Deceased donor neutrophil gelatinase-associated lipocalin and delayed graft function after kidney transplantation: A prospective study

Critical Care

Volumn 15, Issue 3, 2011, Pages

  Hollmen, Maria E ^a   Kyllönen, Lauri E ^a   Inkinen, Kaija A ^a   Lalla, Martti L T ^a   Merenmies, Jussi ^b   Salmela, Kaija T ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b FINNISH RED CROSS BLOOD SERVICE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; ACUTE PHASE PROTEIN; BIOLOGICAL MARKER; LCN2 PROTEIN, HUMAN; LIPOCALIN; ONCOPROTEIN;

ADOLESCENT; ADULT; ARTICLE; BLOOD ANALYSIS; CHILD; CREATININE BLOOD LEVEL; DELAYED GRAFT FUNCTION; DIET; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLOMERULUS FILTRATION RATE; GRAFT RECIPIENT; GRAFT SURVIVAL; HISTOPATHOLOGY; HUMAN; KIDNEY BIOPSY; KIDNEY DONOR; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SCHOOL CHILD; URINALYSIS; AGED; BLOOD; DONOR; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PREDICTIVE VALUE; URINE;

ACUTE-PHASE PROTEINS; ADULT; AGED; BIOLOGICAL MARKERS; DELAYED GRAFT FUNCTION; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY TRANSPLANTATION; LIPOCALINS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PROTO-ONCOGENE PROTEINS; TISSUE DONORS;

EID: 79955568236     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc10220     Document Type: Article

References (43)

