-
2
-
-
0037050009
-
Seven-transmembrane-spanning receptors and heart function
-
DOI 10.1038/415206a
-
Rockman HA, Koch WJ, Lefkowitz RJ (2002) Seven-transmembrane-spanning receptors and heart function. Nature 415:206-212. (Pubitemid 34059526)
-
(2002)
Nature
, vol.415
, Issue.6868
, pp. 206-212
-
-
Rockman, H.A.1
Koch, W.J.2
Lefkowitz, R.J.3
-
3
-
-
0346687568
-
Adrenergic receptor knockout mice: Distinct functions of 9 receptor subtypes
-
DOI 10.1016/j.pharmthera.2003.10.004
-
Philipp M, Hein L (2004) Adrenergic receptor knockout mice: Distinct functions of 9 receptor subtypes. Pharmacol Ther 101:65-74. (Pubitemid 38068526)
-
(2004)
Pharmacology and Therapeutics
, vol.101
, Issue.1
, pp. 65-74
-
-
Philipp, M.1
Hein, L.2
-
4
-
-
0032563291
-
G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization
-
Lefkowitz RJ (1998) G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization. J Biol Chem 273:18677-18680.
-
(1998)
J Biol Chem
, vol.273
, pp. 18677-18680
-
-
Lefkowitz, R.J.1
-
6
-
-
0030296744
-
G protein-coupled receptors: Heterologous regulation of homologous desensitization and its implications
-
DOI 10.1016/S0165-6147(96)10048-1, PII S0165614796100481
-
Chuang TT, Iacovelli L, Sallese M, De Blasi A (1996) G protein-coupled receptors: Heterologous regulation of homologous desensitization and its implications. Trends Pharmacol Sci 17:416-421. (Pubitemid 26401700)
-
(1996)
Trends in Pharmacological Sciences
, vol.17
, Issue.11
, pp. 416-421
-
-
Chuang, T.T.1
Iacovelli, L.2
Sallese, M.3
De Blasi, A.4
-
7
-
-
0033824138
-
International union of pharmacology. XXIII. The angiotensin II receptors
-
de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T (2000) International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 52:415-472.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 415-472
-
-
De Gasparo, M.1
Catt, K.J.2
Inagami, T.3
Wright, J.W.4
Unger, T.5
-
8
-
-
33745530252
-
Pathophysiological regulation of the AT1-receptor and implications for vascular disease
-
Wassman S, Nickenig G (2006) Pathophysiological regulation of the AT1-receptor and implications for vascular disease. J Hypertens 24:515-521.
-
(2006)
J Hypertens
, vol.24
, pp. 515-521
-
-
Wassman, S.1
Nickenig, G.2
-
9
-
-
0037059518
-
1 receptor mRNA by calreticulin
-
DOI 10.1161/hh0102.102503
-
Nickenig G, et al. (2002) Destabilization of AT(1) receptor mRNA by calreticulin. Circ Res 90:53-58. (Pubitemid 34074608)
-
(2002)
Circulation Research
, vol.90
, Issue.1
, pp. 53-58
-
-
Nickenig, G.1
Michaelsen, F.2
Muller, C.3
Berger, A.4
Vogel, T.5
Sachinidis, A.6
Vetter, H.7
Bohm, M.8
-
11
-
-
0035147435
-
Protein S-nitrosylation: A physiological signal for neuronal nitric oxide
-
DOI 10.1038/35055104
-
Jaffrey SR, Erdjument-Bromage H, Ferris CD, Tempst P, Snyder SH (2001) Protein Snitrosylation: A physiological signal for neuronal nitric oxide. Nat Cell Biol 3:193-197. (Pubitemid 32118373)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.2
, pp. 193-197
-
-
Jaffrey, S.R.1
Erdjument-Bromage, H.2
Ferris, C.D.3
Tempst, P.4
Snyder, S.H.5
-
12
-
-
34247470682
-
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
-
DOI 10.1016/j.cell.2007.02.046, PII S009286740700387X
-
Whalen EJ, et al. (2007) Regulation of β-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2. Cell 129:511-522. (Pubitemid 46660966)
-
(2007)
Cell
, vol.129
, Issue.3
, pp. 511-522
-
-
Whalen, E.J.1
Foster, M.W.2
Matsumoto, A.3
Ozawa, K.4
Violin, J.D.5
Que, L.G.6
Nelson, C.D.7
Benhar, M.8
Keys, J.R.9
Rockman, H.A.10
Koch, W.J.11
Daaka, Y.12
Lefkowitz, R.J.13
Stamler, J.S.14
-
13
-
-
48349131772
-
S-nitrosylation of β-arrestin regulates β-adrenergic receptor traf.cking
-
Ozawa K, et al. (2008) S-nitrosylation of β-arrestin regulates β-adrenergic receptor traf.cking. Mol Cell 31:395-405.
