Gene expression following exposure to celecoxib in humans: Pathways of inflammation and carcinogenesis are activated in tumors but not normal tissues

Digestion

Volumn 84, Issue 3, 2011, Pages 169-184

  Sagiv, Eyal ^a,b   Sheffer, Michal ^c   Kazanov, Diana ^a   Shapira, Shiran ^a,b   Naumov, Inna ^a,b   Kraus, Sarah ^a,b   Domany, Eytan ^c   Arber, Nadir ^a,b  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Carcinogenesis; Celecoxib; Cell cycle; Colorectal cancer; Gene expression analyses; Genomic profiling; Inflammation

Indexed keywords

CALCINEURIN; CELECOXIB; CYCLIN D1; DNA; LYMPHOTOXIN; NOTCH RECEPTOR; PLACEBO; PROTEIN LYSINE 6 OXIDASE; RAS PROTEIN; RNA;

ARTICLE; CANCER SCREENING; CARCINOGENESIS; CELL CYCLE REGULATION; COLONOSCOPY; COLORECTAL CANCER; COLORECTAL SURGERY; DISEASE ASSOCIATION; DNA MICROARRAY; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; INFLAMMATION; PRIORITY JOURNAL; RNA EXTRACTION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADENOCARCINOMA; CELL CYCLE; CELL TRANSFORMATION, NEOPLASTIC; COLONIC POLYPS; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 2 INHIBITORS; GENE EXPRESSION; HUMANS; INFLAMMATION; INTESTINAL MUCOSA; MICROARRAY ANALYSIS; PYRAZOLES; RANDOM ALLOCATION; RNA, NEOPLASM; SIGNAL TRANSDUCTION; SULFONAMIDES; TRANSFORMING GROWTH FACTOR BETA;

EID: 79955563958     PISSN: 00122823     EISSN: 14219867     Source Type: Journal    
DOI: 10.1159/000322688     Document Type: Article

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