Automated speciation of mercury in the hair of breastfed infants exposed to ethylmercury from thimerosal-containing vaccines

Biological Trace Element Research

Volumn 140, Issue 3, 2011, Pages 262-271

  Dórea, José G ^a   Wimer, Wade ^b   Marques, Rejane C ^c   Shade, Christopher ^b  

^a UNIVERSITY OF BRASILIA   (Brazil)

^b Quicksilver Scientific LLC   (United States)

^c UNIVERSIDADE FEDERAL DE RONDÔNIA   (Brazil)

Author keywords

Ethylmercury; Hair; Methylmercury; Speciation; Thimerosal; Vaccines

Indexed keywords

MERCURY; METHYLMERCURY; THIOMERSAL;

ANALYTIC METHOD; ARTICLE; AUTOMATION; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); FEMALE; HAIR LEVEL; HUMAN; HUMAN TISSUE; INFANT; LIMIT OF DETECTION; MALE; QUANTITATIVE ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; SPECTROFLUOROMETRY;

CHILD, PRESCHOOL; ETHYLMERCURY COMPOUNDS; HAIR; HUMANS; MERCURY; METHYLMERCURY COMPOUNDS; THIMEROSAL; THIOUREA; VACCINES;

EID: 79955569316     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12011-010-8695-0     Document Type: Article

References (16)

1. ME Pichichero A Gentile N Giglio J Treanor, et al. 2008 Mercury levels in newborns and infants after receipt of thimerosal-containing vaccines Pediatrics 121 e208 e214 18245396 10.1542/peds.2006-3363 (Pubitemid 351198424)
2. GA Westphal A Schnuch TG Schultz, et al. 2000 Homozygous gene deletions of the glutathione S-transferase M1 and T1 are associated with thimerosal sensitization Int Arch Occup Environ Health 73 384 388 11007341 10.1007/s004200000159 1:CAS:528:DC%2BD3cXlsVKqt74%3D
3. AC Barbosa AA Boischio GA East, et al. 1995 Mercury contamination in the Brazilian Amazon. Environmental and occupational aspects Water Air Soil Pollut 80 109 121 10.1007/BF01189660 1:CAS:528:DyaK2MXnsVChsL8%3D (Pubitemid 26438462)
4. H Ohno R Doi Y Kashima 2004 Wide use of merthiolate may cause mercury poisoning in Mexico Bull Env Contam Toxicol 73 777 780 10.1007/s00128-004-0494-x 1:CAS:528:DC%2BD2cXpsFahsrY%3D (Pubitemid 40022351)
5. D Gibicar M Logar N Horvat, et al. 2007 Simultaneous determination of trace levels of ethylmercury and methylmercury in biological samples and vaccines using sodium tetra(n-propyl)borate as derivatizing agent Anal Bioanal Chem 388 329 340 17340078 10.1007/s00216-007-1208-0 1:CAS:528: DC%2BD2sXks1Crtbg%3D (Pubitemid 46675972)
6. RC Marques JG Dórea MF Fonseca, et al. 2007 Hair mercury in breast-fed infants exposed to thimerosal-preserved vaccines Eur J Ped 166 935 941 10.1007/s00431-006-0362-2 1:CAS:528:DC%2BD2sXotVOmt7k%3D (Pubitemid 47101349)
7. J Qvarnstrom L Lambertsson S Havarinasab, et al. 2003 Determination of methylmercury, ethylmercury and inorganic mercury in mouse tissues, following administration of thimerosal, by species-specific isotope dilution GC-inductively coupled plasma-MS Anal Chem 75 4120 4124 14632125 10.1021/ac0342370 (Pubitemid 37012543)
8. J Holmes D Lean 2006 Factors that influence methylmercury flux rates from wetland sediments Sci Total Environ 368 306 319 16410019 10.1016/j.scitotenv. 2005.11.027 1:CAS:528:DC%2BD28XotFeqtrk%3D (Pubitemid 44164506)
9. TM Burbacher DD Shen N Liberato, et al. 2005 Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal Environ Health Perspect 113 1015 1021 16079072 10.1289/ehp.7712 1:CAS:528:DC%2BD2MXpslSkuro%3D (Pubitemid 41149631)
10. G Zareba E Cernichiari R Hojo, et al. 2007 Thimerosal distribution and metabolism in neonatal mice: comparison with methyl mercury J Appl Toxicol 27 511 518 17582588 10.1002/jat.1272 1:CAS:528:DC%2BD2sXpsVGku7Y%3D (Pubitemid 47255505)
11. CW Shade RJ Hudson 2005 Determination of MeHg in environmental sample matrices using Hg-thiourea complex ion chromatography with on-line cold vapor generation and atomic fluorescence spectrometric detection Environ Sci Technol 39 4974 4982 16053099 10.1021/es0483645 1:CAS:528:DC%2BD2MXks1Sgurc%3D (Pubitemid 40966724)
12. BV Vermillion RJM Hudson 2007 Thiourea catalysis of MeHg ligand exchange between natural dissolved organic matter and a thiol-functionalized resin: a novel method of matrix removal and MeHg preconcentration for ultratrace Hg speciation analysis in freshwaters Anal Bioanal Chem 388 341 352 17342536 10.1007/s00216-007-1207-1 1:CAS:528:DC%2BD2sXks1Crur4%3D (Pubitemid 46675973)
13. CW Shade 2008 Automated simultaneous analysis of monomethyl and mercuric Hg in biotic samples by Hg-thiourea complex liquid chromatography following acidic thiourea leaching Environ Sci Technol 42 6604 6610 18800537 10.1021/es800187y 1:CAS:528:DC%2BD1cXovVOht7k%3D
14. L Magos 2003 Neurotoxic character of thimerosal and the allometric extrapolation of adult clearance half-time to infants J Appl Toxicol 23 263 269 12884410 10.1002/jat.918 1:CAS:528:DC%2BD3sXmtF2qtb4%3D (Pubitemid 36950296)
15. A Schnuch W Uter J Geier, et al. 1998 Contact allergies in healthcare workers. Results from the IVDKA Acta Derm Venerol 78 358 363 9779255 10.1080/000155598443060 1:STN:280:DyaK1cvlt1aktQ%3D%3D (Pubitemid 28396688)
16. JG Dórea 2007 Exposure to mercury during the first six months via human milk and vaccines: modifying risk factors Am J Perinat 24 387 400 10.1055/s-2007-982074 (Pubitemid 47254975)