-
(2008)
Mol Cell
, vol.31
, pp. 395-405
-
-
Ozawa, K.1
-
14
-
-
3242832595
-
Redox regulation of cell signalling
-
Lander HM, et al. (1996) Redox regulation of cell signalling. Nature 381:380-381. (Pubitemid 126515840)
-
(1996)
Nature
, vol.381
, Issue.6581
, pp. 380-381
-
-
Lander, H.M.1
Mllbank, A.J.2
Tauras, J.M.3
Hajjar, D.P.4
Hempstead, B.L.5
Schwartz, G.D.6
Kraemer, R.T.7
Mirza, U.A.8
Chait, B.T.9
Burk, S.C.10
Quilliam, L.A.11
-
15
-
-
0037085709
-
oby reactive oxygen species
-
DOI 10.1074/jbc.M107392200
-
Nishida M, et al. (2002) Activation mechanism of Gi and Go by reactive oxygen species. J Biol Chem 277:9036-9042. (Pubitemid 34952977)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.11
, pp. 9036-9042
-
-
Nishida, M.1
Schey, K.L.2
Takagahara, S.3
Kontani, K.4
Katada, T.5
Urano, Y.6
Nagano, T.7
Nagao, T.8
Kurose, H.9
-
16
-
-
0031611615
-
Downregulation of angiotensin II type 1 receptor gene transcription by nitric oxide
-
Ichiki T, et al. (1998) Downregulation of angiotensin II type 1 receptor gene transcription by nitric oxide. Hypertension 31:342-348.
-
(1998)
Hypertension
, vol.31
, pp. 342-348
-
-
Ichiki, T.1
-
17
-
-
67249152096
-
Cardiac fibroblasts: At the heart of myocardial remodeling
-
Porter KE, Turner NA (2009) Cardiac fibroblasts: At the heart of myocardial remodeling. Pharmacol Ther 123:255-278.
-
(2009)
Pharmacol Ther
, vol.123
, pp. 255-278
-
-
Porter, K.E.1
Turner, N.A.2
-
18
-
-
33751104984
-
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy
-
DOI 10.1038/sj.emboj.7601417, PII 7601417
-
Onohara N, et al. (2006) TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy. EMBO J 25:5305-5316. (Pubitemid 44764140)
-
(2006)
EMBO Journal
, vol.25
, Issue.22
, pp. 5305-5316
-
-
Onohara, N.1
Nishida, M.2
Inoue, R.3
Kobayashi, H.4
Sumimoto, H.5
Sato, Y.6
Mori, Y.7
Nagao, T.8
Kurose, H.9
-
19
-
-
20744441519
-
12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts
-
DOI 10.1074/jbc.M409397200
-
Fujii T, et al. (2005) Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. J Biol Chem 280:23041-23047. (Pubitemid 40853214)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.24
, pp. 23041-23047
-
-
Fujii, T.1
Onohara, N.2
Maruyama, Y.3
Tanabe, S.4
Kobayashi, H.5
Fukutomi, M.6
Nagamatsu, Y.7
Nishihara, N.8
Inoue, R.9
Sumimoto, H.10
Shibasaki, F.11
Nagao, T.12
Nishida, M.13
Kurose, H.14
-
20
-
-
0032540267
-
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
-
DOI 10.1016/S0092-8674(00)81573-1
-
Molkentin JD, et al. (1998) A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93:215-228. (Pubitemid 28180855)
-
(1998)
Cell
, vol.93
, Issue.2
, pp. 215-228
-
-
Molkentin, J.D.1
Lu, J.-R.2
Antos, C.L.3
Markham, B.4
Richardson, J.5
Robbins, J.6
Grant, S.R.7
Olson, E.N.8
-
21
-
-
38549129745
-
P2 receptors in cardiovascular regulation and disease
-
Erlinge D, Burnstock G (2008) P2 receptors in cardiovascular regulation and disease. Purinergic Signal 4:1-20.
