WFDC1 expression identifies memory CD4 T- lymphocytes rendered vulnerable to cell-cell HIV-1 transfer by promoting intercellular adhesive junctions

Retrovirology

Volumn 8, Issue , 2011, Pages

  Alvarez, Raymond A ^a   Thorborn, Georgina ^a   Reading, James L ^a   Reddy, Shalini K ^a   Vyakarnam, Annapurna ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PROTEIN; GAG PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; PROTEIN WFDC1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; PROTEIN; WFDC1 PROTEIN, HUMAN;

ARTICLE; CD4+ T LYMPHOCYTE; CELL JUNCTION; CELL TRANSFER; COCULTURE; CONJUGATION; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VIVO STUDY; LYMPHOCYTE CLONE; MEMORY T LYMPHOCYTE; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN TRANSPORT; PROTEIN VARIANT; REVERSE TRANSCRIPTION; VIROLOGICAL SYNAPSE; VIRUS CELL INTERACTION; VIRUS PATHOGENESIS; VIRUS TRANSMISSION; CELL ADHESION; CELL FUSION; CHEMISTRY; GROWTH, DEVELOPMENT AND AGING; LEUKEMIA CELL LINE; PATHOGENICITY; PHYSIOLOGY; T LYMPHOCYTE SUBPOPULATION; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

CD4-POSITIVE T-LYMPHOCYTES; CELL ADHESION; CELL FUSION; HIV-1; HUMANS; JURKAT CELLS; PROTEINS; T-LYMPHOCYTE SUBSETS;

EID: 79955562240     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-8-29     Document Type: Article

References (46)

