Zittermann, A.3
  • 25
    • 56049097497 scopus 로고    scopus 로고
    • Tolerance profile of the proliferation signal inhibitors everolimus and sirolimus in heart transplantation
    • Moro JA, Almenar L, Martínez-Dolz L, et al. Tolerance profile of the proliferation signal inhibitors everolimus and sirolimus in heart transplantation. Transplant Proc 2008; 40: 3034.
    • (2008) Transplant Proc , vol.40 , pp. 3034
    • Moro, J.A.1    Almenar, L.2    Martínez-Dolz, L.3
  • 26
    • 33846869205 scopus 로고    scopus 로고
    • Calcineurin inhibitor-free immunosuppression using everolimus in long term heart transplant recipients-Procedures of switching protocols and side effects
    • Rothenburger M, Stypmann J, Welp H, et al. Calcineurin inhibitor-free immunosuppression using everolimus in long term heart transplant recipients-Procedures of switching protocols and side effects. J Heart Lung Transplant 2006; 25: S166 (abstract 356).
    • (2006) J Heart Lung Transplant , vol.25
    • Rothenburger, M.1    Stypmann, J.2    Welp, H.3
  • 27
    • 34249279808 scopus 로고    scopus 로고
    • Prevention of acute rejection and allograft vasculopathy by everolimus in cardiac transplants recipients: A 24-month analysis
    • Viganò M, Tuzcu M, Benza R, et al. Prevention of acute rejection and allograft vasculopathy by everolimus in cardiac transplants recipients: A 24-month analysis. J Heart Lung Transplant 2007; 26: 584.
    • (2007) J Heart Lung Transplant , vol.26 , pp. 584
    • Viganò, M.1    Tuzcu, M.2    Benza, R.3
  • 28
    • 0034962528 scopus 로고    scopus 로고
    • High-throughput semiautomated 96-well liquid/liquid extraction and liquid chromatography/ mass spectrometric analysis of everolimus (RAD 001) and cyclosporin A (CsA) in whole blood
    • Brignol N, McMahon LM, Luo S, et al. High-throughput semiautomated 96-well liquid/liquid extraction and liquid chromatography/ mass spectrometric analysis of everolimus (RAD 001) and cyclosporin A (CsA) in whole blood. Rapid Commun Mass Spectrom 2001; 15: 898.
    • (2001) Rapid Commun Mass Spectrom , vol.15 , pp. 898
    • Brignol, N.1    McMahon, L.M.2    Luo, S.3


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