-
(2008)
Purinergic Signal
, vol.4
, pp. 1-20
-
-
Erlinge, D.1
Burnstock, G.2
-
22
-
-
34247637676
-
6 receptors is a mediator of microglial phagocytosis
-
6 receptors is a mediator of microglial phagocytosis. Nature 446:1091-1095.
-
(2007)
Nature
, vol.446
, pp. 1091-1095
-
-
Koizumi, S.1
-
23
-
-
0037137123
-
2 nucleotide receptors mediate uridine 5′-triphosphate-induced intimal hyperplasia in collared rabbit carotid arteries
-
DOI 10.1161/01.CIR.0000038111.00518.35
-
Seye CI, et al. (2002) Functional P2Y2 nucleotide receptors mediate uridine 5′- triphosphate-induced intimal hyperplasia in collared rabbit carotid arteries. Circulation 106:2720-2726. (Pubitemid 35364928)
-
(2002)
Circulation
, vol.106
, Issue.21
, pp. 2720-2726
-
-
Seye, C.I.1
Kong, Q.2
Erb, L.3
Garrad, R.C.4
Krugh, B.5
Wang, M.6
Turner, J.T.7
Sturek, M.8
Gonzalez, F.A.9
Weisman, G.A.10
-
24
-
-
57149085654
-
P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis
-
Nishida M, et al. (2008) P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis. EMBO J 27:3104-3115.
-
(2008)
EMBO J
, vol.27
, pp. 3104-3115
-
-
Nishida, M.1
-
25
-
-
0032541056
-
Cain, a novel physiologic protein inhibitor of calcineurin
-
DOI 10.1074/jbc.273.29.18325
-
Lai MM, Burnett PE, Wolosker H, Blackshaw S, Snyder SH (1998) Cain, a novel physiologic protein inhibitor of calcineurin. J Biol Chem 273:18325-18331. (Pubitemid 28334757)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.29
, pp. 18325-18331
-
-
Lai, M.M.1
Burnett, P.E.2
Wolosker, H.3
Blackshaw, S.4
Snyder, S.H.5
-
26
-
-
34249673350
-
NFAT signaling and the invention of vertebrates
-
DOI 10.1016/j.tcb.2007.04.006, PII S0962892407001031
-
Wu H, Peisley A, Graef IA, Crabtree GR (2007) NFAT signaling and the invention of vertebrates. Trends Cell Biol 17:251-260. (Pubitemid 46829850)
-
(2007)
Trends in Cell Biology
, vol.17
, Issue.6
, pp. 251-260
-
-
Wu, H.1
Peisley, A.2
Graef, I.A.3
Crabtree, G.R.4
-
27
-
-
2342576807
-
GPCR expression in the heart; "new" receptors in myocytes and fibroblasts
-
Tang CM, Insel PA (2004) GPCR expression in the heart; "new" receptors in myocytes and fibroblasts. Trends Cardiovasc Med 14:94-99.