1. Sherer NM, Lehmann MJ, Jimenez-Soto LF, Horensavitz C, Pypaert M, Mothes W. Retroviruses can establish filopodial bridges for efficient cell-to-cell transmission. Nat Cell Biol 2007, 9:310-315. 10.1038/ncb1544, 2628976, 17293854.
2. Sowinski S, Jolly C, Berninghausen O, Purbhoo MA, Chauveau A, Köhler K, Oddos S, Eissmann P, Brodsky FM, Hopkins C, Onfelt B, Sattentau Q, Davis DM. Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission. Nat Cell Biol 2008, 10:211-219. 10.1038/ncb1682, 18193035.
3. Jolly C, Sattentau QJ. Retroviral spread by induction of virological synapses. Traffic 2004, 5:643-650. 10.1111/j.1600-0854.2004.00209.x, 15296489.
4. Sattentau Q. Avoiding the void: cell-to-cell spread of human viruses. Nat Rev Microbiol 2008, 6:815-826. 10.1038/nrmicro1972, 18923409.
5. Dimitrov DS, Willey RL, Sato H, Chang LJ, Blumenthal R, Martin MA. Quantitation of human immunodeficiency virus type 1infection kinetics. J Virol 1993, 67:2182-2190. 240333, 8445728.
6. Jolly C, Kashefi K, Hollinshead M, Sattentau QJ. HIV-1 cell-to-cell transfer across an Env-induced, actin-dependent synapse. J Exp Med 2004, 199:283-293. 10.1084/jem.20030648, 2211771, 14734528.
7. Carr JM, Hocking H, Li P, Burrell CJ. Rapid and efficient cell-to-cell transmission of human immunodeficiency virus infection from monocyte-derived macrophages to peripheral blood lymphocytes. Virology 1999, 265:319-329. 10.1006/viro.1999.0047, 10600603.
8. Chen P, Hubner W, Spinelli MA, Chen BK. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses. J Virol 2007, 81:12582-12595. 10.1128/JVI.00381-07, 2169007, 17728240.
9. Sato H, Orenstein J, Dimitrov D, Martin M. Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles. Virology 1992, 186:712-724. 10.1016/0042-6822(92)90038-Q, 1370739.
10. Sourisseau M, Sol-Foulon N, Porrot F, Blanchet F, Schwartz O. Inefficient human immunodeficiency virus replication in mobile lymphocytes. J Virol 2007, 81:1000-1012. 10.1128/JVI.01629-06, 1797449, 17079292.
11. Hübner W, McNerney GP, Chen P, Dale BM, Gordon RE, Chuang FY, Li XD, Asmuth DM, Huser T, Chen BK. Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science 2009, 323:1743-1747. 10.1126/science.1167525, 2756521, 19325119.
12. Rudnicka D, Feldmann J, Porrot F, Wietgrefe S, Guadagnini S, Prévost MC, Estaquier J, Haase AT, Sol-Foulon N, Schwartz O. Simultaneous HIV Cell-to-Cell Transmission To Multiple Targets Through Polysynapses. J Virol 2009, 83:6234-46. 10.1128/JVI.00282-09, 2687379, 19369333.
13. Nobile C, Petit C, Moris A, Skrabal K, Abastado JP, Mammano F, Schwartz O. Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes. J Virol 2005, 79:5386-5399. 10.1128/JVI.79.9.5386-5399.2005, 1082762, 15827153.
14. Vasiliver-Shamis G, Cho MW, Hioe CE, Dustin ML. Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signalling creates an F-actin-depleted zone in the virological synapse. J Virol 2009, 83:11341-11355. 10.1128/JVI.01440-09, 2772796, 19710135.
15. Sol-Foulon N, Sourisseau M, Porrot F, Thoulouze MI, Trouillet C, Nobile C, Blanchet F, di Bartolo V, Noraz N, Taylor N, Alcover A, Hivroz C, Schwartz O. ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation. EMBO J 2007, 26:516-526. 10.1038/sj.emboj.7601509, 1783460, 17215865.
16. Jolly C, Sattentau QJ. Human immunodeficiency virus type 1 assembly, budding, and cell-cell spread in T cells take place in tetraspanin-enriched plasma membrane domains. J Virol 2007, 81:7873-7884. 10.1128/JVI.01845-06, 1951303, 17522207.
17. Jolly C, Mitar I, Sattentau QJ. Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells. J Virol 2007, 81:13916-13921. 10.1128/JVI.01585-07, 2168851, 17913807.
18. Arthos J, Cicala C, Martinelli E, Macleod K, Van Ryk D, Wei D, Xiao Z, Veenstra TD, Conrad TP, Lempicki RA, McLaughlin S, Pascuccio M, Gopaul R, McNally J, Cruz CC, Censoplano N, Chung E, Reitano KN, Kottilil S, Goode DJ, Fauci A. SHIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells. Nat Immunol 2008, 9:301-309. 10.1038/ni1566, 18264102.
19. Krementsov DN, Weng J, Lambele M, Roy NH, Thali M. Tetraspanins regulate cell-to-cell transmission of HIV-1. Retrovirology 2009, 6:64. 10.1186/1742-4690-6-64, 2714829, 19602278.
20. Tsunetsugu-Yokota Y, Yasuda S, Sugimoto A, Yagi T, Azuma M, Yagita H, Akagawa K, Takemori T. Efficient virus transmission from dendritic cells to CD4+ T cells in response to antigen depends on close contact through adhesion molecules. Virology 1997, 239:259-268. 10.1006/viro.1997.8895, 9434717.
21. McDonald D, Wu L, Bohks SM, KewalRamani VN, Unutmaz D, Hope TJ. Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science 2003, 300:1295-1297. 10.1126/science.1084238, 12730499.
22. Jolly C, Sattentau QJ. Human immunodeficiency virus type 1 virological synapse formation in T cells requires lipid raft integrity. J Virol 2005, 79:12088-12094. 10.1128/JVI.79.18.12088-12094.2005, 1212596, 16140785.
23. Alvarez R, Reading J, King DF, Hayes M, Easterbrook P, Farzaneh F, Ressler S, Yang F, Rowley D, Vyakarnam A. WFDC1/ps20 is a novel innate immunomodulatory signature protein of human immunodeficiency virus (HIV)-permissive CD4+ CD45RO+ memory T cells that promotes infection by upregulating CD54 integrin expression and is elevated in HIV type 1 infection. J Virol 2008, 82:471-486. 10.1128/JVI.00939-07, 2224370, 17942534.