1. Giral-Classe M, Hourmant M, Cantarovich D, Dantal J, Blancho G, Daguin P, Ancelet D, Soulillou JP. Delayed graft function of more than six days strongly decreases long-term survival of transplanted kidneys. Kidney Int 1998, 54:972-978. 10.1046/j.1523-1755.1998.00071.x, 9734625.
2. Domínguez J, Lira F, Rebolledo R, Troncoso P, Aravena C, Ortiz M, Gonzales R. Duration of delayed graft function is an important predictor of 1-year serum creatinine. Transplant Proc 2009, 41:131-132. 10.1016/j.transproceed.2008.10.028, 19249496.
3. Ferrer F, Mota A, Alves R, Bastos C, Macário F, Figueiredo A, Santos L, Roseiro A, Parada Pratas J, Nunes P, Campos M. Renal transplantation with expanded criteria donors: the experience of one Portuguese center. Transplant Proc 2009, 41:791-793. 10.1016/j.transproceed.2009.02.044, 19376353.
4. Johnston TD, Thacker LR, Jeon H, Lucas BA, Ranjan D. Sensitivity of expanded-criteria donor kidneys to cold ischaemia time. Clin Transplant 2004, 18(Suppl 12):28-32.
5. Ojo AO, Wolfe RA, Held PJ, Port FK, Schmouder RL. Delayed graft function: risk factors and implications for renal allograft survival. Transplantation 1997, 63:968-974. 10.1097/00007890-199704150-00011, 9112349.
6. Moreso F, Serón D, Gil-Vernet S, Riera L, Fulladosa X, Ramos R, Alsina J, Grinyó JM. Donor age and delayed graft function as predictors of renal allograft survival in rejection-free patients. Nephrol Dial Transplant 1999, 14:930-935. 10.1093/ndt/14.4.930, 10328472.
7. Port FK, Bragg-Gresham JL, Metzger RA, Dykstra DM, Gillespie BW, Young EW, Delmonico FL, Wynn JJ, Merion RM, Wolfe RA, Held PJ. Donor characteristics associated with reduced graft survival: an approach to expanding the pool of kidney donors. Transplantation 2002, 74:1281-1286. 10.1097/00007890-200211150-00014, 12451266.
8. Irish WD, McCollum DA, Tesi RJ, Owen AB, Brennan DC, Bailly JE, Schnitzler MA. Nomogram for predicting the likelihood of delayed graft function in adult cadaveric renal transplant recipients. J Am Soc Nephrol 2003, 14:2967-2674. 10.1097/01.ASN.0000093254.31868.85, 14569108.
9. Nyberg SL, Matas AJ, Kremers WK, Thostenson JD, Larson TS, Prieto M, Ishitani MB, Sterioff S, Stegall MD. Improved scoring system to assess adult donors for cadaver renal transplantation. Am J Transplant 2003, 3:715-721. 10.1034/j.1600-6143.2003.00111.x, 12780563.
10. Schold JD, Kaplan B, Baliga RS, Meier-Kriesche HU. The broad spectrum of quality in deceased donor kidneys. Am J Transplant 2005, 5:757-765. 10.1111/j.1600-6143.2005.00770.x, 15760399.
11. Mishra J, Dent C, Tarabishi R, Mitsnefes M, Ma Q, Kelly C, Ruff S, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P. Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury following cardiac surgery. Lancet 2005, 365:1231-1238. 10.1016/S0140-6736(05)74811-X, 15811456.
12. Wagener G, Jan M, Kim M, Mori K, Barasch JM, Sladen RN, Lee HT. Association between increases with urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery. Anesthesiology 2006, 105:485-491. 10.1097/00000542-200609000-00011, 16931980.
13. Haase-Fielitz A, Bellomo R, Devarajan P, Story D, Matalanis G, Dragun D, Haase M. Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery: a prospective cohort study. Crit Care Med 2009, 37:553-560. 10.1097/CCM.0b013e318195846e, 19114878.
14. Niemann CU, Walia A, Waldman J, Davio M, Roberts JP, Hirose R, Feiner J. Acute kidney injury during liver transplantation as determined by neutrophil gelatinase-associated lipocalin. Liver Transpl 2009, 15:1852-1860. 10.1002/lt.21938, 19938135, 19938135 .
15. Bachorzewska-Gajewska H, Malyszko J, Sitniewska E, Malyszko JS, Dobrzycki A. Neutrophil gelatinase-associated lipocalin (NGAL) correlations with cystatin C, serum creatinine, and eGFR in patients with normal serum creatinine undergoing coronary angiography. Nephrol Dial Transplant 2007, 22:295-296.
16. Haase M, Bellomo R, Devarajan P, Schlattmann P, Haase-Fielitz A, . NGAL Meta-Analysis Investigator Group Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis 2009, 54:1012-1024. 10.1053/j.ajkd.2009.07.020, 19850388, NGAL Meta-Analysis Investigator Group.
17. Siew ED, Ware LB, Gebretsadik T, Shintani A, Moons KG, Wickersham N, Bossert F, Ikizler TA. Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults. J Am Soc Nephrol 2009, 20:1823-1832. 10.1681/ASN.2008070673, 2723988, 19628673.
18. Cruz DN, de Cal M, Garzotto F, Perazella MA, Lentini P, Corradi V, Piccinni P, Ronco C. Plasma neutrophil gelatinase-associated lipocalin is an early biomarker for acute kidney injury in adult ICU population. Intensive Care Med 2010, 36:444-451. 10.1007/s00134-009-1711-1, 2820221, 19956925.
19. Bagshaw SM, Bennett M, Haase M, Haase-Fielitz A, Egi M, Morimatsu H, D'amico G, Goldsmith D, Devarajan P, Bellomo R. Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus non-septic acute kidney injury in critical illness. Intensive Care Med 2010, 36:452-461. 10.1007/s00134-009-1724-9, 19956924.
20. Kümpers P, Hafer C, Lukasz A, Lichtinghagen R, Brand K, Fliser D, Faulhaber-Walter R, Kielstein JT. Serum neutrophil gelatinase-associated lipocalin at inception of renal replacement therapy predicts survival in critically ill patients with acute kidney injury. Crit Care 2010, 14:R9. 10.1186/cc8861, 2875521, 20122150.
21. Nickolas TL, O'Rourke MJ, Yang J, Sise ME, Canetta PA, Barasch N, Buchen C, Khan F, Mori K, Giglio J, Devarajan P, Barasch J. Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury. Ann Intern Med 2008, 148:810-819. 2909852, 18519927.