-
(2004)
Trends Cardiovasc Med
, vol.14
, pp. 94-99
-
-
Tang, C.M.1
Insel, P.A.2
-
28
-
-
0037155184
-
Transcription factor NF-κB is necessary for up-regulation of type 1 angiotensin II receptor mRNA in rat cardiac fibroblasts treated with tumor necrosis factor-α or interleukin-1β
-
DOI 10.1074/jbc.M107515200
-
Cowling RT, Gurantz D, Peng J, Dillmann WH, Greenberg BH (2002) Transcription factor NF-κ B is necessary for up-regulation of type 1 angiotensin II receptor mRNA in rat cardiac fibroblasts treated with tumor necrosis factor-α or interleukin-1 β. J Biol Chem 277:5719-5724. (Pubitemid 34968348)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.8
, pp. 5719-5724
-
-
Cowling, R.T.1
Gurantz, D.2
Peng, J.3
Dillmann, W.H.4
Greenberg, B.H.5
-
29
-
-
77952018609
-
Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation
-
Nishida M, et al. (2010) Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation. J Biol Chem 285:15268-15277.
-
(2010)
J Biol Chem
, vol.285
, pp. 15268-15277
-
-
Nishida, M.1
-
30
-
-
0032510832
-
Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene
-
DOI 10.1074/jbc.273.24.15148
-
Taylor BS, et al. (1998) Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene. J Biol Chem 273:15148-15156. (Pubitemid 28272813)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.24
, pp. 15148-15156
-
-
Taylor, B.S.1
De Vera, M.E.2
Ganster, R.W.3
Wang, Q.4
Shapiro, R.A.5
Morris Jr., S.M.6
Billiar, T.R.7
Geller, D.A.8
-
31
-
-
33751577221
-
Calcineurin regulates NFAT-dependent iNOS expression and protection of cardiomyocytes: Co-operation with Src tyrosine kinase
-
DOI 10.1016/j.cardiores.2006.05.026, PII S0008636306002513
-
Obasanjo-Blackshire K, et al. (2006) Calcineurin regulates NFAT-dependent iNOS expression and protection of cardiomyocytes: Co-operation with Src tyrosine kinase. Cardiovasc Res 71:672-683. (Pubitemid 44848292)
-
(2006)
Cardiovascular Research
, vol.71
, Issue.4
, pp. 672-683
-
-
Obasanjo-Blackshire, K.1
Mesquita, R.2
Jabr, R.I.3
Molkentin, J.D.4
Hart, S.L.5
Marber, M.S.6
Xia, Y.7
Heads, R.J.8
-
32
-
-
54949147176
-
New regulators of NF-kappaB in in.ammation
-
Ghosh S, Hayden MS (2008) New regulators of NF-kappaB in in.ammation. Nat Rev Immunol 8:837-848.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 837-848
-
-
Ghosh, S.1
Hayden, M.S.2
-
33
-
-
35649021739
-
NOS2 regulation of NF-kappaB by S-nitrosylation of p65
-
DOI 10.1074/jbc.M705929200
-
Kelleher ZT, Matsumoto A, Stamler JS, Marshall HE (2007) NOS2 regulation of NFkappaB by S-nitrosylation of p65. J Biol Chem 282:30667-30672. (Pubitemid 350035227)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.42
, pp. 30667-30672
-
-
Kelleher, Z.T.1
Matsumoto, A.2
Stamler, J.S.3
Marshall, H.E.4
-
34
-
-
0035852845
-
Inhibition of NF-κ B by S-nitrosylation
-
Marshall HE, Stamler JS (2001) Inhibition of NF-κ B by S-nitrosylation. Biochemistry 40: 1688-1693.