24. Tardif MR, Tremblay MJ. LFA-1 is a key determinant for preferential infection of memory CD4+ T cells by human immunodeficiency virus type 1. J Virol 2005, 79:13714-13724. 10.1128/JVI.79.21.13714-13724.2005, 1262559, 16227291.
25. Liao Z, Roos JW, Hildreth JE. Increased infectivity of HIV type 1 particles bound to cell surface and solid-phase ICAM-1 and VCAM-1 through acquired adhesion molecules LFA-1 and VLA-4. AIDS Res Hum Retroviruses 2000, 16:355-366. 10.1089/088922200309232, 10716373.
26. Fortin JF, Cantin R, Lamontagne G, Tremblay M. Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity. J Virol 1997, 71:3588-3596. 191506, 9094631.
27. Tardif MR, Tremblay MJ. Presence of host ICAM-1 in human immunodeficiency virus type 1 virions increases productive infection of CD4+ T lymphocytes by favoring cytosolic delivery of viral material. J Virol 2003, 77:12299-12309. 10.1128/JVI.77.22.12299-12309.2003, 254246, 14581566.
28. Bingle CD, Vyakarnam A. Novel innate immune functions of the whey acidic protein family. Trends Immunol 2008, 29:444-453. 10.1016/j.it.2008.07.001, 18676177.
29. Ranganathan S, Simpson KJ, Shaw DC, Nicholas KR. The whey acidic protein family: a new signature motif and three-dimensional structure by comparative modeling. J Mol Graph Model 1999, 17:106. 10.1016/S1093-3263(99)00023-6, 10680116.
30. Moreau T, Baranger K, Dadé S, Dallet-Choisy S, Guyot N, Zani ML. Multifaceted roles of human elafin and secretory leukocyte proteinase inhibitor (SLPI), two serine protease inhibitors of the chelonianin family. Biochimie 2008, 90:284-295. 10.1016/j.biochi.2007.09.007, 17964057.
31. McAlhany SJ, Ressler SJ, Larsen M, Tuxhorn JA, Yang F, Dang TD, Rowley DR. Promotion of angiogenesis by ps20 in the differential reactive stroma prostate cancer xenograft model. Cancer Res 2003, 63:5859-5865.
32. Berrier AL, Yamada KM. Cell-matrix adhesion. J Cell Physiol 2007, 213:565-573. 10.1002/jcp.21237, 17680633.
33. Hynes RO, Lively JC, McCarty JH, Taverna D, Francis SE, Hodivala-Dilke K, Xiao Q. The diverse roles of integrins and their ligands in angiogenesis. Cold Spring Harb Symp Quant Biol 2002, 67:143-153. 10.1101/sqb.2002.67.143, 12858535.
34. Larsen M, Ressler SJ, Lu B, Gerdes MJ, McBride L, Dang TD, Rowley DR. Molecular cloning and expression of ps20 growth inhibitor. A novel WAP-type "four-disulfide core" domain protein expressed in smooth muscle. J Biol Chem 1998, 273:4574-4584. 10.1074/jbc.273.8.4574, 9468514.
35. Ruggiero E, Bona R, Muratori C, Federico M. Virological consequences of early events following cell-cell contact between human immunodeficiency virus type 1-infected and uninfected CD4+ cells. J Virol 2008, 82:7773-7789. 10.1128/JVI.00695-08, 2519596, 18508887.
36. Blanco J, Bosch B, Fernández-Figueras MT, Barretina J, Clotet B, Esté JA. High level of coreceptor-independent HIV transfer induced by contacts between primary CD4 T cells. J Biol Chem 2004, 279:51305-51314. 10.1074/jbc.M408547200, 15371410.
37. Bosch B, Grigorov B, Senserrich J, Clotet B, Darlix JL, Muriaux D, Este JA. A clathrin-dynamin-dependent endocytic pathway for the uptake of HIV-1 by direct T cell-T cell transmission. Antiviral Res 2008, 80:185-193. 10.1016/j.antiviral.2008.06.004, 18602423.
38. Puigdomenech I, Massanella M, Cabrera C, Clotet B, Blanco J. On the steps of cell-to-cell HIV transmission between CD4 T cells. Retrovirology 2009, 6:89. 10.1186/1742-4690-6-89, 2768678, 19825175.
39. Bousso P, Robey EA. Dynamic behavior of T cells and thymocytes in lymphoid organs as revealed by two-photon microscopy. Immunity 2004, 21:349-355. 10.1016/j.immuni.2004.08.005, 15357946.
40. Celli S, Garcia Z, Bousso P. CD4 T cells integrate signals delivered during successive DC encounters in vivo. J Exp Med 2005, 202:1271-1278. 10.1084/jem.20051018, 2213240, 16275764.
41. Martin N, Welsch S, Jolly C, Briggs JA, Vaux D, Sattentau QJ. Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition. J Virol 2010, 84:3516-3527. 10.1128/JVI.02651-09, 2838118, 20089656.
42. Vasiliver-Shamis G, Cho MW, Hioe CE, Dustin ML. Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse. J Virol 2009, 83:11341-11355. 10.1128/JVI.01440-09, 2772796, 19710135.
43. Pais-Correia AM, Sachse M, Guadagnini S, Robbiati V, Lasserre R, Gessain A, Gout O, Alcover A, Thoulouze MI. Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses. Nat Med 2010, 16:83-89. 10.1038/nm.2065, 20023636.
44. Stewart PL, Nemerow GR. Cell integrins: commonly used receptors for diverse viral pathogens. Trends Microbiol 2007, 15:500-507. 10.1016/j.tim.2007.10.001, 17988871.
45. Vyakarnam A, Eyeson J, Teo I, Zuckerman M, Babaahmady K, Schuitemaker H, Shaunak S, Rostron T, Rowland-Jones S, Simmons G, Clapham P. Evidence for a post-entry barrier to R5 HIV-1 infection of CD4 memory T cells. AIDS 2001, 15:1613-1626. 10.1097/00002030-200109070-00003, 11546935.
46. Wu Y, Marsh JW. Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA. Science 2001, 293:1503-1506. 10.1126/science.1061548, 11520990.