Regulatory B cells control dendritic cell functions

Immunotherapy

Volumn 3, Issue 4 SUPPL., 2011, Pages 19-20

  Lo Man, Richard ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

Author keywords

neonate; regulatory B cell; TLR

Indexed keywords

B CELL VACCINE; CANCER VACCINE; INTERLEUKIN 10; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CELL FUNCTION; CELL PROTECTION; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; DENDRITIC CELL; IMMUNOREGULATION; INNATE IMMUNITY; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; REGULATORY B CELL; REGULATORY MECHANISM; TUMOR IMMUNITY;

ANIMALS; ANIMALS, NEWBORN; B-LYMPHOCYTES; DENDRITIC CELLS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMANS; IMMUNE TOLERANCE; IMMUNITY, INNATE; IMMUNOMODULATION; INTERLEUKIN-10; MICE; NEOPLASMS;

EID: 79955593923     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/imt.11.34     Document Type: Article

References (16)

1. Jankovic D, Cheever AW, Kullberg MC et al.: CD4+ T cell-mediated granulomatous pathology in schistosomiasis is downregulated by a B cell-dependent mechanism requiring Fc receptor signaling. J. Exp. Med. 187(4), 619-629 (1998). (Pubitemid 28093364)
2. Velupillai P, Secor WE, Horauf AM, Harn DA: B-1 cell (CD5+B220+) outgrowth in murine schistosomiasis is genetically restricted and is largely due to activation by polylactosamine sugars. J. Immunol. 158(1), 338-344 (1997). (Pubitemid 127483874)
3. O'Garra A, Chang R, Go N, Hastings R, Haughton G, Howard M: Ly-1 B (B-1) cells are the main source of B cell-derived interleukin 10. Eur. J. Immunol. 22(3), 711-717 (1992).
4. Sun C, Deriaud E, Leclerc C, Lo-Man R: Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs. Immunity 22(4), 467-477 (2005). (Pubitemid 40545112)
5. Zhang X, Deriaud E, Jiao X, Braun D, Leclerc C, Lo-Man R: Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells. J. Exp. Med. 204(5), 1107-1118 (2007). (Pubitemid 46798154)
6. Neves P, Lampropoulou V, Calderon-Gomez E et al.: Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection. Immunity 33(5), 777-790 (2010).
7. Wolf SD, Dittel BN, Hardardottir F, Janeway CA Jr: Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J. Exp. Med. 184(6), 2271-2278 (1996). (Pubitemid 27023727)
8. Fillatreau S, Sweenie CH, Mcgeachy MJ, Gray D, Anderton SM: B cells regulate autoimmunity by provision of IL-10. Nat. Immunol. 3(10), 944-950 (2002). (Pubitemid 35154008)
9. Mizoguchi A, Mizoguchi E, Takedatsu H, Blumberg RS, Bhan AK: Chronic intestinal inflammatory condition generates IL-10- producing regulatory B cell subset characterized by CD1d upregulation. Immunity 16(2), 219-230 (2002). (Pubitemid 34211962)
10. Mauri C, Gray D, Mushtaq N, Londei M: Prevention of arthritis by interleukin 10-producing B cells. J. Exp. Med. 197(4), 489-501 (2003). (Pubitemid 36278604)
11. Blair PA, Noreña LY, Flores-Borja F et al.: CD19+CD24hiCD38hi B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients. Immunity 32(1), 129-140 (2010).
12. Inoue S, Leitner WW, Golding B, Scott D: Inhibitory effects of B cells on antitumor immunity. Cancer Res. 66(15), 7741-7747 (2006). (Pubitemid 44289234)
13. Shah S, Divekar AA, Hilchey SP et al.: Increased rejection of primary tumors in mice lacking B cells: inhibition of anti-tumor CTL and Th1 cytokine responses by B cells. Int. J. Cancer 117(4), 574-586 (2005). (Pubitemid 41504545)
14. Tadmor T, Zhang Y, Cho H-M, Podack ER, Rosenblatt JD: The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model. Cancer Immunol. Immunother. DOI: 10.1007/s00262-011-0972-z (2011) (Epub ahead of print).
15. Murai M, Turovskaya O, Kim G et al.: Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat. Immunol. 10(11), 1178-1184 (2009).
16. Reichardt P, Dornbach B, Rong S et al.: Naive B cells generate regulatory T cells in the presence of a mature immunologic synapse. Blood 110(5), 1519-1529 (2007). (Pubitemid 47443968)