-
(2001)
Biochemistry
, vol.40
, pp. 1688-1693
-
-
Marshall, H.E.1
Stamler, J.S.2
-
35
-
-
9644262497
-
Phosphorylation of serine 468 by GSK-30 negatively regulates basal p65 NF-kappaB activity
-
DOI 10.1074/jbc.C400442200
-
Buss H, et al. (2004) Phosphorylation of serine 468 by GSK-3β negatively regulates basal p65 NF-kappaB activity. J Biol Chem 279:49571-49574. (Pubitemid 39577758)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.48
, pp. 49571-49574
-
-
Buss, H.1
Dorrie, A.2
Schmitz, M.L.3
Frank, R.4
Livingstone, M.5
Rescht, K.6
Kracht, M.7
-
36
-
-
0028349156
-
Nitric oxide synthases in mammals
-
Knowles RG, Moncada S (1994) Nitric oxide synthases in mammals. Biochem J 298:249-258. (Pubitemid 24072462)
-
(1994)
Biochemical Journal
, vol.298
, Issue.2
, pp. 249-258
-
-
Knowles, R.G.1
Moncada, S.2
-
37
-
-
2342510314
-
Identification of β-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways
-
DOI 10.1016/S1097-2765(04)00216-3, PII S1097276504002163
-
Gao H, et al. (2004) Identification of β-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways. Mol Cell 14:303-317. (Pubitemid 38591402)
-
(2004)
Molecular Cell
, vol.14
, Issue.3
, pp. 303-317
-
-
Gao, H.1
Sun, Y.2
Wu, Y.3
Luan, B.4
Wang, Y.5
Qu, B.6
Pei, G.7
-
38
-
-
2942554958
-
β-arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha
-
DOI 10.1073/pnas.0402851101
-
Witherow DS, Garrison TR, Miller WE, Lefkowitz RJ (2004) β-Arrestin inhibits NFkappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha. Proc Natl Acad Sci USA 101:8603-8607. (Pubitemid 38745817)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.23
, pp. 8603-8607
-
-
Witherow, D.S.1
Garrison, T.R.2
Miller, W.E.3
Lefkowitz, R.J.4
-
39
-
-
77954431122
-
β-arrestin 2 is required for B1 receptor-dependent post-translational activation of inducible nitric oxide synthase
-
Kuhr FK, Zhang Y, Brovkovych V, Skidgel RA (2010) β-arrestin 2 is required for B1 receptor-dependent post-translational activation of inducible nitric oxide synthase. FASEB J 24:2475-2483.
-
(2010)
FASEB J
, vol.24
, pp. 2475-2483
-
-
Kuhr, F.K.1
Zhang, Y.2
Brovkovych, V.3
Skidgel, R.A.4
-
40
-
-
34247868824
-
Angiotensin II type 1 receptor gene regulation: Transcriptional and posttranscriptional mechanisms
-
DOI 10.1161/HYPERTENSIONAHA.106.070565
-
Elton TS, Martin MM (2007) Angiotensin II type 1 receptor gene regulation: Transcriptional and posttranscriptional mechanisms. Hypertension 49:953-961. (Pubitemid 351664299)
-
(2007)
Hypertension
, vol.49
, Issue.5
, pp. 953-961
-
-
Elton, T.S.1
Martin, M.M.2
-
41
-
-
34547655975
-
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells
-
DOI 10.1038/nm1617, PII NM1617
-
Idzko M, et al. (2007) Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nat Med 13:913-919. (Pubitemid 47222044)
-
(2007)
Nature Medicine
, vol.13
, Issue.8
, pp. 913-919
-
-
Idzko, M.1
Hammad, H.2
Van Nimwegen, M.3
Kool, M.4
Willart, M.A.M.5
Muskens, F.6
Hoogsteden, H.C.7
Luttmann, W.8
Ferrari, D.9
Di Jr., V.F.10
Virchow, J.C.11
Lambrecht, B.N.12
-
42
-
-
77955272897
-
Uridine triphosphate (UTP) induces profibrotic responses in cardiac fibroblasts by activation of P2Y2 receptors
-
Braun OO, Lu D, Aroonsakool N, Insel PA (2010) Uridine triphosphate (UTP) induces profibrotic responses in cardiac fibroblasts by activation of P2Y2 receptors. J Mol Cell Cardiol 49:362-369.
-
(2010)
J Mol Cell Cardiol
, vol.49
, pp. 362-369
-
-
Braun, O.O.1
Lu, D.2
Aroonsakool, N.3
Insel, P.A.4
|