22. Makris K, Markou N, Evodia E, Dimopoulou E, Drakopoulos I, Ntetsika K, Rizos D, Baltopoulos G, Haliassos A. Urinary neutrophil gelatinase-associated lipocalin as an early marker of acute kidney injury in critically ill multiple trauma patients. Clin Chem Lab Med 2009, 47:79-82. 10.1515/CCLM.2009.004, 19055468.
23. Parikh CR, Jani A, Mishra J, Ma Q, Kelly C, Barasch J, Edelstein CL, Devarajan P. Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation. Am J Transplant 2006, 6:1639-1645. 10.1111/j.1600-6143.2006.01352.x, 16827865.
24. Hall IE, Yarlagadda SG, Coca SG, Wang Z, Doshi M, Devarajan P, Han WK, Marcus RJ, Parikh CR. IL-18 and urinary NGAL predict dialysis and raft recovery after kidney transplantation. J Am Soc Nephrol 2010, 21:189-197. 10.1681/ASN.2009030264, 2799276, 19762491.
25. Kusaka M, Kuroyanagi Y, Mori T, Nagaoka K, Sasaki H, Maruyama T, Hayakawa K, Shiroki R, Kurahashi H, Hoshinaga K. Serum neutrophil gelatinase-associated lipocalin as a predictor of organ recovery from delayed graft function after kidney transplantation from donors after cardiac death. Cell Transplant 2008, 17:129-134. 10.3727/000000008783907116, 18472448.
26. Lebkowska U, Malyszko J, Lebkowska A, Koc-Zorawska A, Lebkowski W, Malyszko JS, Kowalewski R, Gacko M. Neutrophil gelatinase-associated lipocalin and cystatin C could predict renal outcome in patients undergoing kidney allograft transplantation: a prospective study. Transplant Proc 2009, 41:154-157. 10.1016/j.transproceed.2008.10.092, 19249501.
27. Hollmen M, Kyllönen L, Inkinen K, Lalla M, Salmela K. Urine neutrophil gelatinase-associated lipocalin: a marker for graft recovery after kidney transplantation. Kidney Int 2011, 79:89-98. 10.1038/ki.2010.351, 20861824.
28. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth T. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999, 130:461-470.
29. Schwartz GF, Haycock GB, Edelmann CM, Spitzer A. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 1976, 58:259-263.
30. Racusen LC, Solez K, Colvin RB, Bonsib SM, Castro MC, Cavallo T, Croker BP, Demetris AJ, Drachenberg CB, Fogo AB, Furness P, Gaber LW, Gibson IW, Glotz D, Goldberg JC, Grande J, Halloran PF, Hansen HE, Hartley B, Hayry PJ, Hill CM, Hoffman EO, Hunsicker LG, Lindblad AS, Marcussen N, Mihatsch MJ, Nadasdy T, Nickerson P, Olsen TS, Papadimitriou JC, et al. The Banff 97 working classification of renal allograft pathology. Kidney Int 1999, 55:713-723. 10.1046/j.1523-1755.1999.00299.x, 9987096.
31. Isoniemi HM, Krogerus L, von Willebrand E, Taskinen E, Ahonen J, Häyry P. Histopathological findings in well-functioning, long-term renal allografts. Kidney Int 1992, 41:155-160. 10.1038/ki.1992.21, 1593852.
32. Halloran PF, Aprile MA, Farewell V, Ludwin D, Smith EK, Tsai SY, Bear RA, Cole EH, Fenton SS, Cattran DC. Early function as the principal correlate of graft survival: a multivariate analysis of 200 cadaveric renal transplants treated with a protocol incorporating antilymphocyte globulin and cyclosporine. Transplantation 1988, 46:223-228. 10.1097/00007890-198808000-00007, 3043779.
33. Bennett M, Dent CL, Ma Q, Dastrala S, Grenier F, Workman R, Syed H, Ali S, Barasch J, Devarajan P. Urine NGAL predicts severity of acute kidney injury after cardiac surgery: a prospective study. Clin J Am Soc Nephrol 2008, 3:665-673. 10.2215/CJN.04010907, 2386703, 18337554.
34. Wheeler DS, Devarajan P, Ma Q, Harmon K, Monaco M, Cvijanovich N, Wong HR. Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock. Crit Care Med 2008, 36:1297-1303. 10.1097/CCM.0b013e318169245a, 2757115, 18379258.
35. Liu Q, Nielsen-Hamilton M. Identification of a new acute phase protein. J Biol Chem 1995, 270:22565-22570. 10.1074/jbc.270.38.22565, 7545679.
36. Cowland JN, Borregaard N. Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans. Genomics 1997, 45:17-23. 10.1006/geno.1997.4896, 9339356.
37. Mishra J, Ma Q, Prada A, Mitsnefes M, Zahedi K, Yang J, Barasch J, Devarajan P. Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J Am Soc Nephrol 2003, 14:2534-2543. 10.1097/01.ASN.0000088027.54400.C6, 14514731.
38. Meheus LA, Fransen LM, Raymackers JG, Blockx HA, Van Beeumen JJ, Van Bun SM, Van de Voorde A. Identification by microsequencing of lipopolysaccharide-induced proteins secreted by mouse macrophages. J Immunol 1993, 151:1535-1547.
39. Cowland JB, Sørensen OE, Sehested M, Borregaard N. Neutrophil gelatinase-associated lipocalin is up-regulated in human epithelial cells by IL-1β, but not by TNF-α. J Immunol 2003, 171:6630-6639.
40. Grenier FC, Ali S, Syed H, Workman R, Martens F, Liao M, Wang Y, Wong PY. Evaluation of the ARCHITECT urine NGAL assay: assay performance, specimen handling requirements and biological variability. Clin Biochem 2010, 43:625-620.
41. Mori K, Lee HT, Rapaport D, Drexler IR, Foster K, Yang J, Schmidt-Ott KM, Chen X, Li JY, Weiss S, Mishra J, Cheema FH, Markowitz G, Suganami T, Sawai K, Mukoyama M, Kunis C, D'Agati V, Devarajan P, Barasch J. Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J Clin Invest 2005, 115:610-621. 548316, 15711640.
42. Schmidt-Ott KM, Mori K, Kalandadze A, Li JY, Paragas N, Nicholas T, Devarajan P, Barasch J. Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia. Curr Opin Nephrol Hypertens 2006, 15:442-449. 10.1097/01.mnh.0000232886.81142.58, 16775460.
43. Schmidt-Ott KM, Mori K, Li JY, Kalandadze A, Cohen DJ, Devarajan P, Barasch J. Dual action of neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol 2007, 18:407-413. 10.1681/ASN.2006080882, 17229907.