In vitro and in vivo testing of a novel regulatory system for gene therapy for intervertebral disc degeneration

Spine

Volumn 36, Issue 10, 2011, Pages

  Sowa, Gwendolyn ^a   Westrick, Edward ^a   Pacek, Corey ^a   Coelho, Paulo ^a   Patel, Devin ^a   Vadala, Gianluca ^b   Georgescu, Helga ^a   Vo, Nam ^a   Studer, Rebecca ^a,c   Kang, James ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ROME   (Italy)

^c VAPHS 151 W University Dr C   (United States)

Author keywords

adeno associated virus; gene therapy; Intervertebral disc; safety

Indexed keywords

GREEN FLUORESCENT PROTEIN; LIGAND; PARVOVIRUS VECTOR; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE; BRAIN; DURA MATER; EXPERIMENTAL RABBIT; FEMALE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; IN VITRO GENE TRANSFER; IN VIVO GENE TRANSFER; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; LIVER; NONHUMAN; NUCLEUS PULPOSUS; PARVOVIRUS INFECTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SPINAL CORD;

ADENOVIRIDAE; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; LIGANDS; RABBITS; TRANSFECTION; UP-REGULATION;

EID: 79955570301     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3181ed11c1     Document Type: Article

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